Clinical trials: Chronic Neurogenic Cough
Post Nasal Drip
Capsaicin Cough Threshold in Chronic Cough Due to Postnasal Drip
This study is being done to find out why some people with mucus dripping down the back of their throat have a nagging cough while others do not cough.
- Trial name
- NCT00588627
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Upper-Airway Cough Syndrome
Laryngeal Cryotherapy for Refractory Neurogenic Cough
This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure
- Trial name
- NCT05665244
- Testing
- Laryngeal cryotherapy, Cryoprobe
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Texas Southwestern Medical Center
Refractory Chronic Cough
Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough
This research study is evaluating the effectiveness of escalating doses of Amitriptyline and Duloxetine in reducing cough frequency in patients with refractory chronic cough (RCC)
- Trial name
- MACS-1 (NCT05110144)
- Testing
- Duloxetine 30 MG, Duloxetine 60 MG, Amitriptyline 25 MG
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Chronic Cough (CC), Refractory Chronic Cough
Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough
This study is testing new ways to help people who have chronic cough that has not improved with typical treatments. One approach is called behavioral cough suppression (BCS) therapy, which teaches people techniques to stop…
- Conditions
- Chronic Cough (CC), Refractory Chronic Cough, Unexplained Chronic Cough
- Trial name
- CoughLESS (NCT06960759)
- Testing
- BCS+inactive, BCS+active
- Where
- 3 sites in United States
- Volunteers
- 135 people
- Sponsor
- University of Montana
Cough, Superior Laryngeal Nerve Block
Efficacy of SLN Block for Chronic Cough
This is a research study to find out if superior laryngeal nerve blocks are an effective way to reduce cough when compared to placebo (a substance without any medical value).
- Conditions
- Cough, Superior Laryngeal Nerve Block, Neurogenic Cough
- Trial name
- NCT04421092
- Testing
- Superior laryngeal nerve block, Injection of steroid-lidocaine mixture
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Laryngeal Nerve Block, Chronic Neurogenic Cough
Laryngeal Nerve Block for Chronic Cough
The purpose of this study is to study the potential benefit of treating chronic neurogenic cough by blocking the nerve responsible for the disease with an injection of local anesthetic/steroid mixture versus a placebo.
- Conditions
- Laryngeal Nerve Block, Chronic Neurogenic Cough, Laryngeal Hypersensitivity
- Trial name
- NCT05292677
- Testing
- Steroid/Anesthesia Mixture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eastern Virginia Medical School
Chronic Cough (CC), Laryngeal Disease
Efficacy of Intramuscular Steroid Injection for Chronic Cough.
The primary goal of this study is to test the hypothesis that injecting steroid intramuscularly is an effective treatment for unexplained chronic cough.
- Conditions
- Chronic Cough (CC), Laryngeal Disease, Coughing
- Trial name
- NCT06634823
- Testing
- Triamcinolone Acetonide Injectable Suspension, Saline injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Cough
Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough
The purpose of this study is to evaluate if office-based injection of a local anesthetic/steroid combination at the area of one superior laryngeal nerve can decrease cough frequency and alleviate symptoms of chronic cough in…
- Trial name
- NCT04642352
- Testing
- superior laryngeal nerve block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham