Clinical trials: Chronic Obstruct Airways Disease
Cystic Fibrosis, Chronic Obstructive Pulmonary Disease (COPD)
Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Women with chronic lung disease characterised by chronic cough report urinary incontinence. Recently there have been reports of increased urinary incontinence in girls and women with cystic fibrosis.
- Trial name
- NCT00164138
- Testing
- Pelvic floor training group
- Where
- 2 sites in Australia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Chronic Obstructive Pulmonary Disease
BACE Trial Substudy 2 - FarmEc Substudy
A second sub-analysis of the BACE trial will include a detailed cost-effectiveness study.
- Trial name
- FarmEc (NCT02205255)
- Testing
- Azithromycin
- Where
- 20 sites in Belgium
- Volunteers
- 350 people
- Sponsor
- Wim Janssens
Chronic Obstructive Pulmonary Disease
Study to Evaluate Efficacy/Safety of Combination Budesonide/Indacaterol vs Fluticasone/Salmeterol in Patients With COPD
To demonstrate the free combination of budesonide and indacaterol is as efficacious as fluticasone and salmeterol in patients with COPD
- Trial name
- COMBINE (NCT02055352)
- Testing
- Budesonide, Fluticasone, Indacaterol
- Where
- 25 sites in Argentina, Brazil and 6 more
- Volunteers
- 222 people
- Sponsor
- Novartis Pharmaceuticals
HRV and RSV Presence in the Lungs of Stable COPD Patients.
Viral Infections in BAL and Bronchial Biopsies of Stable COPD Patients
Background: The presence of low-grade viral infection in the airways of patients with stable chronic obstructive pulmonary disease (COPD) could potentially have implications in the pathogenesis and progression of the disease, but…
- Trial name
- NCT02622009
- Testing
- BRONCHOSCOPIC PROCEDURE
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Athens
Congestive Heart Failure, Asthma
Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases
In this project, Institute of Bioengineering \& Bioimaging (IBB), A*STAR would like to collaborate with Massachusetts General Hospital to aggregate patient data and to further develop its software algorithm using machine learning…
- Conditions
- Congestive Heart Failure, Asthma, Chronic Obstructive Pulmonary Disease, Cystic Fibrosis
- Trial name
- NCT04825067
- Testing
- Respiratory Sensor measurements
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Institute of Bioengineering and Bioimaging (IBB)
COPD (Chronic Obstructive Pulmonary Disease)
Photon-counting CT in Chest Imaging
Purpose and objective: This project aims to evaluate photon-counting computed tomography (PCCT) quantitative accuracy using COPDGene subjects.
- Trial name
- NCT07031336
- Testing
- Photon-counting CT, Energy-integrating CT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Chronic Obstructive Pulmonary Disease (COPD)
Management of Patients With Respiratory Symptoms in Sweden
This is a web-based randomized survey to evaluate management of respiratory symptoms among physicians in Sweden. The aim of this study is to determine if there is a gender bias in the diagnosis of COPD and how often physicians…
- Trial name
- NCT02728674
- Testing
- Person in the case is a male., Person in the case is a female., Symptom in the case is breathlessness.
- Where
- Sweden
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Chronic Obstructive Pulmonary Disease
Functional Respiratory Imaging Study (FRI)
The purpose of this study is to evaluate the effect of inhaled extrafine CHF5993 pMDI on airway volumes, and resistance, by Functional Respiratory Imaging (FRI), in COPD patients
- Trial name
- FRI (NCT03268226)
- Testing
- Beclometasone dipropionate/Formoterol Fumarate/Glycopyrronium
- Where
- 5 sites in Belgium, Hungary
- Volunteers
- 20 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema
Volumetric HRCT in Stable COPD Patients.
This study evaluates the role of volumetric high-resolution computed tomography (HRCT) of the chest in assessing patients with stable chronic obstructive pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema, Airway Obstruction
- Trial name
- NCT07809399
- Testing
- Volumetric HRCT chest, Spirometry and Body Plethysmography
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Patient Adherence
Efficacy Of An Education Plan And Adherence Follow-Up To The Exercise In Patients With COPD
Chronic obstructive pulmonary disease is one of the main causes of morbidity and mortality worldwide, according to recent publications of the World Health Organization, its main feature is the response to noxious particles of…
- Trial name
- NCT05204498
- Testing
- Education plan and adherence to exercise
- Where
- Colombia
- Volunteers
- 31 people
- Sponsor
- Clínica de Occidente S.A
Chronic Obstructive Pulmonary Disease
Racial Inequality in Inhaler Fills for COPD - A Trial of Reduced Cost-Sharing
In partnership with a large Medicare Advantage (MA) insurer (Humana, Inc.) and as part of a Center for Medicare and Medicaid Innovation demonstration program of Value-Based Insurance Design (VBID), the investigators propose to…
- Trial name
- NCT05497999
- Testing
- Proactive Outreach, No Proactive Outreach
- Where
- 3 sites in United States
- Volunteers
- 19,113 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
COPD (Chronic Obstructive Pulmonary Disease)
Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD
Chronic obstructive pulmonary disease (COPD), one of the leading causes of death in the US, disproportionately affects low socioeconomic communities.
- Trial name
- RISE (NCT05572632)
- Testing
- COPD Wellness, COPD Wellness Plus+, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 387 people
- Sponsor
- University of California, San Francisco
Chronic Obstructive Pulmonary Disease (COPD)
Lung Ultrasound With Acute Exacerbation and Stable COPD
This cross-sectional study aims to compare lung ultrasound findings, functional capacity, and dyspnea among patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), patients with stable COPD, and…
- Trial name
- NCT07757126
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Obstructive Pulmonary Disease, Respiratory Failure
Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.
- Conditions
- Chronic Obstructive Pulmonary Disease, Respiratory Failure, Neuromuscular Diseases, Ventilatory Failure
- Trial name
- CRF-QoL (NCT04236726)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Chronic Obstructive Pulmonary Disease (COPD), Diaphragm Dysfunction
Effect of Inspiratory Muscle Training on Diaphragm Function in COPD Patients
This study investigates the effect of threshold inspiratory muscle training on diaphragm thickness and diaphragm excursion, measured using ultrasonography, in patients with stable chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT07539974
- Testing
- Threshold Inspiratory Muscle Training, Philips Respironics Threshold IMT device
- Volunteers
- 15 people
- Sponsor
- Universitas Padjadjaran
Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
Assessing the Occupation Burden in COPD
To assess the population burden of occupational exposures in the prevalence and progression of chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00006513
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
COPD
Placebo Controlled Evaluation of Sedation and Physiological Response to Intranasal Dexmedetomidine in Severe COPD
A variety of medications have been used to treat the anxiety, discomfort, and fear associated with continuous and sudden episodic breathlessness in patients with advanced respiratory disease.
- Trial name
- NCT02773797
- Testing
- IN-DEX 1.0 mcg/kg, intranasal saline, IN-DEX 1.5 mcg/kg, intranasal saline
- Where
- United States
- Sponsor
- Dayton VA Medical Center
Chronic Obstructive Pulmonary Disease (COPD)
A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to measure the safety and tolerability of TD 4208, an investigational drug being developed to treat people with moderate to very severe COPD, compared to tiotropium.
- Trial name
- NCT02518139
- Testing
- TD-4208, Tiotropium
- Where
- United States
- Volunteers
- 1,060 people
- Sponsor
- Mylan Inc.
COVID-19, Virus Diseases
Bacillus Calmette-guérin Vaccination to Prevent COVID-19
Based on findings of the interim analysis of the ACTIVATE study showing 53% decrease of the incidence of all new infections with BCG vaccination, a new trial is designed aiming to validate if BCG can protect against COVID-19…
- Conditions
- COVID-19, Virus Diseases, Corona Virus Infection, Coronary Heart Disease
- Trial name
- ACTIVATEII (NCT04414267)
- Testing
- BCG vaccine
- Where
- 15 sites in Greece
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Hellenic Institute for the Study of Sepsis
Chronic Obstructive Pulmonary Disease
A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD)
This is an open-label, Phase 3, long-term safety extension study including participants of previous lunsekimig clinical trials with inadequately controlled chronic obstructive pulmonary disease (COPD ) characterized by an…
- Trial name
- COLOSSUS (NCT07793409)
- Testing
- Lunsekimig
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 1,508 people
- Sponsor
- Sanofi
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