Clinical trials: Chronic Obstructive Pulmonary
Cough, COPD
Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease
This study pretends to evaluate the potential use of Hyfe Cough Tracker (Hyfe) to screen for, diagnose, and support the clinical management of patients with respiratory diseases, while enriching a dataset of disease-specific…
- Conditions
- Cough, COPD, GERD, Asthma
- Trial name
- NCT05042063
- Testing
- Hyfe Cough Tracker, Hyfe Air
- Where
- Spain
- Volunteers
- 616 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive
Transforming Psychotherapy for Chronically Ill Patients
The primary objective of this research is to pilot test a brief mental heath treatment specifically tailored to meet the needs of chronically ill patients with anxiety and/or depression.
- Conditions
- Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive, Depression, Anxiety
- Trial name
- NCT00520429
- Testing
- ACCES - Adjusting to Chronic Conditions with Education and Support
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Obstructive Pulmonary Disease
Systemic Endothelial Abnormalities in COPD
The purpose of this project is to validate the peripheral arterial pressure waveform measurements technique of RAAP (radial artery applanation tonometry), in patients with moderate and severe COPD (Chronic Obstructive Pulmonary…
- Trial name
- NCT00555529
- Testing
- radial artery applanation tonometry (RAAP)
- Where
- 2 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
COPD
HDAC Activity in Peripheral Skeletal Muscle in COPD
We wish to study the effect of Chronic Obstructive Pulmonary Disease on the activity of the nuclear transcription pathway in peripheral skeletal muscle to determine whether altered activity of this pathway may be responsible for…
- Trial name
- NCT00180752
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease (COPD), Mental Imagery
Motor Imagery in Chronic Obstructive Pulmonary Disease
The purpose of this study was to compare the motor imagery ability of individuals with Chronic Obstructive Pulmonary Disease (COPD) with those without COPD.
- Trial name
- NCT07171957
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sinus; Empyema, Maxillary (Chronic)
The Osteogenic Potential of Human Maxillary Sinus Shneiderian Membrane
The objectives of this study are : 1. to test the the osteogenic potential of human maxillary sinus schneiderian membrane (hMSSM). 2.
- Trial name
- HMSSM (NCT02676921)
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BERBERI ANTOINE
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib
Nemiralisib is a potent anti-inflammatory agent for the treatment of chronic obstructive pulmonary disease (COPD) and other inflammatory lung diseases.
- Trial name
- NCT03398421
- Testing
- Nemiralisib, Itraconazole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cardiovascular Disease (CVD), Chronic Obstructive Pulmonary Disease (COPD)
Towards Personalized Nutrition With SCAPIS2-HOME
The Swedish CardioPulmonary bioImage Study (SCAPIS) is a nationwide, open-access, population-based cohort in Sweden designed to study cardiovascular disease and chronic obstructive pulmonary disease.
- Trial name
- NCT06992921
- Testing
- Dietary intervention
- Where
- 2 sites in Sweden
- Volunteers
- 1,641 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Healthy Participants
A Study to Assess the Pharmacokinetics of AZD6793 When Administered Alone and in Combination With Itraconazole in Healthy Participants.
The study will evaluate the pharmacokinetics (PK) of AZD6793 when administered alone and in combination with itraconazole in healthy adult participants.
- Trial name
- NCT06494644
- Testing
- AZD6793, Itraconazole, AZD6793+ Itraconazole
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Heart Failure, Chronic Obstructive Pulmonary Disease
TeleHomecaRe InterVention Evaluation Study
The goal of this study is to evaluate the overall impact of Telehomecare on COPD and HF patients and system level outcomes using a comparison group of patients that did not participate in the program (for up to 18 months).
- Trial name
- THRIVE (NCT03212001)
- Where
- Canada
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pulmonary Disease, Chronic Obstructive
Erythrocytes Membrane Stability in COPD Patients in Long-Term Home Oxygen Therapy
Chronic Obstructive Pulmonary Disease (COPD) patients in Long-Term Home Oxygen Therapy (LTOT) have a reduction in airflow that is not totally reversible.
- Trial name
- NCT02732444
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Chronic Obstructive Pulmonary Disease, Asthma
Lung Deposition of Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium Bromide Administered Via pMDI in Healthy, Asthmatic and COPD Patients
The purpose of this study is to investigate the lung deposition and distribution pattern of Beclometasone dipropionate/Formoterol Fumarate/Glycopyrronium Bromide using a Gamma-scintigraphic technique after inhalation of a single…
- Trial name
- NCT02975843
- Testing
- Beclometasone dipropionate/Formoterol Fumarate/Glycopyrronium
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Pulmonary Disease, Chronic Obstructive
Assessment of Lung Function After Single Inhalations of a Bronchodilator From 2 Configurations a Dry Powder Inhaler.
GSK573719 is a high-affinity specific muscarinic receptor (mAChR) antagonist which is being developed for the treatment of chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01521390
- Testing
- GSK573719 62.5 mcg (one strip), GSK573719 62.5 mcg(two strips), GSK573719 125 mcg (one strip)
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease, Asthma
Lung Deposition of TRIMBOW® pMDI in Healthy Volunteers, Asthmatic and COPD Patients
The purpose of this study is to investigate the lung deposition and distribution pattern of TRIMBOW using a Gamma-scintigraphic technique after inhalation of a single dose of 99mTc radiolabelled TRIMBOW administered via pMDI in…
- Trial name
- STORM (NCT03795350)
- Testing
- Beclometasone dipropionate Formoterol Fumarate Glycopyrronium Bromide
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Chronic Obstructive Pulmonary Disease
The Differences of Muscle Activity Between Patients With COPD and Healthy Adults
The purpose of this study attempts to investigate the differences and relationships of respiratory parameters, muscle activity, and dyspnea during ADL between patients with COPD and age-matched healthy participants.
- Trial name
- NCT04146948
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Chronic Obstructive Pulmonary Disease
Pennsylvania Study Of Chronic Obstructive Pulmonary Exacerbations
The overall purpose of PA-SCOPE is to determine why black and rural residents of Pennsylvania might be at higher risk for deadly, debilitating, and costly hospitalizations for chronic obstructive pulmonary disease (COPD)- and…
- Trial name
- PA-SCOPE (NCT00774176)
- Where
- 3 sites in United States
- Volunteers
- 1,066 people, healthy volunteers welcome
- Sponsor
- Temple University
COPD, HIV/AIDS
Determining Bacterial Communities in the Lungs of HIV-infected Individuals With COPD in Uganda.
Research question Is there any association between altered lung bacterial communities and HIV-associated Chronic Obstructive Pulmonary Disease (COPD)? Rationale Sub-Saharan Africa has experienced dramatic increases in COPD…
- Trial name
- LMB (NCT04070248)
- Testing
- No intervention
- Where
- Uganda
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Makerere University
Cystic Fibrosis, Chronic Obstructive Pulmonary Disease
A Phase 1 Study to Characterize the Effect of GS-5737 Enhancement of Mucociliary Clearance (MCC) in Healthy Subjects
This is a randomized, double-blind, cross-over, vehicle-controlled study to determine whether GS-5737 in 2.8% saline accelerates mucociliary clearance (MCC) in healthy subjects, compared to vehicle of 2.8% saline alone.
- Trial name
- NCT01793649
- Testing
- GS-5737
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
COPD
Phase 1/Phase 2a Study of AERO-007 Inhalation Solution, a Nebulized LABA/LAMA Combination for Maintenance Treatment of COPD
This is a phase 1/phase 2a, single dose, crossover study conducted in two parts. Part 1: Phase 1, open-label, 4-period crossover study in 8 healthy subjects to determine the optimal dose of AERO-001 and AERO-002, the active…
- Trial name
- NCT06841640
- Testing
- AERO-001, AERO-002, AERO-007
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AeroRx Therapeutics Inc.
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