Clinical trials: Chronic Obstructive Pulmonary
COPD (Chronic Obstructive Pulmonary Disease), Caregiver
Validation of the French Version of the QASCI in Caregivers of Patients With COPD
This study aims to validate the French version of the QASCI questionnaire, initially written and validated in Portuguese language by Hipolito et al., to assess caregiving burden in chronic obstructive pulmonary disease (COPD).
- Trial name
- VALQASCI (NCT06652204)
- Testing
- questionnaire
- Where
- 2 sites in France
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
COPD, Health Literacy
Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in COPD
Health literacy is important for controlling disease progression and living a healthy life with illness. High health literacy is associated with higher cognitive performance and lower health-related quality of life.
- Conditions
- COPD, Health Literacy, Health-Related Behavior
- Trial name
- NCT06497816
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Gingivitis; Chronic, Oxidative Stress
Efficacy of Green and White Tea Extract Mouthwashes in the Management of Plaque-induced Gingivitis: A Clinical and Biochemical Study
Background and objective: Tea is the second most consumed drink in the world after water. Gingivitis is among the most common infectious diseases.
- Conditions
- Gingivitis; Chronic, Oxidative Stress, Inflammation
- Trial name
- NCT05861206
- Testing
- GT-MW group (5% Green tea), WT-MW group (5% White tea),EO-MW group (Listerine mouthrinse), CHX-MW group (0.12% CHX, as a positive control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Yağmur Saraç Gül
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib
Nemiralisib is a potent anti-inflammatory agent for the treatment of chronic obstructive pulmonary disease (COPD) and other inflammatory lung diseases.
- Trial name
- NCT03398421
- Testing
- Nemiralisib, Itraconazole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers
Smoking damages the airway epithelium. The major mechanism by which this is done is by molecules called free radicals. Our body attempts to deal with these damaging molecules in two ways.
- Trial name
- NCT00565214
- Testing
- Group 1, Group 2
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pulmonary Function
Effects of Particulate Matter on the Pulmonary Function and Acute Exacerbation of COPD and Asthma
Particulate matter(PM) exposure has been shown to increase the morbidity and mobility of a variety of respiratory diseases, including COPD and asthma.
- Trial name
- NCT03193879
- Where
- China
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Asthma, Pulmonary Disease, Chronic Obstructive
Teaching Inhaler Use With the INCA Device in a Community Pharmacy Setting
The purpose of this trial is to discover whether providing feedback to patients from a device that records when and how well a patient uses a Seretide Diskus inhaler will lead to: Improved compliance with prescribed inhaler use…
- Trial name
- NCT02203266
- Testing
- Feedback, Education
- Where
- Ireland
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Beaumont Hospital
Copd
The Effect Of Blood Flow Restrıcted Resistive And Aerobic Exercises in Chronic Obstructive Pulmonary Patients
Patients with chronic obstructive pulmonary disease (COPD) classified by a pulmonologist in accordance with the GOLD criteria will be randomly divided into 2 groups.
- Trial name
- COPD (NCT04521959)
- Testing
- Blood flow restricted and normal aerobic exercise and resistance exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medipol University
Chronic Obstructive Pulmonary Disease (COPD)
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1)
A prospective multi-center study to define the sensitivity and specificity of CAPTURE for identifying previously undiagnosed patients with clinically significant COPD in a broad range of primary care settings.
- Trial name
- CAPTURE (NCT03581227)
- Testing
- CAPTURE Tool
- Where
- 8 sites in United States
- Volunteers
- 4,679 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Health, Health Adult Subjects
DBM-1152A Inhalation Solution in Chinese Healthy Subjects
This is a Phase Ia, single-center, randomized, double-blind, placebo-controlled, single ascending dose (SAD) study. The primary purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of DBM-1152A…
- Trial name
- NCT07447141
- Testing
- DBM-1152A Inhalation Solution
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Joincare Pharmaceutical Group Industry Co., Ltd
Chronic Obstructive Pulmonary Disease
An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease
This study is investigating the possible mechanisms of action of an inhaled treatment (Seretide), currently used worldwide in millions of patients with COPD (Chronic Obstructive Pulmonary Disease) and how it improves the symptoms…
- Trial name
- IMAS (NCT00974805)
- Testing
- Seretide 500 Accuhaler
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Bronchopulmonary Dysplasia, Preterm Birth
Bronchopulmonary Dysplasia: From Neonatal Chronic Lung Disease to Early Onset Adult COPD
The investigators will apply xenon-129 (129Xe) and non-contrast enhanced magnetic resonance imaging (MRI) acquisition and analysis methods in 50 subjects aged between 20 and 29 years born pre-term (with and without a diagnosis of…
- Trial name
- NCT02723513
- Testing
- Hyperpolarized Xenon-129
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Cancer, Chronic Obstructive Pulmonary Disease
Does Continuous Vital Sign Monitoring Increase Investigations and Interventions in Complication-free Patients?
This aim of this study is to investigate whether active alerts during CVSM result in an increased number of diagnostic tests and treatments in complication free patients, hypothesizing that more interventions are performed in the…
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease, Surgery-Complications
- Trial name
- WARD-OT (NCT06361862)
- Testing
- Active alarms from WARD software
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COPD, Microbial Colonization
Partially Hydrolyzed Guar Gum (PHGG) for Amelioration of Chronic Obstructive Pulmonary Disease (COPD)
Some components of the diet could promote the growth of certain bacterial strains present in the intestine, which are closely associated with benefits for host health.
- Conditions
- COPD, Microbial Colonization, Respiratory Tract Disease
- Trial name
- NCT05126654
- Testing
- Partially Hydrolyzed Guar Gum (PHGG)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
COPD
Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)
This study will determine the functional status of the nasal immune environment with LAIV exposure in COPD persons with frequent exacerbations (defined as individuals with two or more episodes of worsening in COPD symptoms…
- Trial name
- NCT04901455
- Testing
- LAIV
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Obstructive Pulmonary Disease
Vowel Segmentation for Classification of Chronic Obstructive Pulmonary Disease Using Machine Learning
This work aims to evaluate whether the segmentation of vowel recordings collected from patients diagnosed with COPD and healthy control groups can increase the classification precision of machine learning techniques.
- Trial name
- NCT06160674
- Testing
- COPD
- Where
- Sweden
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Cholecystitis, Chronic
Outcomes of Three Ports Versus Four Ports Laparoscopic Cholecystectomy, Sohag General Surgery Department Experience
To compare the outcomes of three ports and four ports Laparoscopic Cholecystectomy
- Trial name
- NCT06264115
- Testing
- Laparoscopic Cholecystectomy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Healthy, Pulmonary Disease, Chronic Obstructive
Relative Bioavailability of Olodaterol and Fluconazole
This clinical trial is intended to investigate a possible effect of the CYP 2C9 inhibitor fluconazole on the bioavailability of olodaterol
- Trial name
- NCT01153724
- Testing
- BI 1744, Fluconazole
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hematologic Neoplasms
Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
Background: People with blood cancers often receive blood or bone marrow transplants. But even with these treatments, the risk of relapse is high.
- Trial name
- NCT05327023
- Testing
- donor lymphocyte infusion, Cyclophosphamide, Busulfan
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Pulmonary Disease, Chronic Obstructive
Succinate Salt Version of GSK961081 for Healthy Volunteers
Salt Bridging study for GSK961081
- Trial name
- NCT00550225
- Testing
- GSK961081
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
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