Clinical trials: Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
Vibration Training in Chronic Obstructive Pulmonary Disease (COPD)-Patients During a Three-week Rehabilitation
The aim of this study is to investigate the change of physical activity in COPD-patients performing a whole body vibration training additional to a standard three-week rehabilitation program in comparison to patients performing…
- Trial name
- NCT01380652
- Testing
- whole body vibration training
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Schön Klinik Berchtesgadener Land
COPD, Pulmonary Rehabilitation
Effects of Respiratory Rehabilitation by Gender in COPD Patients
Without calling into question the effectiveness of pulmonary rehabilitation in women, the difference in outcome by gender was not established due to insufficient evidence .
- Trial name
- REHABGENRE (NCT04297514)
- Where
- France
- Volunteers
- 504 people
- Sponsor
- University Hospital, Brest
COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation Chronic Obstructive Pulmonary Disease
Muscle Oxygenation in Patients With COPD Exacerbation
Chronic obstructive pulmonary disease (COPD) is often complicated by acute exacerbations, which lead to functional impairments, increased dyspnea, and a rapid decline in lung function.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation Chronic Obstructive Pulmonary Disease, Muscle Oxygenation
- Trial name
- NCT07801547
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Chronic Obstructive Pulmonary Disease, Anxiety
"Consultation Liaison and Integrated Care for COPD Patients With Psychiatric Co-Morbidity"
Chronic obstructive pulmonary disease (COPD) stands out among chronic diseases with its high and rising prevalence and mortality, poor quality of life, high re-hospitalization rates and societal burden of care.
- Conditions
- Chronic Obstructive Pulmonary Disease, Anxiety, Depression
- Trial name
- COPD_HSRG (NCT01644916)
- Testing
- Integrated care, Usual control
- Where
- Singapore
- Volunteers
- 295 people
- Sponsor
- National University of Singapore
Small Airway Disease, Asthma
Small Airways Disease (SAD) in Severe Asthma as a Novel Endpoint and Distinct Target for Biological Therapy.
Severe asthma is now widely accepted to be a heterogeneous syndrome consisting of multiple phenotypes identified by specific biomarkers and targeted by tailored biological therapies.
- Trial name
- SASAB (NCT05792592)
- Testing
- IOS (Impulse Oscillometry)
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Obstructive Pulmonary Disease
Transdiaphragmatic Pressure and Neural Respiratory Drive Measured During Inspiratory Muscle Training in COPD
Inspiratory muscle training（IMT）was an rehabilitation therapy for stable patients with chronic obstructive pulmonary disease(COPD).
- Trial name
- NCT03017300
- Testing
- Threshold IMT®, PFLEX®
- Volunteers
- 12 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma, COPD
Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease
The aim of the project is to study pathogenetic mechanisms in severe asthma and compare those mechanisms in chronic obstructive pulmonary disease (COPD) in order to test the hypothesis that severe asthma and COPD develop into…
- Trial name
- BIOAIR (NCT00555607)
- Testing
- prednisolone
- Where
- Sweden
- Volunteers
- 233 people
- Sponsor
- Karolinska Institutet
Coronary Heart Disease, Stroke
The Copenhagen City Heart Study
The Copenhagen City Heart Study is an ongoing cardiovascular population study initiated in 1976 which has examined approximately 25,000 individuals from the general population.
- Conditions
- Coronary Heart Disease, Stroke, Heart Failure, Cancer
- Trial name
- CCHS (NCT02993172)
- Volunteers
- 23,891 people
- Sponsor
- Bispebjerg Hospital
COPD
Safety, Tolerability, and Clinical Activity of ASM-024 Administered to Patients With GOLD 2 or GOLD 3 Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to evaluate the safety, tolerability, and clinical activity of ASM-024 administered as a dry powder for inhalation formulation to patients with GOLD 2 or GOLD 3 COPD.
- Trial name
- NCT01855230
- Testing
- ASM-024
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Asmacure Ltée
Chronic Obstructive Pulmonary Disease
Patient-Ventilator Interactions in Chronic Obstructive Pulmonary Diseases (COPD) Under Non-Invasive Ventilation
Non-invasive ventilation (NIV) in severe hypercapnic Chronic Obstructive Pulmonary Diseases (COPD) may be associated - during sleep - with recurrent episodes of patient ventilatory asynchrony, which in turn may affect quality of…
- Trial name
- NCT01180439
- Testing
- Adjustment of ventilator settings (device)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Ligue Pulmonaire Genevoise
Chronic Bronchitis
Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis
This is a prospective, randomized, parallel group, double-blind, sham-controlled, multicenter clinical trial following patients to 2 years.
- Trial name
- RheSolve (NCT04677465)
- Testing
- RheOx Bronchial Rheoplasty
- Where
- 37 sites in United States, Austria and 3 more
- Volunteers
- 270 people
- Sponsor
- Gala Therapeutics, Inc.
COPD
Comparative Effects of IMT Vs EMT Along With AIT in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is the 3rd leading cause of mortality and 7th leading cause of ill-health worldwide.
- Trial name
- NCT06308302
- Testing
- Group A (Inspiratory Muscles Training + Aerobic Interval Training), Group B (Expiratory Muscles Training +Aerobic Interval Training)
- Where
- Pakistan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Riphah International University
COPD (Chronic Obstructive Pulmonary Disease)
Vitamin C's Antioxidant Effects and COPD Prognosis
This multicenter, randomized, double-blind, placebo-controlled clinical trial aims to evaluate the efficacy of Vitamin C supplementation in improving the prognosis of patients with Chronic Obstructive Pulmonary Disease (COPD)…
- Trial name
- NCT06664957
- Testing
- Vitamin C (Ascorbic Acid)
- Volunteers
- 650 people
- Sponsor
- Ningbo No. 1 Hospital
Pulmonary Disease, Chronic Obstructive
Effect of Tiotropium on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Study to investigate whether tiotropium therapy can increase duration of steady-state exercise by decreasing dynamic and static lung hyperinflation in COPD patients.
- Trial name
- NCT02172300
- Testing
- Tiotropium inhalation capsules
- Volunteers
- 198 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Evaluation of Efficacy on Exercise Tolerance of Symbicort (Budesonide/Formoterol) Compared to Placebo and Oxis in Patients With Severe COPD
The purpose of this study is to investigate the effect on exercise tolerance, lung function and symptoms after treatment with Symbicort, Oxis or placebo in patients with severe chronic obstructive pulmonary disease.
- Trial name
- CODEX (NCT00489853)
- Testing
- budesonide/formoterol Turbuhaler 320/9µg, formoterol Turbuhaler 9µg
- Where
- 9 sites in Germany, Switzerland
- Volunteers
- 137 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD
This is an open-label Phase II study assessing the PD of dexpramipexole 150 mg twice daily (BID) in participants with eosinophilic COPD.
- Trial name
- SUSPIRE-1 (NCT06533553)
- Testing
- Dexpramipexole Dihydrochloride
- Where
- 23 sites in United States
- Volunteers
- 30 people
- Sponsor
- Areteia Therapeutics
COPD
Impact of Morning Symptoms in Clinical Control of Chronic Obstructive Pulmonary Disease (COPD)
Observational study to know the Impact of morning symptoms in clinical control of COPD patients. 1200 patients will be included by General practitioners (GPs) and pneumologists.
- Trial name
- IMPAEPOC (NCT01266395)
- Where
- 52 sites in Spain
- Volunteers
- 1,268 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Short Chain Fatty Acid Metabolism in COPD
The short chain fatty acid (SCFA) metabolism has not been studied in subjects suffering from COPD. The purpose of this study is to compare the SCFA metabolism in COPD patients to healthy matched controls.
- Trial name
- SCFA (NCT03327181)
- Testing
- short chain fatty acid tracers
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
COPD
A Clinical Trial to Evaluate the Efficacy and Safety of HRS-9821 Inhalation Suspension in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
The study is being conducted to evaluate the efficacy and safety of HRS-9821 for patients with COPD, and to explore the reasonable dosage of HRS-9821 for patients with COPD.
- Trial name
- NCT07640451
- Testing
- HRS-9821 Inhalation Suspension
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
COPD
Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients
The objectives of this study are to assess the effect of salbutamol in comparison with ipratropium bromide on the geometry of central and peripheral airways and to correlate spirometric indices with the Computational Fluid…
- Trial name
- NCT00911651
- Testing
- Salbutamol, ipratropium bromide
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- University Hospital, Antwerp
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