Clinical trials: Chronic Obstr Lung Disease
COPD - Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation
Comprehensive Maintenance Program: a Health Haven for COPD in Lleida.The NAPOLEON Project.
Introduction: Pulmonary rehabilitation programs (PRPs) are known to reduce symptoms such as dyspnea and fatigue, while improving functional capacity and quality of life in individuals with chronic obstructive pulmonary disease…
- Conditions
- COPD - Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation, Randomised Controlled Trial
- Trial name
- NAPOLEON (NCT07394712)
- Testing
- Interdisciplinary intervention
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Asthma, Bronchospasm
Escalating and Cumulative-Dose Study of Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of A006
The main objective is to evaluate the bronchodilatory efficacy, safety and pharmacokinetic profiles of A006 (Albuterol Dry Powder Inhaler (DPI)), in comparison with those of an active control, Proventil-HFA (Albuterol Metered…
- Conditions
- Asthma, Bronchospasm, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT01189396
- Testing
- A006, Proventil-HFA
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Chronic Obstructive Pulmonary Disease
A Study Of ¹²⁹XE MRI To Assess Disease Progression In Patients With COPD Treated With Or Without Azithromycin And Standard-of-Care Medications
This study will test whether daily use of azithromycin will reduce the rate of exacerbations and improve lung ventilation and perfusion assessed by XE-MRI.
- Trial name
- NCT04353661
- Testing
- Azithromycin, HP xenon (¹²⁹XE)
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Genentech, Inc.
Chronic Obstructive Pulmonary Disease
Chest Wall Muscle Stretching and Acute Effects in Chronic Obstructive Pulmonary Disease
The study hypothesis is chest wall muscle stretching increase distribution of volume variation of thoracoabdominal wall and reduce electromyographic activity of respiratory muscles in patients with Chronic Obstructive Pulmonary…
- Trial name
- NCT01826669
- Testing
- Stretching
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Universidade Federal de Pernambuco
Pulmonary Disease, Chronic Obstructive
Batefenterol/Fluticasone Furoate in Treatment of Chronic Obstructive Pulmonary Disease
Batefenterol inhalation powder is currently under development as a fixed-dose combination with fluticasone furoate (FF) for the treatment of Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT02573870
- Testing
- Batefenterol + Fluticasone Furoate, Albuterol
- Where
- 10 sites in United States
- Volunteers
- 63 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Correlation Between Handgrip Strength and Air Trapping in Patients with Stable Chronic Obstructive Pulmonary Disease
The goal of this observational study is to investigate the relationship between handgrip strength and air trapping in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT06220851
- Testing
- Handgrip strength
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Thammasat University
Diabetes Mellitus (DM), Congestive Heart Failure (CHF)
Expanding Paramedicine in the Community
Initiatives aimed at reducing Emergency Department (ED) wait times and improved community health initiatives are major priorities in Canada.
- Conditions
- Diabetes Mellitus (DM), Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- EPIC (NCT02034045)
- Testing
- Community Paramedicine, Usual Care
- Where
- 4 sites in Canada
- Volunteers
- 467 people
- Sponsor
- Unity Health Toronto
Chronic Obstructive Pulmonary Disease
A COPD Quality Improvement Program（QIP）
QIP(Quality Improvement Programme) is a COPD quality improvement program in China. The initial step of this program is to set up the Quality Standards(QS) of COPD management in clinical practice, then embed Quality Standards into…
- Trial name
- QIP (NCT05638646)
- Testing
- Intervention group, control group
- Where
- China
- Volunteers
- 1,107 people
- Sponsor
- Shenzhen People's Hospital
Chronic Obstructive Pulmonary Disease
Unrefined Salmon Oil as Dietary Supplement in Patient With Chronic Obstructive Pulmonary Disease
Research has over decades showed that marine food carries nutritional characteristics that promote human health. As seen in epidemiological studies and based on in vitro and in vivo studies, it is hypothesized that unrefined…
- Trial name
- NCT05130294
- Testing
- CARDIO®
- Where
- Norway
- Sponsor
- Hofseth Biocare ASA
COPD, Chronic Obstructive Pulmonary Disease
GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD (Chronic Obstructive Pulmonary Disease) Screening?
This is a multicenter observational prospective study in smokers or ex-smokers with cumulative exposure ≥ 10 a / p (years / pack) with respiratory symptoms and presenting a normal spirometry.
- Trial name
- NCT05016466
- Testing
- Standard Care, Standard Care plus oxidative stress study plus inflammation biomarkers study
- Where
- Spain
- Volunteers
- 236 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Chronic Obstructive Pulmonary Disease
The Effects of Aerobic Exercise Training on Vascular, Cardiac and Cerebral Vascular Function in COPD
The primary cause of chronic obstructive pulmonary disease is smoking, which can lead to inflammation in the lungs and blood vessels that can lead to secondary problems such as blood vessel disease, high blood pressure and heart…
- Trial name
- NCT02875522
- Testing
- Individualized, non-linear aerobic exercise training
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Infection, Heart Failure
Prediction of Expected Length of Hospital Stay Using Machine Learning
This is a retrospective observational study drawing on data from the Brigham and Women's Home Hospital database. Sociodemographic and clinic data from a training cohort were used to train a machine learning algorithm to predict…
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04784351
- Where
- 2 sites in United States
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease, Glaucoma, Angle-Closure
Effect of Tiotropium on Eye Findings in the Treatment of Chronic Obstructive Pulmonary Disease
This study aimed to examine the effect of Tiotropium, which is used in the treatment of COPD, on eye symptoms.The study was conducted prospectively. Patients were examined in three groups.
- Trial name
- NCT06525051
- Testing
- Tiotropium
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Giresun University
Copd
The Association Between Blood Eosinophilsp in Thai COPD Patients: A Prospective Study
The association of blood eosinophil as a biomarker for eosinophilic Thai COPD patients, such as COPD exacerbation, hospital admission, lung functions and mortlity.
- Trial name
- NCT04123028
- Testing
- observatory
- Where
- Thailand
- Volunteers
- 145 people
- Sponsor
- Prince of Songkla University
Chronic Obstructive Pulmonary Disease (COPD), Mental Imagery
Motor Imagery in Chronic Obstructive Pulmonary Disease
The purpose of this study was to compare the motor imagery ability of individuals with Chronic Obstructive Pulmonary Disease (COPD) with those without COPD.
- Trial name
- NCT07171957
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Chronic Obstructive Pulmonary Disease
A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of TQC3302 Inhalation Spray in Healthy Adult Subjects
Groups 1, 3, 4, 5 and 6 of this research team adopted a single-center, open-label design. Group 2 used a three-sequence, three-period crossover design, where participants in this dose group were randomly assigned to the three…
- Trial name
- NCT07267130
- Testing
- TQC3302 inhalation spray, TQC3302 inhalation spray+Tiotropium bromide and olodaterol hydrochloride inhalation spray +Budesonide Powder for Inhalation, Tiotropium bromide and olodaterol hydrochloride inhalation spray +Budesonide Powder for Inhalation+ TQC3302 inhalation spray
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical (Guangzhou) Co., Ltd.
Chronic Obstructive Pulmonary Disease (COPD)
Educational Interventions for Chronic Obstructive Pulmonary Disease (COPD) Self-management in Ethno-cultural Communities
Goal: The main goal of this study is to develop and validate educational materials that aim to improve self-management knowledge and practices about COPD among patients in Mandarin and Cantonese-speaking communities in the…
- Trial name
- COPD (NCT01474707)
- Testing
- Group one, Group two, Group three
- Where
- 2 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Severe Chronic Obstructive Pulmonary Disease, Dyspnea
The Effectiveness Pulmonary Telerehabilitation and Cognitive Telerehabilitation in COPD Patients
The aim of our study is to compare the effectiveness of the supervized pulmonary telerehabilitation program and the cognitive telerehabilitation method, which includes pulmonary telerehabilitation methods, in patients with severe…
- Conditions
- Severe Chronic Obstructive Pulmonary Disease, Dyspnea, Muscle Weakness, Fatigue
- Trial name
- NCT05222295
- Testing
- Supervised Pulmonary Telerehabilitation, Cognitive Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Saglik Bilimleri Universitesi
Respiratory Disease Undergoing Elective Bronchoscopy., Chronic Obstructive Pulmonary Disease
Safety and Benefits of Using Laryngeal Mask Airway to Keep Airway Potency During Fiber-optic Bronchoscopy
Bronchoscopy is a method of diagnosis and treatment of common respiratory diseases and lung recognized for many years. Since the action takes place in the airways and in light of the use of sedation, when performing, the…
- Trial name
- NCT02698007
- Testing
- Laryngeal Mask Airway (LMA)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Breathing Exercise, Breathing Technique
Effectiveness of Balloon Blowing and Deep Breathing Exercise on Increasing Peripheral Oxygen Saturation in Patients With Chronic Obstructive Pulmonary Disease
This study aims to determine the effect of Balloon Blowing and Deep Breathing Exercise on Increasing Peripheral Oxygen Saturation in Patients with Chronic Obstructive Pulmonary Disease. The main question it aims to answer is: 1.
- Trial name
- NCT07646002
- Testing
- Balloon-blowing and Deep breathing exercises, Deep breathing exercises
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
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