Clinical trials: Chronic Obstruct Airways Disease
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Chronic Obstructive Pulmonary Disease
Indoor Air Quality and Respiratory Symptoms in Former Smokers
The investigators will conduct a randomized, controlled, double-blind, crossover trial to determine whether the presence of a portable high-efficiency indoor air filter in the bedroom reduces respiratory symptoms in former…
- Trial name
- NCT02956213
- Testing
- HEPA portable air filter
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Intermountain Health Care, Inc.
Chronic Obstructive Pulmonary Disease
CHARM-COPD Program of Care
The investigators' goal for this project is to evaluate the feasibility, acceptability, and actual usage of a program of care for patients with COPD recently discharged after an acute exacerbation.
- Trial name
- NCT06253013
- Testing
- Hyfe Smartwatch, FitBit Versa 2, Home Spirometer
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Chronic Obstructive Pulmonary Disease, Balance
Investigation of Impairments in Body Functions and Structures, Activities and Participation Restrictions in COPD
This cross-sectional study aims to investigate to the impairments in body functions and structures, activities and participation restrictions according to the International Classification of Functioning, Disability and Health…
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance, Activity, Motor, Participation, Patient
- Trial name
- NCT05632120
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Obstructive Pulmonary Disease
Examination of Acute Effects of Different Intensity Respiratory Muscle Training on Respiratory Muscle Activations
It has been observed in the literature that respiratory muscle electromyography activations at certain threshold loads have been examined in individuals with chronic obstructive pulmonary disease.
- Trial name
- NCT04974788
- Testing
- Low Intensity Respiratory Muscle Training, Medium Intensity Respiratory Muscle Training, High Intensity Respiratory Muscle Training
- Volunteers
- 20 people
- Sponsor
- Abant Izzet Baysal University
Copd
Eccentric Training in Individuals With COPD
Skeletal muscle dysfunction as a systemic consequence of chronic obstructive pulmonary disease (COPD) has a major impact on quality of life, health care resource utilization, and mortality of patients with this disease.
- Trial name
- NCT04785469
- Testing
- Low-load eccentric training, Usual care
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Pulmonary Disease, Chronic Obstructive
Effects of Once Daily Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD) of Different Severity
The primary objective of this study is to investigate the effect of tiotropium vs. placebo on trough FEV1 and FEV1 2 hours post inhalation after 12 weeks of treatment. For both endpoints changes from baseline will be analysed.
- Trial name
- NCT00274573
- Testing
- Tiotropium bromide
- Where
- 177 sites in Germany
- Volunteers
- 1,639 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-06)
The aim of the study is to investigate the effect of roflumilast (APTA-2217) on lung function in patients with chronic obstructive pulmonary disease (COPD). Roflumilast will be administered orally once daily.
- Trial name
- NCT00242294
- Testing
- Roflumilast
- Where
- Japan
- Volunteers
- 570 people
- Sponsor
- AstraZeneca
COPD, Postural; Defect
Spinal Structure and Mobility in Chronic Obstructive Pulmonary Disease
In recent studies with musculoskeletal system disorders in chronic respiratory patients, it has been reported that postural control is affected in COPD patients.
- Conditions
- COPD, Postural; Defect, Respiratory Function Impaired, Dyspnea
- Trial name
- NCT05021068
- Testing
- Postural Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Izmir Katip Celebi University
Chronic Obstructive Pulmonary Disease
Erdosteine (Erdotin) Versus Standard Care Plus Placebo on Erdosteine for Treatment of Cough in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
This is a parallel group, double-blind, placebo controlled, multi-centre, randomised trial. 60 patients to be included who are adult patients admitted to hospital with a clinical diagnosis of acute exacerbation of Chronic…
- Trial name
- NCT01176318
- Testing
- Erdosteine
- Where
- United Kingdom
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Pulmonary Disease, Chronic Obstructive
Tiotropium in the Treatment of the Patients With Chronic Obstructive Pulmonary Disease
To collect post-marketing safety and effectiveness information on the use of Tiotropium Inhalation Capsules (18 μg) in patients with chronic obstructive pulmonary disease in daily clinical settings
- Trial name
- COPD (NCT02177318)
- Testing
- Spiriva (tiotropium bromide) inhalation capsules
- Where
- 418 sites in Japan
- Volunteers
- 3,588 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Safety and Efficacy of Multiple Doses of QAX028 in Chronic Obstructive Pulmonary Disease (COPD) Patients
This study will assess the bronchodilator effects of multiple doses of QAX028 at two different dose levels when compared to tiotropium and placebo in a COPD population.
- Trial name
- NCT01068613
- Testing
- QAX028, Tiotropium
- Where
- 4 sites in United States
- Volunteers
- 62 people
- Sponsor
- Novartis Pharmaceuticals
COPD
A Study to Investigate Using Inhaled Fexlamose to Treat Adult Participants Who Have Moderate to Severe COPD
AER-01-002 is a Phase 2a study being conducted to determine if inhaled fexlamose is an effective and safe treatment for adults with moderate to severe COPD. Study will compare active drug to placebo.
- Trial name
- AER-01-002 (NCT06731959)
- Testing
- Flexlamose
- Volunteers
- 100 people
- Sponsor
- Aer Therapeutics
Pulmonary Emphysema
Video Assisted Thoracic Surgery (VATS) Fissure Completion Prior to Zephyr® Endobronchial Valve Insertion
Prospective, multi-centre, pilot study aimed to evaluate the effect of Video Assisted Thoracic Surgery (VATS) fissure completion on the efficacy of endobronchial valve insertion (Zephyr Valve) in the treatment of subjects with…
- Trial name
- COVE (NCT04465461)
- Testing
- Video-assisted thoracoscopic surgery (VATS) fissure completion, Zephyr Valve insertion
- Where
- 2 sites in Australia
- Volunteers
- 9 people
- Sponsor
- Pulmonx Corporation
Chronic Obstructive Pulmonary Disease Severe
Ventilatory Adaptation to Concentric Versus Eccentric Exercise in Patients With Severe COPD
Pulmonary rehabilitation (PR) based on concentric exercise training has become an integral component in the treatment of patients with chronic obstructive pulmonary disease (COPD), improving functional capacities while…
- Trial name
- CONvEX (NCT03923660)
- Testing
- Incremental Concentric-eccentric exercise test, Incremental Eccentric-concentric exercise test
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Obstructive Pulmonary Disease (COPD)
Readmissions to Hospital Among Patients With COPD After Telemedicine Video Consultation - a Pilot Project
The purpose of this study was to evaluate the effects of telemedicine video-consultation (TVC) on the frequency of hospital re-admissions during 12 months follow-up after TVC among patients with chronic obstructive pulmonary…
- Trial name
- NCT02006082
- Testing
- Telemedicine video-consultation (TVC)
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Helse Stavanger HF
Chronic Obstructive Pulmonary Disease
Health Literacy in People With Chronic Obstructive Pulmonary Disease
Health literacy refers to personal and relational factors affecting a person's ability to acquire, understand and use information about health and health services.
- Trial name
- NCT03216603
- Testing
- Health literacy intervention group
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Lovisenberg Diakonale Hospital
Pulmonary Disease, Chronic Obstructive
Japan Long-term Safety for Tiotropium Plus Olodaterol
The primary objective of this study is to assess the safety of 52 weeks once daily treatment with orally inhaled tiotropium + olodaterol FDC and olodaterol (delivered by the RESPIMAT Inhaler) in Japanese patients with Chronic…
- Trial name
- NCT01536262
- Testing
- Tiotropium + Olodaterol, Respimat, Olodaterol
- Where
- 24 sites in Japan
- Volunteers
- 122 people
- Sponsor
- Boehringer Ingelheim
Copd
Efficacy of Osteopathic Manipulative Techniques in Patients With Chronic Obstructive Pulmonary Disease
This study will test the efficiency of rib rising technique and thoracic lymphatic pump technique combining with manual diaphragmatic release technique in patients with chronic obstructive pulmonary disease
- Trial name
- NCT06865703
- Testing
- diaphragmatic release technique, rib raising technique in group A, THORACIC LYMPHATIC PUMP TECHNIGUE
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Beni-Suef University
Chronic Obstructive Pulmonary Disease (COPD)
A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of KIT2014 in Patients With Moderate to Severe COPD
Study investigating the safety, tolerability, pharmacokinetics and early efficacy with KIT2014 over 7 days of treatment in moderate to severe chronic obstructive pulmonary disease patients.
- Trial name
- NCT07668518
- Testing
- KIT2014
- Where
- 3 sites in Australia
- Volunteers
- 36 people
- Sponsor
- Kither Biotech Srl
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