Clinical trials: Chronic Nociceptive Pain, active
Nociceptive Pain, Axial Back Pain
Ultra Low Frequency Neuromodulation for Nociceptive Chronic Low Back Pain
The goal of this clinical trial is to learn if Ultra Low Frequency (ULF) neuromodulation works to treat nociceptive chronic low back pain in adults. It will also evaluate the safety of ULF therapy.
- Trial name
- NCT06763653
- Testing
- ULF therapy, CMM
- Where
- 3 sites in Australia
- Volunteers
- 303 people
- Sponsor
- Presidio Medical, Inc
Nerve Pain, Neuropathic Pain
PETMRI for Chronic Pain from Spinal or Peripheral Nerve Origin
The purpose of this study is to compare the uptake of [18F]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain with Spinal or Peripheral Nerve Origin.
- Conditions
- Nerve Pain, Neuropathic Pain, Nociceptive Pain, MIxed Pain (Nociceptive and Neuropathic)
- Trial name
- NCT06599151
- Testing
- [18F]FTC-146
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gastroparesis, Chronic Abdominal Pain
Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis
Gastroparesis is a disorder characterized by delayed gastric emptying and symptoms including nausea, vomiting, and abdominal pain.
- Trial name
- HEAL (NCT07556237)
- Testing
- Enterra™ neurostimulator
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Louisville
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Pain, Mixed Pain (Nociceptive and Neuropathic)
S1R Imaging-Based Cryoneurolysis in Chronic Pain
The goal of this clinical trial is to determine whether a sigma-1 receptor PET/MRI scan can help identify the specific nerves responsible for chronic pain.
- Trial name
- NCT07768501
- Testing
- [18F]-FTC-146
- Volunteers
- 6 people
- Sponsor
- Davidzon, Guido, M.D.
Chronic Pain, Nociceptive Pain
Central Sensitisation in Nociceptive and Neuropathic Pain
This study aims to investigate differences in central sensitization among patients with chronic nociceptive pain, neuropathic pain, and mixed pain conditions.
- Conditions
- Chronic Pain, Nociceptive Pain, Neuropathic Pain, Mixed Pain (Nociceptive and Neuropathic)
- Trial name
- ALGOS (NCT07321080)
- Testing
- Neuropsychological assessment, Laser evoked potentials
- Where
- Italy
- Volunteers
- 185 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Chronic Pain, Persistent Pain
Pleasant Touch Perception in Persistent Pain.
The goal of this observational study is to learn how individuals with chronic pain experience pleasant touch and how often they are exposed to such touch in their daily lives.
- Trial name
- NCT07551687
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Chronic Pain, Somatic Pain
Pain Acceptance Training in Patients Experiencing Emotional Distress and Somatic Symptoms: Examination of Dialectical Thinking as a Mediating Factor
Somatic symptoms, including physical pain, are highly prevalent among mental health patients. Current treatments have limited effectiveness for these symptoms, primarily because of patients' diminished introspective capacity and…
- Conditions
- Chronic Pain, Somatic Pain, Comorbid Pain and Emotional Difficulties
- Trial name
- NCT07067619
- Testing
- Pain-acceptance intervention
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- University of Haifa
Knee Osteoarthritis
Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis
The purpose of this research study is to compare muscle activation, changes in pain sensitivity, and brain function, between different walking conditions, including walking to music, walking to metronome, and walking without…
- Trial name
- NCT07537114
- Testing
- Rhythmic Auditory Stimulation with music, Rhythmic Auditory Stimulation with metronome, Control
- Volunteers
- 20 people
- Sponsor
- Boston University Charles River Campus