Clinical trials: Chronic Obstr Lung Disease
COPD (Chronic Obstructive Pulmonary Disease), Artificial Intelligence
A Prospective, Multicenter, Portable Pulmonary Function Comparison Study Aimed at Evaluating the External Clinical Validation of the Chronic Obstructive Pulmonary Disease Auxiliary Diagnostic Software LH-002 (Version: 2.0.0) in Clinical Diagnosis Accuracy
Chronic Obstructive Pulmonary Disease (COPD) is widely underdiagnosed in low- and middle-income countries and regions, due to the lack of accessible tools.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Artificial Intelligence, Cough, Diagnosis
- Trial name
- NCT07888712
- Where
- China
- Volunteers
- 466 people
- Sponsor
- Ruijin Hospital
COPD
Study of Arformoterol Tartrate Inhalation Solution and Racemic Formoterol in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to compare the blood levels of arformoterol tartrate inhalation solution to racemic formoterol in male and female subjects with mild to moderate Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT00685529
- Testing
- Racemic formoterol, Arformoterol tartrate inhalation solution
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- Sumitomo Pharma America, Inc.
COPD
Long-term Oxygen Therapy in Patients With Chronic Obstructive Pulmonary Disease Who Live at High Altitude
A clinical, prospective, randomized controlled trial to determine the effect of prescribing oxygen in a group of COPD (chronic pulmonary disease) patients with PaO2 (arterial oxygen tension) ≥50 and ≤55 mmHg who do not have…
- Trial name
- COPD-LTOT (NCT03020212)
- Testing
- Oxygen
- Where
- Colombia
- Volunteers
- 220 people
- Sponsor
- Fundación Neumologica Colombiana
Pulmonary Disease, Chronic Obstructive
Analyzing Lung Tissue in People With and Without Chronic Obstructive Pulmonary Disease Who Are Undergoing Lung Transplantation
Chronic obstructive pulmonary disease (COPD) is a long-term lung disease. People with COPD have difficulty breathing because of lung damage.
- Trial name
- NCT00756522
- Testing
- There is no intervention. Study is observational.
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Washington University School of Medicine
Pulmonary Disease, Chronic Obstructive
Respimat® Combivent Trial in Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to compare the effect of ipratropium bromide/salbutamol inhalation spray combination administered by the Respimat® inhaler (20 mcg/100 mcg), ipratropium bromide inhalation spray administered…
- Trial name
- NCT00400153
- Testing
- Atrovent Respimat (20 mcg), COMBIVENT MDI (36/206 mcg), Combivent Respimat (20 mcg/100 mcg)
- Where
- 180 sites in United States, Argentina and 11 more
- Volunteers
- 1,480 people
- Sponsor
- Boehringer Ingelheim
Dynamic Lung Hyperinflation, COPD Patients
Daily Activities Are Sufficient to Induce Dynamic Pulmonary Hyperinflation and Dyspnea in Chronic Obstructive Pulmonary Disease Patients
Introduction: Chronic obstructive pulmonary disease is a condition characterized by airflow limitation usually progressive and associated with inflammatory response of lung noxious particles.
- Conditions
- Dynamic Lung Hyperinflation, COPD Patients, Activities of Daily Livin.
- Trial name
- Hyperinflation (NCT01475812)
- Testing
- Hyperinflation and ADL
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Federal University of São Paulo
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the 24 Hour Spirometric Effect (FEV1) of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate (FF)/25mcg Vilanterol (VI)) Compared With Salmeterol/Fluticasone Propionate Inhalation Powder (50mcg Salmeterol/500mcg Fluticasone Propionate (FP))
The purpose of this study is to evaluate the 24-hour spirometry effect (FEV1) of Fluticasone Furoate/Vilanterol 100/25mcg once daily compared with Salmeterol/Fluticasone Propionate 50/500mcg twice daily over a 12-week treatmen…
- Trial name
- NCT01342913
- Testing
- Fluticasone Furoate 100mcg/Vilanterol 25mcg, Fluticaosne Propionate 500mcg/Salmeterol 50mcg
- Where
- 66 sites in Belgium, France and 7 more
- Volunteers
- 528 people
- Sponsor
- GlaxoSmithKline
Pulmonary Disease, Chronic Obstructive
To Evaluate the Effect of Inhaled Medication Together With Exercise and Activity Training on Exercise Capacity and Daily Activities in Patients With Chronic Lung Disease With Obstruction of Airways
The primary objectives of the study are to explore the effect of treatment with orally inhaled tiotropium + olodaterol fixed dose combination with and without exercise training, and tiotropium comparing to placebo, on top of…
- Trial name
- NCT02085161
- Testing
- tiotropium+olodaterol, tiotropium +olodaterol, tiotropium
- Where
- 34 sites in United States, Australia and 9 more
- Volunteers
- 304 people
- Sponsor
- Boehringer Ingelheim
COPD
TELE-monitoring in Chronic Obstructive Pulmonary Disease
COPD is the fourth cause of death worldwide and it is expected to be the third in 2020. Non-invasive ventilation (NIV) has a positive impact in reducing mortality related to chronic respiratory failure in stable patients with…
- Trial name
- TELECOPD (NCT03129477)
- Testing
- Telemonitoring in noninvasive ventilation
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Conde, Bebiana, M.D.
Dyspnea, Quality of Life
STRETCH OF RESPIRATORY MUSCLES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
THE AIM OF THIS STUDY IS TO TEST IF THE STRETCHING OF THE RESPIRATORY ACCESSORY MUSCLE PROVIDE SOME BENEFIT ON THORACOABDOMINAL MECHANICS, FUNCTIONAL CAPACITY, PSYCHOLOGICAL AND SOCIAL ASPECTS IN PATIENTS WITH CHRONIC OBSTRUCTIVE…
- Conditions
- Dyspnea, Quality of Life, Respiratory Symptoms
- Trial name
- NCT02036762
- Testing
- Stretching Exercises
- Where
- 3 sites in Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Chronic Obstructive Pulmonary Disease
Evaluation of an AR-Assisted System for Standardizing Spirometry
Spirometry is the gold-standard tool for diagnosing Chronic Obstructive Pulmonary Disease (COPD). However, its implementation in primary care is often limited by a shortage of qualified technicians and inconsistent testing…
- Trial name
- NCT07440420
- Testing
- AR-Assisted Spirometry Guidance System, Routine Technician-led Spirometry Guidance
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
COPD
The Effect of QVAR on Lung Functioning in Chronic Obstructive Pulmonary Disease
This is an investigator-sponsored research study to evaluate if treatment with HFA-134a beclomethasone (QVAR) has an effect on peripheral (or outer) airway inflammation and airway "remodeling" or scarring in subjects with COPD.
- Trial name
- NCT00238082
- Testing
- HFA-134A Beclomethasone DIpropionate (QVAR)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Jewish Health
Chronic Obstructive Pulmonary Disease
A Study to Assess the PK and Safety of PT010 in Subjects With COPD Following Single and Repeat Dose
This is a Phase I open-label, single center study to assess the PK and safety of BGF MDI 320/14.4/9.6 µg in subjects with moderate to severe COPD.
- Trial name
- NCT03250182
- Testing
- PT010
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Pearl Therapeutics, Inc.
Chronic Obstructive Pulmonary Disease
Outpatient Management of Patients With Exacerbation of Chronic Obstructive Pulmonary Disease
Patients admitted to the hospital with chronic obstructive pulmonary disease are evaluated with regard to early follow-up by a specialized nurse in the home after discharge.
- Trial name
- NCT00317057
- Testing
- Patient education and disease management
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Glostrup University Hospital, Copenhagen
COPD, Healthy
Femoral Artery Blood Flow During Rest and One-leg Knee Extensor Exercise in Patients With COPD
Doppler ultrasound is generally considered to provide reliable femoral blood flow measurements between rest and exercise, and the blood flow response to exercise is widely believed to be reduced in patients with chronic…
- Conditions
- COPD, Healthy, Chronic Obstructive Pulmonary Disease
- Trial name
- COPD-DOPPLER (NCT06135701)
- Testing
- One-legged knee-extensor exercise with Doppler measurements
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Asthma, Chronic Obstructive Pulmonary Disease
Towards Restoring the Physiological Inhibition of Airway Narrowing in Asthma
Asthma and COPD are characterized by airway narrowing. The most potent, physiological mechanism leading to bronchodilation is taking a deep inspiration.
- Trial name
- NCT00279136
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Chronic Obstructive Pulmonary Disease
Clinical Trial Assessing the Value of an Antibiotic Protocol Guided by Serum Procalcitonin in Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care
Investigators propose to conduct a prospective, randomized, controlled, multicenter assessing the interests of an antibiotic protocol guided by serum procalcitonin (PCT) on morbidity and mortality in patients with chronic…
- Trial name
- BPCTréa (NCT02521636)
- Testing
- Antibiotic therapy randomization, Serum PCT dosage
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Exercise Order During Pulmonary Rehabilitation on Muscle Strength in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a chronic multisystem disease frequently associated with peripheral muscle dysfunction, which is strongly linked to prognosis and survival.
- Trial name
- ISTOR-COPD (NCT07655011)
- Testing
- Pulmonary Rehabilitation - Strength First, Pulmonary Rehabilitation - Endurance First
- Where
- France
- Volunteers
- 138 people
- Sponsor
- CHU de Reims
Chronic Obstructive Pulmonary Disease, Foot Deformities
The Effect of Foot Deformities on Physical Activity, Fatigue Level and Quality of Life in Elderly COPD Patients
The aim of this study is to investigate the effects of changes in foot structure on physical activity level, fatigue and quality of life in COPD patients.
- Conditions
- Chronic Obstructive Pulmonary Disease, Foot Deformities, Quality of Life, Activity, Motor
- Trial name
- NCT04627935
- Testing
- The COPD Assessment Test, Navicular Drop Test, International Physical Activity Questionnaires (IPAQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Chronic Obstructive Pulmonary Disease
CHARM-COPD Program of Care
The investigators' goal for this project is to evaluate the feasibility, acceptability, and actual usage of a program of care for patients with COPD recently discharged after an acute exacerbation.
- Trial name
- NCT06253013
- Testing
- Hyfe Smartwatch, FitBit Versa 2, Home Spirometer
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.