Clinical trials: Chronic Obstr Lung Disease
Chronic Obstructive Pulmonary Disease
Pulmonary Microbiota in Patients With Chronic Obstructive Pulmonary Disease Colonized With P. Aeruginosa Resistant to Imipenem
Pseudomonas aeruginosa (PA ) is associated with chronic lung infections in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- MiPAD (NCT03008746)
- Testing
- water used for oral wash, sputum, oral wash
- Where
- France
- Volunteers
- 58 people
- Sponsor
- CHU de Reims
Hypoxemia, Gastric Cancer (Diagnosis)
High-Flow Nasal Cannula Oxygenation During Sedated Gastrointestinal Endoscopy in Patients With Chronic Obstructive Pulmonary Disease
Hypoxemia is the most common adverse event during propofol sedation for gastrointestinal endoscopy in patients with chronic obstructive pulmonary disease (COPD) due to diminished pulmonary reserve.
- Conditions
- Hypoxemia, Gastric Cancer (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD), Esophageal Cancer
- Trial name
- NCT07791979
- Testing
- High-flow nasal cannula
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhejiang University
Joint Osteoarthritis, Atherosclerosis of the Distal Arteries, Without Gangrene
Evaluation of Impaired Mobility in Chronic Illness Constitution of a Cohort
Chronic illness is a public health issue and mobility loss is frequent in this population. Among its' multiple physical and psychological consequences, increased mortality and cardiovascular morbidity seem the main concern.
- Conditions
- Joint Osteoarthritis, Atherosclerosis of the Distal Arteries, Without Gangrene, Parkinson Disease, Chronic Obstructive Pulmonary Disease, Unspecified
- Trial name
- EVALMOB (NCT04375280)
- Testing
- Development of a screening algorithm designed to determine a "dysmobility" profile in patients with chronic illness.
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pulmonary Disease, Chronic Obstructive
General Practice Quality Assurance Project. Chronic Obstructive Pulmonary Disease (COPD) Diagnosis and Treatment
A Cross sectional observational Quality Assurance Project in General Practice to COPD Diagnosis and Treatment
- Trial name
- NCT00319813
- Testing
- Education
- Volunteers
- 8,000 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Nutritional Risk and Diaphragmatic Thickness in Mechanically Ventilated COPD Patients
Malnutrition and muscle wasting are frequent complications in patients with chronic obstructive pulmonary disease (COPD) experiencing acute exacerbations.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Malnutrition, Respiratory Failure
- Trial name
- NCT07788170
- Volunteers
- 120 people
- Sponsor
- Assiut University
Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
Longitudinal Study of Cortisol and Pulmonary Function
To conduct a longitudinal study of the relationship between the rate of decline of pulmonary function and measurements of cortisol concentration and excretion in a sample of middle-aged and older men and their wives.
- Trial name
- NCT00005370
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Obstructive Pulmonary Disease
Change of Inspiratory Peak Flow in COPD
Chronic obstructive bronchitis and emphysema (COPD) are pathophysiologically characterized by inflammatory and structural changes in the lung.
- Trial name
- NCT00561886
- Testing
- Formoterol
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johannes Gutenberg University Mainz
Pulmonary Disease, Chronic Obstructive
(In)Voluntary Assessed Quadriceps Muscle Endurance in COPD
The primary objective is to assess the relation between involuntary and voluntary assessed quadriceps muscle endurance in patients with COPD. We hypothesized a good correlation (>0.8) between the measurements.
- Trial name
- Bionic (NCT05427773)
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Radboud University Medical Center
Chronic Obstructive Pulmonary Disease
Effects on PaCO2 Levels of Two Different Nasal Cannula in COPD Patients
High-flow nasal cannula (HFNC) therapy is increasingly used in the management of acute respiratory failure. Its clinical application has been expanded also in other specific settings In stable COPD patients and in those…
- Trial name
- CODUET (NCT05528289)
- Testing
- AIRVO 2, with conventional symmetric nasal cannula, AIRVO 2, the new asymmetric nasal cannula
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Chronic Obstructive Pulmonary Disease (COPD)
Long Term Safety Study of NVA237 vs QAB149 in COPD Patients
The purpose of the study is to provide long term safety data of NVA237. This study will assess the safety and tolerability of a single dose strength of NVA237.
- Trial name
- NCT01697696
- Testing
- NVA237, Long-acting beta 2-agonist (LABA)
- Where
- 61 sites in United States
- Volunteers
- 511 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD)
Short-Term Inspiratory Muscle Training and Aerobic Exercise in Women With COPD
Brief Summary: This randomized controlled trial evaluated the short-term effects of inspiratory muscle training, aerobic exercise, combined inspiratory muscle training and aerobic exercise, placebo inspiratory muscle training…
- Trial name
- IMT-COPD (NCT07604961)
- Testing
- Inspiratory Muscle Training, Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Mehmet İsmail TOSUN
Chronic Obstructive Pulmonary Disease
Balance Training for Chronic Obstructive Pulmonary Disease (COPD)
The study will involve direct knowledge translation of a laboratory-based study of balance training for patients with COPD, first to the investigators PR program and then, after disseminating the results, this approach could be…
- Trial name
- NCT02080442
- Testing
- Balance training
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Samantha Harrison
Emphysema, Lung Diseases
Emphysema: Physiologic Effects of Nutritional Support
To determine if enteral nutrition support (ENS) restores normal body weight and improves muscle strength, exercise performance, sensation of dyspnea, and quality of life in malnourished patients with chronic obstructive pulmonary…
- Conditions
- Emphysema, Lung Diseases, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00000573
- Testing
- enteral nutrition
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Obstructive Pulmonary Disease
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive)…
- Trial name
- THESEUS (NCT07190222)
- Testing
- Lunsekimig
- Where
- 314 sites in United States, Argentina and 24 more
- Volunteers
- 942 people
- Sponsor
- Sanofi
Medication Adherence, Self-care
The Supporting Patient Activation in Transition to Home Intervention
This study evaluates if motivational interviewing sessions aiming to motivate recently discharged patients with either chronic obstructive pulmonary disease or congestive heart failure to be active in post-discharge…
- Conditions
- Medication Adherence, Self-care, Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- [sPATH] (NCT02823795)
- Testing
- Motivational Interviewing
- Where
- 2 sites in Sweden
- Volunteers
- 118 people
- Sponsor
- Karolinska Institutet
Chronic Obstructive Pulmonary Disease
An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease
This study is investigating the possible mechanisms of action of an inhaled treatment (Seretide), currently used worldwide in millions of patients with COPD (Chronic Obstructive Pulmonary Disease) and how it improves the symptoms…
- Trial name
- IMAS (NCT00974805)
- Testing
- Seretide 500 Accuhaler
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Pulmonary Disease, Chronic Obstructive
Osteoprotegerin (OPG) in Induced Chronic Obstructive Pulmonary Disease (COPD) Sputum
Evaluation of OPG level as disease markers has also been reported. It has been showed that patients with coronary artery disease had higher serum OPG levels than healthy volunteers.
- Trial name
- NCT00655954
- Testing
- Induced sputum
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Imperial College London
COPD, Healthy Controls
Supramaximal High-Intensity Interval Training in People With and Without Chronic Obstructive Pulmonary Disease
Beyond pulmonary complications, COPD presents with extrapulmonary manifestations including reduced cognitive, cardiovascular, and muscle function.
- Trial name
- COPD-HIIT (NCT06068322)
- Testing
- Exercise training on a stationary bicycle
- Where
- 2 sites in Belgium, Sweden
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Umeå University
Chronic Obstructive Pulmonary Disease (COPD)
Preventing Repeat Hospitalisations in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to determine whether the investigators can predict which patients are at risk of a re-exacerbation of COPD within 30 and 90 days using changes in lung capacity during the initial exacerbation.
- Trial name
- INCA R-ACE (NCT02644772)
- Where
- Ireland
- Volunteers
- 207 people
- Sponsor
- Beaumont Hospital
COPD, Pulmonary Hypertension
Registry for Chronic Obstructive Pulmonary Disease With Pulmonary Hypertension in China
Pulmonary hypertension is a common complication of chronic obstructive pulmonary disease (COPD). It is reported that over half of COPD patients develop pulmonary hypertension.
- Trial name
- NCT03185572
- Where
- China
- Volunteers
- 1,708 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
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