Clinical trials: Chronic Obstruct Airways Disease
Chronic Obstructive Pulmonary Disease
Balance Training in Patients With Chronic Obstructive Pulmonary Disease (COPD)
A growing body of evidence suggests that individuals with chronic lung disease have important deficits in balance control that may be associated with an increased risk of falls.
- Trial name
- NCT01424098
- Testing
- Balance training program
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Roger Goldstein
COPD, Smoking Cessation
Transtheoretical Model Based Nursing Interventions on Smoking Cessation in Patients With COPD
Background: The aim of this study is to evaluate the efficiency of nursing intervention based on smoking cessation transtheoretical model in patients with COPD who smoke Method: Experimental design was used in the study.
- Conditions
- COPD, Smoking Cessation, Home Visit
- Trial name
- NCT04313738
- Testing
- Assigned Interventions
- Volunteers
- 80 people
- Sponsor
- Dokuz Eylul University
Pulmonary Disease, Chronic Obstructive
A Dangerous Triad in Ageing and in Chronic Obstructive Pulmonary Disease (COPD) - Reduced Muscle Mass, Impaired Muscle Function and Malnutrition
The investigators have taken part in the development of simple muscle function tests and studied physical training and energy turnover in patients with chronic obstructive pulmonary disease, COPD.
- Trial name
- NCT01179178
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Göteborg University
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of Twice Daily 60mg AZD9668 in COPD for 12 Weeks in Patients on Background Budesonide/Formoterol
The primary objective is to evaluate the efficacy of AZD9668 compared with placebo in symptomatic COPD patients by assessing the effects on lung function and symptoms of COPD
- Trial name
- NCT01023516
- Testing
- AZD9668
- Where
- 66 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 615 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease (COPD)
Changes in Cardiac Function in COPD Patients After Administration of Budesonide/Formoterol (Symbicort®) Versus Placebo
To investigate whether Budesonide/Formoterol (Symbicort ®) therapy can improve heart function at rest by decreasing lung hyperinflation in patients with COPD (Chronic Obstructive Pulmonary Disease).
- Trial name
- AZCO (NCT01760304)
- Testing
- Budesonide / Formoterol
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease
Disturbed Blood Flow Induces Endothelial Dysfunction in Severe Chronic Obstructive Pulmonary Disease
The aim of the study is to determine if increased retrograde shear would further deteriorate the already impaired vascular function in severe COPD patients.
- Trial name
- NCT03004352
- Testing
- retrograde flow, oxygen
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Pulmonary Disease, Chronic Obstructive
Study of Relationship Between Changes in Inflammation, Lung Function, Symptoms and Medication Use in COPD Patients
The intention with the study is to have a better understanding of what happens to COPD patients' symptoms, lung function and markers of inflammation over 12 weeks.
- Trial name
- CORAL (NCT04168216)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Study to Investigate Daily Symptom Variability, Symptom Effects on Morning Activities of Chronic Obstructive Disease
The primary objective of this non-interventional study is to evaluate daily symptom variability in COPD patients. The secondary objectives are; to evaluate effects of COPD symptoms on the morning activities of patients, to…
- Trial name
- NCT01110564
- Where
- 19 sites in Turkey (Türkiye)
- Volunteers
- 515 people
- Sponsor
- AstraZeneca
Cancer, Chronic Obstructive Pulmonary Disease (COPD
Detection of Electrodermal Activity in Pain 2
The goal of this study is to investigate the association between self-reported pain and electrodermal activity and to create an algorithm that detects pain and provides timely alarms for rising pain levels in patients with…
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease (COPD, Pain
- Trial name
- DEEP 2 (NCT06677593)
- Where
- Denmark
- Volunteers
- 37 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
COPD, Sympathetic Nervous System Diseases
Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease
The project will be pursued in our respiratory, autonomic nervous system physiology laboratory (Respiratory, autonomic nervous system physiology laboratory, Department of Pneumology and Intensive Care Medicine, RWTH Aachen…
- Conditions
- COPD, Sympathetic Nervous System Diseases, Catecholamine; Overproduction
- Trial name
- SNAP-COPD (NCT04849806)
- Testing
- Assessments of the sympathetic nerve activity axis, OSA severity, Determination of PH and right HF severity
- Where
- Germany
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Chronic Obstructive Pulmonary Disease, Depression
Investigating the Impact of Mode of Administration on Item Response
The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Rheumatoid Arthritis
- Trial name
- NCT00783991
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- Stony Brook University
Chronic Obstructive Pulmonary Disease
Effects of Tiotropium/Olodaterol on Cardio-pulmonary Exercise Capacity in Patients With Hyperinflated Chronic Obstructive Pulmonary Disease [ACHIEVE]
[Background] Hyperinflation caused by increased airflow limitation and emphysema change commonly accompanies dyspnea, which leads to inactivity, reducing exercise capacity, and deconditioning.
- Trial name
- NCT04994574
- Testing
- tiotropium/olodaterol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Yonsei University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
High-Intensity vs Low-Intensity NPPV in Patients With an AECOPD: The HAPPEN Trial
To determine whether high-intensity NPPV, compared with low-intensity NPPV, could reduce the need for endotracheal intubation during hospitalization in patients with an AECOPD and hypercapnia.
- Trial name
- NCT02985918
- Testing
- High-intensity NPPV, Low-intensity NPPV
- Where
- 31 sites in China
- Volunteers
- 300 people
- Sponsor
- Beijing Chao Yang Hospital
COPD Exacerbation Acute
A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease, that causes obstructed airflow from the lungs that causes persistent obstructive airflow limitation.
- Trial name
- NCT05400369
- Testing
- Sitafloxacin, Moxifloxacin Hydrochloride
- Where
- 18 sites in China
- Volunteers
- 140 people
- Sponsor
- Daiichi Sankyo
Acute Decompensated Heart Failure, COPD Exacerbation
Use of ΔIVC for Early Diagnosis of AHF in AECOPD
Acute Heart failure (AHF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis.
- Trial name
- NCT05327374
- Testing
- calculation of the inferior vena cava collapsibility index
- Where
- 3 sites in Tunisia
- Volunteers
- 401 people
- Sponsor
- University of Monastir
COPD (Chronic Obstructive Pulmonary Disease), Quality of Life
Chronic Obstructive Pulmonary Disease, Quality of Life, COPD Assessment Test, Nepal, Dyspnea, Spirometry
Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. The study "Quality of life among people living with Chronic Obstructive Pulmonary Disease- visiting spirometry…
- Trial name
- NCT07261813
- Testing
- Evaluation of Quality of life in COPD patients
- Volunteers
- 71 people
- Sponsor
- Institute of medicine, Maharagjung medical campus
Chronic Obstructive Pulmonary Disease
The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV
The purpose of this study is to determine whether different types of breathing therapies in patients with COPD III-IV decrease dyspnea and increase activity.
- Trial name
- NCT01478646
- Testing
- conventional breathing therapy, reflectory breathing therapy
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Schön Klinik Berchtesgadener Land
COPD, Oxygen Therapy
Closed-loop System for Oxygen Delivery and Exercise in Chronic Obstructive Pulmonary Disease
The purpose of this study is to investigate the benefit of Closed-loop System for Oxygen Delivery (FreeO2) as compared with fixed oxygen flow during endurance shuttle walking test in patients with Chronic obstructive pulmonary…
- Conditions
- COPD, Oxygen Therapy, Hypercapnia
- Trial name
- FreeO2-rehab (NCT01575327)
- Testing
- Automated settings on the oxygen delivery device, Manual settings with FreeO2 system in collection mode
- Where
- 3 sites in France
- Volunteers
- 15 people
- Sponsor
- AGIR à Dom
Chronic Obstructive Pulmonary Disease
Enabling Independent Living by Expanding Access to Home-Based Pulmonary Rehabilitation
The purpose of this study is to test an existing home-based pulmonary rehab program with the addition of video chat and a capability of a Spanish version.
- Trial name
- NCT04479969
- Testing
- Video Chat
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
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