Clinical trials: Chronic Obstr Lung Disease
Chronic Obstructive Pulmonary Disease
A Home-based Intervention to Promote Mindful Breathing Awareness Through Pursed-lip Breathing Training for COPD Patients
The Mindful Breathing Laboratory under the direction of Dr. Benzo will complete a randomized controlled trial to evaluate the mindful breathing module.
- Trial name
- NCT05349123
- Testing
- Mindful Breathing, Home-Based Pulmonary Rehabilitation
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Minnesota HealthSolutions
Chronic Obstructive Pulmonary Disease
Small Bioactive Molecules in Early COPD Diseases
To study the predictors contribute to the progression of COPD by follow-up of patients with early COPD and analyze their changes in bioactive molecular, exhaled gas, CT image, lung function, patient's symptoms and life quality.
- Trial name
- NCT04950023
- Where
- China
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Impact of Switching COPD Patients From Inhaler Devices to the Omron C28P Nebuliser.
The cornerstone of COPD therapy is based on the use of inhalation drugs. The correct use of devices is crucial; a suboptimal use technique is the cause of a possible clinical deterioration with a consequent increase in…
- Trial name
- OMRON (NCT06061679)
- Testing
- Omron C28P nebuliser
- Volunteers
- 99 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
COPD
Mechanical Properties of Peripheral and Accessory Respiratory Muscles in Chronic Obstructive Pulmonary Disease Patients
The biomechanical properties of accessory respiratory muscles and peripheral muscles of COPD and healthy subjects will be measured and compared with the MyotonPro device.
- Trial name
- NCT06201403
- Testing
- Determination of biomechanical properties of muscles
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul Medipol University Hospital
Nontuberculous Mycobacteria, Bronchiectasis
Evaluation Of The Lung Microbiome In NTM Bronchiectasis
A biomarker cohort study design is proposed to study whether specific airway microbiota alterations are associated with pulmonary Non-tuberculous mycobacteria (NTM) disease.
- Trial name
- NCT02779478
- Testing
- Bronchoscopy
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- NYU Langone Health
COPD Exacerbation
Extracorporeal Carbon Dioxide Removal in Severe Chronic Obstructive Pulmonary Disease Exacerbation
The conventional treatment for Severe acute exacerbation of Chronic obstructive pulmonary disease including noninvasive respiratory support, invasive respiratory support, etc, but there are many kinds of limitations and…
- Trial name
- NCT03692117
- Testing
- Extracorporeal Carbon Dioxide Removal
- Where
- China
- Volunteers
- 30 people
- Sponsor
- China-Japan Friendship Hospital
Chronic Obstructive Pulmonary Disease, End-of-Life Fear
End-of-Life Fear in Patients With End-Stage Lung Disease (COPD)
The aim of the study is to develop an interview to ask patients with COPD about their fear of death and dying, their needs and wishes at the end-of-life.
- Conditions
- Chronic Obstructive Pulmonary Disease, End-of-Life Fear, Fear About Death and Dying, Depression
- Trial name
- NCT00792974
- Testing
- A brief psycho-educational intervention
- Where
- 2 sites in Germany
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Obstructive Chronic Pulmonary Disease, Emphysema
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype
AIM: To identify those mechanisms involved in the systemic and muscular response to exercise treatment, in two different Obstructive Chronic Pulmonary Disease (COPD) phenotypes (emphysema and non-emphysema).
- Conditions
- Obstructive Chronic Pulmonary Disease, Emphysema, Chronic Bronchitis
- Trial name
- NCT01431625
- Testing
- Combined Training (endurance and strength exercises)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Heart Failure, Chronic Obstructive Lung Disease
Primary Care Management/Action Plans for Advanced Chronic Diseases
Patients living with advanced chronic diseases (ACD), such as congestive heart failure (CHF) and chronic obstructive lung disease (COPD) present substantial care and economic challenges for the health care system due to frequent…
- Trial name
- NCT00202150
- Testing
- Application of a management action plan
- Where
- Canada
- Volunteers
- 139 people
- Sponsor
- Queen's University
Chronic Obstructive Pulmonary Disease
A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) With a Next-Generation Propellant (NGP) With a Spacer, BGF MDI Hydrofluoroalkane (HFA) With a Spacer, as Well as BGF MDI NGP Without a Spacer
This study aims to assess the effect on total systemic exposure and to characterize exposure BGF MDI HFO with a spacer compared to without a spacer; also, to demonstrate that total systemic exposure of BGF when administered as…
- Trial name
- NCT06297668
- Testing
- Treatment A: BGF MDI HFA, Treatment B: BGF MDI HFO, Treatment C: BGF MDI HFO
- Where
- Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease Severe
A Decision Aid on End-of-life Care for Patients With Advanced COPD and Their Family
This study aims to support EOL decision-making in patients with advanced COPD and their family members. A parallel two-arm single-blinded randomised controlled trial will be conducted to evaluate the effects of a specific…
- Trial name
- NCT06008210
- Testing
- Decision Support Intervention, Health Coaching
- Where
- 2 sites in China
- Volunteers
- 226 people
- Sponsor
- Food and Health Bureau, Hong Kong
Chronic Obstructive Pulmonary Disease
Treatment in Patients Hospitalized With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease has become a serious global health care and public health problems due to its high prevalence, high morbidity and heavy economic burden.
- Trial name
- TripAE (NCT02219360)
- Volunteers
- 400 people
- Sponsor
- Beijing Chao Yang Hospital
Pulmonary Disease, Chronic Obstructive
Life-long Monitoring of COPD in Veneto Region
The purpose of this study is to evaluate whether the introduction of large-scale telemonitoring of patients with COPD produces benefits in terms of improved health-related quality of life and reduced access to hospital…
- Trial name
- NCT01513980
- Testing
- self-monitoring for patients with severe COPD, nurse-monitoring for patients with severe COPD
- Where
- 6 sites in Italy
- Volunteers
- 750 people
- Sponsor
- Regione Veneto
Chronic Obstructive Pulmonary Disease, Self Efficacy
The Effect of Training Given to Patients With COPD in Line With Pender's Health Promotion Model
This study was conducted as a randomized controlled experimental study. The study was conducted with patients hospitalized in the chest diseases intensive care unit of a state hospital.
- Trial name
- NCT06551103
- Testing
- Intervention group trained in line with the Health Promotion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Chronic Obstructive Pulmonary Disease
A Personalized Mobile Application Providing Temperature-Related Health Risk Warnings and Protective Recommendations for Patients With Chronic Obstructive Pulmonary Disease
This study will test whether a personalized mobile application that provides temperature-related health risk warnings and protective recommendations can reduce acute exacerbations in people with chronic obstructive pulmonary…
- Trial name
- NCT07656142
- Testing
- Mobile Application-Based Personalized Temperature Health Risk Early Warning Intervention
- Where
- 4 sites in China
- Volunteers
- 240 people
- Sponsor
- Tiantian Li
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Lung Tissue Research Consortium
The LTRC will facilitate histopathological research of pulmonary diseases by collecting lung tissues from donors and preparing and distributing collections of tissue specimens to researchers within and outside the LTRC.
- Trial name
- LTRC (NCT02988388)
- Testing
- Lung biopsy/lobectomy
- Where
- 4 sites in United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetic (PK), and Pharmacodynamic (PD) Profiles of 3 Doses of Fluticasone Furoate (FF)/GW642444 Inhalation Powder at the End of a 28-day Treatment Period in Subjects With Chronic Obstructive Pulmonary Disease (COPD) Compared to Placebo
The Purpose of this study is to evaluate the 24-hour spirometry effect Forced Expiratory Volume in One second (FEV1) of 3 doses of Fluticasone Furoate (FF)/GW642444 Inhalation Powder at the end of a 28-day treatment period in…
- Trial name
- NCT01072149
- Testing
- Fluticasone Furoate (FF)/GW642444 Inhalation Powder
- Where
- 8 sites in United States
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
A Double-blind, Placebo-controlled, Crossover Study to Assess the Effect of Aclidinium Bromide 400 μg Bid on COPD Symptoms and Sleep Quality After 3 Weeks of Treatment in Patients With Stable Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to assess the effect of aclidinium bromide compared with placebo in improving dilatation of the airways (bronchodilation), symptoms of chronic obstructive pulmonary disease (COPD), sleep quality and…
- Trial name
- NCT02153489
- Testing
- Aclidinium bromide
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Muscle Dysfunction in Patients With Chronic Obstructive Lung Disease (COPD): the Role of Sympathetic Activation
The objective of the project is to better understand the causes of exercise limitation, dyspnea and neurohumoral activation in patients with COPD.
- Trial name
- NCT01750489
- Testing
- non-invasive ventilation (NIV)
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Chronic Obstructive Pulmonary Disease (COPD)
Management of Patients With Respiratory Symptoms in Sweden
This is a web-based randomized survey to evaluate management of respiratory symptoms among physicians in Sweden. The aim of this study is to determine if there is a gender bias in the diagnosis of COPD and how often physicians…
- Trial name
- NCT02728674
- Testing
- Person in the case is a male., Person in the case is a female., Symptom in the case is breathlessness.
- Where
- Sweden
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
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