Clinical trials: Chronic Obstruct Airways Disease
Chronic Obstructive Pulmonary Disease, Heart Failure
PATient Navigator to rEduce Readmissions
Staying out of the hospital is valued by patients and their caregivers. Their interests converge with those of hospitals now that high 30-day readmission rates for some conditions place hospitals at risk for financial penalties…
- Conditions
- Chronic Obstructive Pulmonary Disease, Heart Failure, Sickle Cell Disease, Myocardial Infarction
- Trial name
- PArTNER (NCT02114515)
- Testing
- Hospital usual care, Navigator intervention, Peer-led telephone support line
- Where
- United States
- Volunteers
- 1,029 people
- Sponsor
- University of Illinois Chicago
Copd, Smoking
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco.
- Conditions
- Copd, Smoking, Tobacco Use
- Trial name
- Pre-COPD Pilot (NCT04722835)
- Testing
- Bronchoscopy with Bronchoalveolar Lavage (BAL)
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Obstructive Pulmonary Disease, Asthma
Respiratory Registry for Lung Health: a Prospective, Observational Study on Adult Patients With Asthma or COPD
The database will contain a wide range of demographic, clinical, radiological, laboratory, functional, microbiological, treatment, and clinical outcomes data on adults with chronic obstructive pulmonary disease (COPD) and asthma…
- Trial name
- NCT05826613
- Where
- 4 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Chronic Obstructive Pulmonary Disease, COPD
Interleukin 6-guided Antibiotic Prescriptions in AECOPD Inpatients
In this multicenter, prospective, randomized controlled study, we aimed to figure out, compared with the global chronic obstructive pulmonary disease initiative (GOLD) guideline -guided antibiotic therapy, whether Interleukin 6…
- Trial name
- NCT06612476
- Testing
- Interleukin 6-guided antibiotic therapy, GOLD-guided antibiotic therapy
- Volunteers
- 440 people
- Sponsor
- Ningbo No. 1 Hospital
COPD
Bioequivalence Study of Tiotropium 18 μg Inhalation Powder, Hard Capsule With Spiriva®Handihaler® 18 μg Inhalation Powder, Hard Capsule in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Bioequivalence Study of Tiotropium Bromide Inhalation Powder 18 μg
- Trial name
- ARBORUS (NCT05986591)
- Testing
- Test Product - Tiotropium Bromide Inhalation Powder 18 mcg, Spiriva Handihaler (Tiotropium Bromide) 18 mcg
- Where
- 33 sites in United States, India
- Volunteers
- 335 people
- Sponsor
- Xiromed LLC
Pulmonary Disease, Chronic Obstructive
Effect of Spiriva® on Health-related Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients Who Stopped Smoking During Treatment.
Post marketing Surveillance to gain insights into the effects of therapy with Spiriva® (tiotropium bromide) on health-related quality of life in COPD patients who stopped smoking during treatment and to obtain safety data…
- Trial name
- NCT02172547
- Testing
- Spiriva
- Volunteers
- 10,821 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients
The investigators' aim is to study the effect of cycling off criteria during pressure support ventilation in COPD patients at two levels of PEEP and PSV.
- Trial name
- NCT00141440
- Testing
- mechanical ventilation
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Policlinico Hospital
Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation
6-minute Stepper Test and Pulmonary Rehabilitation in Patients With Severe to Very Severe Chronicle Obstructive Pulmonary Disease
Chronicle obstructive pulmonary disease is a worldwide cause of mortality and morbidity. This systemic disease progressively leads to dyspnea, muscle wasting and exercise capacity impairment.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation, 6-minute Stepper Test
- Trial name
- 6STaR-2 (NCT04004689)
- Testing
- 2 times : 6-minute stepper test with a rest of 20min between each test.
- Where
- 4 sites in France
- Volunteers
- 80 people
- Sponsor
- ADIR Association
Chronic Obstructive Pulmonary Disease
Respiratory Muscle Function, Diaphragm Thickness and Health Related Physical Fitness Parameters in Individuals
In the literature, studies evaluating respiratory muscle function, diaphragm thickness and health-related physical fitness parameters together are insufficient in individuals with chronic obstructive pulmonary disease.
- Trial name
- NCT04995510
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Abant Izzet Baysal University
Chronic Obstructive Pulmonary Disease (COPD)
Noninvasive Ventilation on Chronic Obstructive Pulmonary Disease (COPD) Patient Functionality
On the following tests, there would be a greater increase in the functionality of COPD patients who underwent combined therapy than in those who only exercised: a set of activities of daily living (ADLs), the six-minute walk test…
- Trial name
- kmarrara (NCT01464736)
- Testing
- physical training
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- Universidade Federal de Sao Carlos
Asthma-COPD Overlap Syndrome
A Non-interventional Study to Investigate the Current Situation of Asthma-COPD Overlap Syndrome in Patients Over Age 40 With Persistent Airflow Limitation in China
To investigate the distributions of the patients with ACOS, asthma and COPD over age 40 with chronic airflow limitation in China.
- Trial name
- NCT02600221
- Where
- 13 sites in China
- Volunteers
- 2,016 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Inspiratory Muscle Training and Respiratory Electromyographic Activity in COPD
Intended to treat disorders of the respiratory muscles can use the device Threshold IMT ® through an inspiratory muscle training (IMT) that allows training of the inspiratory muscles, the chief of these being the diaphragm which…
- Trial name
- NCT02014155
- Testing
- Inspiratory Muscle Training, Pulmonary Rehabilitation
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Santa Cruz do Sul
Chronic Obstructive Pulmonary Disease (COPD)
2-arm Parallel Group Study of Fixed Combination of CHF 5993 vs Ultibro® in COPD Patients
The aim of the present study is to evaluate the superiority of the fixed triple therapy with BDP/FF/GB at a daily dose of 400/24/50 mcg respectively with that of Ultibro® Breezhaler® (DPI), fixed combination of indacaterol 85 mcg…
- Trial name
- TRIBUTE (NCT02579850)
- Testing
- Central spirometry, COPD assessment test, Local laboratory Assessments
- Where
- Italy
- Volunteers
- 1,532 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Chronic Obstructive Pulmonary Disease
Clinical Trial of Efficacy and Safety of Rengalin in the Treatment of Cough in Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to obtain additional data on efficacy and safety of Rengalin in the treatment of cough in patients with stable obstructive pulmonary disease
- Trial name
- NCT03159091
- Testing
- Rengalin
- Where
- 18 sites in Russia
- Volunteers
- 238 people
- Sponsor
- Materia Medica Holding
Chronic Obstructive Pulmonary Disease
Characteristics of Intestinal Microbiome in the Progression of Early COPD
This study is aiming at explore the characteristics of intestinal microbiome during the early progression of COPD, the correlation between the changes of intestinal microbiome and the severity and risk of acute exacerbation of…
- Trial name
- NCT04876833
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Effect of the Combination of Umeclidinium (UMEC) and Vilanterol (VI) on Exercise Endurance Time (EET) in Participants With Chronic Obstructive Pulmonary Disease (COPD)
This is a multicenter, randomized, double-blind, placebo-controlled, 2-period, complete block design cross-over study. The purpose of this study is to evaluate the effect of UMEC/VI 62.5/25 microgram (mcg) on EET as measured by…
- Trial name
- NCT02275052
- Testing
- UMEC/VI DPI, Albuterol/salbutamol MDI
- Where
- 10 sites in United States
- Volunteers
- 198 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Effects of Singing in Chronic Obstructive Pulmonary Disease
The purpose of this study is to investigate the effects of the practice of singing for a long period of time on pulmonary function data, quality of life, and dyspnea sensation of patients with COPD in stable clinical conditions.
- Trial name
- NCT00500526
- Testing
- Singing practice, Singing classes, Hand craft classes
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- University of Sao Paulo
Chronic Obstructive Pulmonary Disease, Balance Impairment
The Relationship Between Pain, Balance and Gait in People With Chronic Obstructive Pulmonary Disease
The balance, gait and pain in Chronic Obstructive Pulmonary Disease (COPD) study will aim to investigate the link between balance and gait impairment, and high rates of pain in people with COPD.
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance Impairment, Gait Impairment, Pain
- Trial name
- NCT04202991
- Testing
- Exposure - pain
- Where
- 2 sites in United Kingdom
- Volunteers
- 43 people
- Sponsor
- Teesside University
Lung Cancer, Precancerous Condition
Studying Genes in Blood and Lung Fluid Samples From Patients With Chronic Obstructive Pulmonary Disease With or Without a Previous Diagnosis of Lung Cancer or With Asthma Treated With Budesonide and Formoterol
RATIONALE: Studying the genes expressed in samples of blood and lung fluid in the laboratory from patients receiving budesonide and formoterol may help doctors learn more about the effect of budesonide and formoterol on gene…
- Trial name
- NCT00569712
- Testing
- budesonide/formoterol fumarate dihydrate inhalation aerosol, DNA methylation analysis, comparative genomic hybridization
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- British Columbia Cancer Agency
Chronic Obstructive Pulmonary Disease
Efficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28-Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this Phase III study is to evaluate the long-term safety and tolerability of two fixed-dose combinations of inhaled aclidinium bromide/formoterol fumarate, aclidinium bromide, formoterol fumarate and placebo in…
- Trial name
- NCT01572792
- Testing
- Aclidinium bromide/formoterol Fixed-Dose Combination (FDC), Aclidinium bromide, Formoterol Fumarate
- Where
- 208 sites in United States, Australia and 2 more
- Volunteers
- 921 people
- Sponsor
- AstraZeneca
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