Clinical trials: Chronic Obstruct Airways Disease
Asthma, Chronic Obstructive Pulmonary Disease
ANASA (Patients' Satisfaction With Pulmonary Diseases' Treatment)
The aim of the study is to compare patients' satisfaction from the use of three different inhalation devices by using the FSI-10 questionnaire
- Trial name
- ANASA (NCT01475045)
- Where
- 2 sites in Greece
- Volunteers
- 1,160 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Chronic Obstructive Pulmonary Disease
Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease
The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe and 2) Is treatment effective in improving the health of patients with human Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT01559051
- Testing
- Lipoaspiration with Local anesthesia
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Chronic Obstructive Pulmonary Disease
Home-based in Chronic Obstructive Pulmonary Disease
Pulmonary rehabilitation consists of a multidisciplinary program of care for patients with chronic respiratory disease, which currently encompasses numerous features and physical training methods aimed at maintaining stability…
- Trial name
- HBCOPD (NCT01554072)
- Testing
- Home based pulmonary rehabilitation with exercise
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Pulmonary Disease, Chronic Obstructive
Effect of Macrolide Antibiotics on Airway Inflammation in People With Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease. Azithromycin, an antibiotic, may be beneficial at reducing the symptoms and severity of the disease.
- Trial name
- NCT00549445
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Alabama at Birmingham
COPD Chronic Obstructive Pulmonary Disease
Digital Follow-up Program for People with Chronic Obstructive Pulmonary Disease in Primary Healthcare
Chronic Obstructive Pulmonary Disease (COPD), characterized by non-reversible airflow obstruction, contributes to high mortality and morbidity rates worldwide, including Norway.
- Trial name
- NCT06401512
- Testing
- Guided self-determination (GSD) follow-up approach by primary care nurses.
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Western Norway University of Applied Sciences
Chronic Obstructive Lung Disease (COLD)
ANTEAB: a Study of Early Antibiotherapy in the ICU Management of Acute Exacerbations of COPD
Intensive Care Unit (ICU) admission for acute exacerbation of chronic obstructive lung disease (COLD) is a major cause of morbidity and mortality in such patients. Although bacterial of mortality in such patients.
- Trial name
- NCT00190437
- Testing
- Amoxicillin-clavulanic
- Where
- 2 sites in France
- Volunteers
- 520 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Lung Disease, Respiratory Ilness
InvEstigating oeStrogen Signalling and the Effect upoN the exTracelluar Matrix In pAtients With Obstructive Lung Disease
This study aims to understand the role of oestrogen in patients with asthma and Chronic Obstructive Pulmonary Disorder (COPD). Therefore, what is the effect of oestrogen in these participants compared to controls (those without…
- Conditions
- Chronic Obstructive Lung Disease, Respiratory Ilness, Estrogen Deficiency, Asthma
- Trial name
- ESSENTIAL (NCT06713512)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Smokers, Chronic Obstructive Pulmonary Disease
Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)
Chronic Obstructive Pulmonary Disease (COPD), , secondary to smoking, is a major public health issue with very high direct and indirect costs.
- Trial name
- ICONIC (NCT04252781)
- Testing
- Exhaustive exploration
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COPD
Effects of Long Term Macrolide Antibiotic Therapy in Patients With COPD
The purpose of this study is to determine whether long term treatment with oral erythromycin is effective in the treatment of subjects with Chronic Obstructive Pulmonary Disease (COPD) by reducing the number of exacerbations and…
- Trial name
- NCT00147667
- Testing
- Erythromycin
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Royal Free and University College Medical School
Pulmonary Disease, Chronic Obstructive
Safety And Efficacy Of UK-432,097 In Chronic Obstructive Pulmonary Disease.
Safety and efficacy (measured by spirometry) of UK-432,097 administration will be tested in patients with chronic obstructive pulmonary disease.
- Trial name
- NCT00430300
- Testing
- UK-432,097
- Where
- 22 sites in Australia, Canada and 3 more
- Volunteers
- 87 people
- Sponsor
- Pfizer
Pulmonary Disease, Chronic Obstructive
Dose Escalating Study of CCI15106 Inhalation Capsules in Healthy Subjects and Moderate Chronic Obstructive Pulmonary Disease (COPD) Patients
This study will be the first administration of CCI15106 capsules for inhalation to humans. The primary objective of the study is to investigate the safety and tolerability of single and repeat escalating doses of CCI15106 in…
- Trial name
- NCT03243760
- Testing
- CCI15106 7.5 mg capsule
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pneumonia, Acute Exacerbation of Chronic Obstructive Airways Disease
Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections
The purpose of this study is to investigate weather or not the use of a procalcitonin(PCT)-based treatment in the daily clinical work could lower the consumption of antibiotics in patients with lower respiratory tract infections.
- Trial name
- NCT02171338
- Testing
- PCT-level, Antibiotic treatment based on PCT-level
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Holbaek Sygehus
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study
Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study.
- Trial name
- NCT02557958
- Testing
- Azithromycin
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Chronic Obstructive Pulmonary Disease: COPD
Swiss studY for the Treatment of COPD Patients With the Free combiNation of indacatERol and GlYcopyrroniumbromide.
The study purpose is to evaluate the effect of QAB149 NVA237 vs. QAB149 on static lung hyperinflation.
- Trial name
- SYNERGY (NCT01699685)
- Testing
- QAB149, NVA237
- Where
- 11 sites in Switzerland
- Volunteers
- 79 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD), Airway Clearance
Oscillating Positive Expiratory Pressure Therapy Versus Autogenic Drainage in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a long-term lung condition that causes breathing difficulty, cough, and sputum production.
- Trial name
- OPEP-AD-COPD (NCT07402850)
- Testing
- Oscillating Positive Expiratory Pressure Therapy, Autogenic Drainage
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Adnan Hashim
Pulmonary Disease, Chronic Obstructive
Training of Inhalation Technique in Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Patients - a Pilot Study
Inhalation drugs are essential in the treatment of COPD, in controlling symptoms and preventing exacerbations. The aim of this pilot study is to collect data necessary for the planning of future efficacy trials.
- Trial name
- NCT03691324
- Testing
- Inhalation technique training and discharge service
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University College
COPD
Assessment of Severity and Prognosis in Elderly Patients With COPD and Complex Chronic Comorbidities
Cigarette smoking, the major risk factor for Chronic Obstructive Pulmonary Disease (COPD), causes systemic effects, such as systemic cellular and humoral inflammation, that could substantially contribute to the development of…
- Trial name
- NCT01893918
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Chronic Obstructive Pulmonary Disease
Predict&Prevent: Use of a Personalised Early Warning Decision Support System to Predict and Prevent Acute Exacerbations of COPD
COPD is a common complex disease with debilitating breathlessness; mortality and reduced quality of life, accelerated by frequent lung attacks (exacerbations).
- Trial name
- NCT04136418
- Testing
- COPDPredict mobile App, Usual care
- Where
- United Kingdom
- Volunteers
- 384 people
- Sponsor
- University of Birmingham
COPD
Assessing Exercise Capacity After PulseHaler™ Treatment in GOLD II-IV COPD Patients
Prospective, sham controlled, interventional study to evaluate the extent to which PulseHaler improves the functional status of Chronic Obstructive Lung Disease (GOLD) II-IV Chronic obstructive pulmonary disease (COPD) patients.
- Trial name
- NCT04236076
- Testing
- PulseHaler
- Volunteers
- 104 people
- Sponsor
- Respinova LTD
Chronic Obstructive Pulmonary Disease
Endoscopic Long Volume Reduction by Endobronchial Valves in Belgium
This a single center non-randomised non-sham controlled intervention study evaluating the effectiveness and safety of endoscopic lung volume reduction by endobronchial valves
- Trial name
- BEVA (NCT03264768)
- Testing
- endobronchial valves, physical activity tele coaching, Lung volume reduction surgery (LVRS)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- KU Leuven
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