Clinical trials: Chronic Obstr Lung Disease
Chronic Obstructive Pulmonary Disease
Effects of Indacaterol in Symptomatic COPD Patients With Low Risk of Exacerbations
This study compared the efficacy of indacaterol versus placebo in COPD patients classified as GOLD 2014 Patient Group B. This was a 2-arm parallel group study that recruited COPD patients classified by GOLD Patient Gorup B.
- Trial name
- NCT02418468
- Testing
- Indacaterol
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD)
Study Comparing Dual Combination of Product (Budesonide and Formoterol) Given Via Two Different Inhalers. To See Which One Results in the Best Effect on Breathing.
Study comparing the same drugs as a dual combination product (budesonide and formoterol) given via two different inhalers. To see which one results in the best effect on breathing.
- Trial name
- NCT04078126
- Testing
- BFF, Symbicort Turbuhaler
- Where
- 4 sites in Germany
- Volunteers
- 35 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Treatment of Chronic Obstructive Pulmonary Disease (COPD) With Diffusion Capacity Defect by REGEND001 Cell Therapy
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide with the characterization of obstructed airflow.
- Trial name
- NCT05638776
- Testing
- REGEND001 cell therapy
- Where
- 8 sites in China
- Volunteers
- 58 people
- Sponsor
- Regend Therapeutics
Chronic Obstructive Pulmonary Disease
Nitrate Supplementation in Chronic Obstructive Pulmonary Disease (COPD)
Each subject will consume (in a randomized fashion) both the intervention beverage (nitrate solution) and the placebo, separated by a 1 wk washout period.
- Trial name
- NCT02084758
- Testing
- Nitrate supplementation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Chronic Obstructive Pulmonary Disease
Involvement of Nervous System in Muscle Weakness in COPD Patients
The purpose of this study is to determine whether nervous system alterations and motor drive failure can contribute to muscle weakness in COPD during voluntary movement.
- Trial name
- DesCoM-1 (NCT01679782)
- Where
- France
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Chronic Obstructive Pulmonary Disease
Comparison of the Effects of Indacaterol and Tiotropium on Inspiratory Capacity
This study compared the effects of a single dose of indacaterol with that of a single dose of tiotropium on inspiratory capacity.
- Trial name
- NCT00999908
- Testing
- Indacaterol 150 μg, Tiotropium 18 μg
- Where
- 11 sites in Italy
- Volunteers
- 54 people
- Sponsor
- Novartis Pharmaceuticals
Pulmonary Disease, Chronic Obstructive, Exercise
Change of Lung Function After Exercise in Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to evaluate the changes of lung function before and after the exercise in patients with chronic obstructive pulmonary disease.The assessment of quality of life is also carried out through…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Exercise, Lung Function Decreased, Quality of Life
- Trial name
- NCT03551197
- Testing
- Budesonide and formoterol bid
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhujiang Hospital
COPD, Hypercapnic Respiratory Failure
Efficacy of High-intensity NPPV and Low-intensity NPPV in Patients With Chronic Hypercapnic COPD
High-intensity noninvasive positive pressure ventilation (NPPV), which can well improve the gas exchange and reduce the work of breathing of patients, is a new strategy targeted at maximally reducing arterial carbon dioxide.
- Trial name
- NPPV;COPD (NCT03238014)
- Testing
- Noninvasive positive pressure ventilation
- Where
- China
- Volunteers
- 14 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making
The goal of this research agenda is to improve the quality of end-of-life care by explicitly identifying values that will guide the decision-making process, with a particular emphasis on the role of ethnic, racial and cultural…
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Cirrhosis, Colon Carcinoma
- Trial name
- Aim3 (NCT00122135)
- Testing
- Values Inventory (VI)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
COPD
Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose Combination Nebuliser Solutions in Stable Chronic Obstructive Pulmonary Disease (COPD) Patients
The goal of this clinical trial is to compare the acute bronchodilator effect of the Ipratropium / Levosalbutamol 1.25 mg \& 0.5 mg / 2.5 mL fixed dose combination nebuliser solution or Levosalbutamol 1.25 mg / 3 mL nebuliser…
- Trial name
- NCT05890638
- Testing
- Ipratropium / Levosalbutamol Fixed Dose Combination, Ipratropium + Levosalbutamol Free Dose Combination
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
Chronic Obstructive Pulmonary Disease
14729-D9831C00002- 1 Month Biopsy Study
The purpose of this study is to study histological changes, cellularity, clinical efficacy and safety of AZD1981 in patients with Chronic Obstructive Pulmonary Disease
- Trial name
- Biopsy (NCT00766415)
- Testing
- AZD1981
- Where
- 8 sites in Germany, Netherlands and 1 more
- Volunteers
- 52 people
- Sponsor
- AstraZeneca
Multiple Conditions, Coronary Heart Disease
Improving Monitoring of Patients Receiving Case Management
The UK population is ageing and the likelihood of having a long term health condition increases with age. Three out of every five people over 60 in the UK have a long term condition.
- Conditions
- Multiple Conditions, Coronary Heart Disease, Diabetes, Hypertension
- Trial name
- NCT01597882
- Where
- 2 sites in United Kingdom
- Volunteers
- 114 people
- Sponsor
- University of Southampton
Pulmonary Disease, Chronic Obstructive
HandiHaler® vs. Metered Dose Inhaler (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Trial to compare the administration technique for HandiHaler® vs. MDI, to compare the learning retention of the administration technique for the HandiHaler® vs. MDI and to compare the ease of use for HandiHaler® vs. MDI
- Trial name
- NCT02172404
- Testing
- Ipratropium metered dose inhaler (MDI)
- Volunteers
- 160 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease, Anxiety
Dialogue Aimed at Reducing Anxiety in Patients With Severe COPD
The purpose of this trial is to determine whether a minimal homebased psychoeducative intervention is effective in management of anxiety and dyspnea in patients with severe chronic obstructive pulmonary disease.
- Trial name
- DIACOL (NCT02366390)
- Testing
- Psychoeducative intervention
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- Nordsjaellands Hospital
COPD (Chronic Obstructive Pulmonary Disease)
HFNC Versus NIV in Hypercapneic COPD Patients
Aim: To compare gas exchange trends, clinical outcomes, and tolerability between HFNC and NIV in COPD patients with mild-to-moderate hypercapnic respiratory failure.
- Trial name
- NCT07854210
- Testing
- high flow nasal cannula, non invasive ventilation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mohammed Shehta
Dyspnea, Chronic Obstructive Pulmonary Disease
The Effect of Music Therapy on Dyspnea Severity and Vital Signs
This study aims to investigate the effect of music therapy on dyspnea severity and quality of life indicators in patients with Chronic Obstructive Pulmonary Disease (COPD) admitted to the intensive care unit.
- Trial name
- NCT06358235
- Testing
- Music Therapy, No Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Suleyman Demirel University
Chronic Obstructive Pulmonary Disease
Expression of miR-204 and Consequences on Capillarization in Limb Muscles of Patients With COPD
Limb muscle dysfunction, characterized by loss of capillaries, is amongst the most troublesome systemic consequences of chronic obstructive pulmonary disease (COPD) leading to poor functional status and premature mortality.
- Trial name
- NCT02903043
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laval University
Pulmonary Disease, Chronic Obstructive
Prevalence of Chronic Obstructive Pulmonary Disease (COPD) and Eosinophilia Among Primary Care Patients
Early diagnosis and appropriate treatment for COPD subjects are both critical to minimize the progression of COPD and improve outcomes.
- Trial name
- NCT03018808
- Testing
- Minimal questionnaire, Medical interview, CAT
- Where
- 4 sites in Brazil
- Volunteers
- 800 people
- Sponsor
- GlaxoSmithKline
Parkinson Disease, Diabetes Mellitus
Health Indicators and Patient Reported Outcomes. Identification of Significative Items Aimed at Improving Health Care Procceses.
The objective of this study is to identify key indicators in the follow-up of subjects with different pathologies related to both the person's environment, as well as the perception of their health and general quality of life and…
- Conditions
- Parkinson Disease, Diabetes Mellitus, COVID-19, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- OUTCOMES (NCT05343962)
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Instituto de Biomecanica de Valencia
Pulmonary Disease, Chronic Obstructive
Study To Assess Efficacy and Safety of Oglemilast in Patients With Chronic Obstructive Pulmonary Disease (COPD)
This study will assess the safety and efficacy of a range of oglemilast doses. The study will be 14 weeks in duration. All patients meeting the eligibility criteria will be randomized to one of three doses of oglemilast or…
- Trial name
- NCT00671073
- Testing
- Oglemilast
- Where
- 47 sites in United States
- Volunteers
- 427 people
- Sponsor
- Forest Laboratories
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