Clinical trials: Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
The Difference in the Biological Characteristic Characteristics of the Heart and Lung Meridians
The association between viscera and the body surface remains obscure, but a better understanding of it will maximize its diagnostic and therapeutic values in clinical practice.
- Trial name
- NCT05690217
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Pulmonary Disease, Chronic Obstructive
Evaluation of the Effect of Roflumilast in Hyperinflated COPD Patients Using Functional Respiratory Imaging
In this study the efficacy of Roflumilast in addition to LAMA/LABA therapy will be assessed using Functional Respiratory Imaging.
- Trial name
- NCT02451540
- Testing
- HRCT scan, Roflumilast
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- FLUIDDA nv
Pulmonary Disease, Chronic Obstructive
A 3 Way Cross-over Study Evaluating the Effects of ADOAIR Twice Daily Plus Tiotropium Bromide Once Daily Compared With the Individual Treatments of Japanese Subjects
The purpose of this study is to evaluate the effects on lung function of a combination of ADOAIR 50/250mcg twice daily plus tiotropium bromide 18mcg once daily compared with the individual treatments (tiotropium bromide 18mcg…
- Trial name
- SCO116572 (NCT01751113)
- Testing
- fluticasone propionate/salmeterol, tiotropium bromide, fluticasone propionate/salmeterol plus tiotropium bromide
- Where
- 3 sites in Japan
- Volunteers
- 53 people
- Sponsor
- GlaxoSmithKline
Sarcopenia, COPD
Sarcopenia in Chronic Lung Diseases
Inclusion criteria A)Outpatients with COPD (chronic obstructive pulmonary disease) or ILD (interstitial lung disease) from department of Chest medicine in Taichung Veterans General Hospital, judged by the doctor that they do not…
- Conditions
- Sarcopenia, COPD, Asthma, ILD
- Trial name
- NCT06280443
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Taichung Veterans General Hospital
Hypertension, Pulmonary, Pulmonary Disease, Chronic Obstructive
Single Dose Study in Patients With Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension.
This study is to demonstrate the safety, tolerability, pharmakokinetic and pharmacodynamic effect of a single oral dose of BAY63-2521 in patients with pulmonary hypertension due to chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00640315
- Testing
- Riociguat (Adempas, BAY63-2521) 1.0 mg, Riociguat (Adempas, BAY63-2521) 2.5 mg
- Where
- 7 sites in Germany
- Volunteers
- 23 people
- Sponsor
- Bayer
COPD, Diabetes
Effectiveness of Physical Exercise of Patients With Chronic Non-communicable Disease
According to the Pan American Health Organization (PAHO), chronic, non-communicable diseases (NCDs) are the main cause of death and disability in the world.
- Conditions
- COPD, Diabetes, Physical Inactivity, Frailty
- Trial name
- NCT06476015
- Testing
- Therapeutic exercise
- Where
- Colombia
- Volunteers
- 300 people
- Sponsor
- Fundacion Universitaria Maria Cano
Chronic Obstructive Pulmonary Disease
Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC Trial
A randomised controlled trial to test the hypothesis that inhaled therapies for chronic obstructive pulmonary disease (COPD) have differential effects on the upper airway microbiome.
- Trial name
- MUSIC (NCT02972476)
- Testing
- Budesonide & formoterol fumarate and Aclidinium bromide, Fluticasone 500 & salmeterol and Aclidinium bromide, Fluticasone 250 & salmeterol and Aclidinium bromide
- Where
- 6 sites in United Kingdom
- Volunteers
- 158 people
- Sponsor
- University of Dundee
Pulmonary Disease, Chronic Obstructive
Phase 2 Study of the Safety and Efficacy of UK-500,001 in Adult Patients With COPD
This initial proof of concept, phase II study aims to assess the safety and efficacy of UK-500,001 for the chronic maintenance treatment of adults with Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT00263874
- Testing
- UK-500,001
- Where
- 28 sites in Argentina, Australia and 8 more
- Volunteers
- 324 people
- Sponsor
- Pfizer
Pulmonary Disease, Chronic Obstructive
Evaluation of Lung Function and Symptoms in Patients Diagnosed With Chronic Obstructive Pulmonary Disease (COPD) on Long-Acting Bronchodilator Monotherapy
A multicenter study to evaluate lung function and symptoms in subjects with COPD who have been on regular use of only one long-acting bronchodilator.
- Trial name
- LABD (NCT00791518)
- Testing
- No intervention
- Where
- 57 sites in United States
- Volunteers
- 1,084 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this interventional, randomized, double-blind, monocentric, cross-over study is to quantify the possible deleterious effect on the cardiac autonomic nervous system control of two long-acting anticholinergic…
- Trial name
- LAB-Card (NCT02872090)
- Testing
- Indacaterol, Glycopyrronium, Tiotropium
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Lung Diseases, Obstructive, Blood Eosinophil Count
Corticosteroid Reduction in COPD
This study explores whether patients hospitalized with chronic obstructive pulmonary disease (COPD) exacerbation may have fewer days with prednisolone and with the same treatment effect by controlling the treatment by daily…
- Conditions
- Lung Diseases, Obstructive, Blood Eosinophil Count, Glucocorticoids, COPD
- Trial name
- Cortico-cop (NCT02857842)
- Testing
- Prednisolone
- Where
- 4 sites in Denmark
- Volunteers
- 318 people
- Sponsor
- Chronic Obstructive Pulmonary Disease Trial Network, Denmark
Chronic Obstructive Pulmonary Disease
Mindfulness to Mitigate the Effect of Anxiety-depression-fear in Chronic Obstructive Pulmonary Disease (COPD)
People with COPD have a greater risk for symptoms of depression, anxiety, and fear of breathlessness. Those emotions are independently associated with lower physical activity, poorer quality of life, and higher hospitalization…
- Trial name
- NCT03385317
- Testing
- Mindfulness
- Where
- United States
- Sponsor
- Mayo Clinic
Esophageal Perforation
A 75 Year Old With Dyspnea a Case Report.Observational Study
Clinical Case report Of spontaneous esophageal perforation in a 75 year old man. He prsented with breathlessness and on investigation found to have esophageal perforation
- Trial name
- NCT00422760
- Volunteers
- 1 people
- Sponsor
- Stanley Medical College
Pulmonary Disease, Chronic Obstructive
Study to Compare the Addition of Umeclidinium Bromide (UMEC) to Fluticasone Furoate (FF)/Vilanterol (VI), With Placebo Plus FF/VI in Subjects With Chronic Obstructive Pulmonary Disease (COPD) -Study 2
After screening, subjects will enter a 4 week open-label run-in period with fluticasone furoate (FF)/vilanterol (VI) 100/25 mcg administered once daily via dry powder inhaler (DPI).
- Trial name
- NCT02119286
- Testing
- FF, VI, UMEC
- Where
- 57 sites in United States, Czechia and 2 more
- Volunteers
- 620 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea
Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome
The purpose of this study is to determine if Bipap should assume a standard-of-care role in the management of overlap syndrome.
- Conditions
- Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overlap Syndrome
- Trial name
- OS (NCT01427673)
- Testing
- Bipap procedure
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- United States Air Force
COPD Exacerbation
Low-dose CT for Diagnosis of Pneumonia in COPD Exacerbations and Comparison of the Inflammatory Profile.
Hypothesis: There is an underdiagnosis of pneumonia in COPD (Chronic Obstructive Pulmonary Disease) exacerbations which could be demonstrated by performing low-dose chest CT.
- Trial name
- NCT02264483
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation
Effectiveness of a Home-based Pulmonary Rehabilitation Program in COPD Patients
The study aims to develop and test the effectiveness of a new home-based pulmonary rehabilitation program comprising two distinct phases, the first in which an 8-week respiratory rehabilitation program is carried out the second…
- Trial name
- Rehab2life (NCT05315505)
- Testing
- Maintenance programme, Usual Care
- Where
- Portugal
- Volunteers
- 160 people
- Sponsor
- Unidade Local de Saúde de Matosinhos, EPE
Chronic Obstructive Lung Disease
EFFECT OF COMBINED VIRTUAL REALITY-GUIDED BREATHING AND AEROBIC TRAINING ON VENTILATORY FUNCTION IN PATIENTS WITH COPD
This Single-blind, randomized controlled trial will evaluate the effects of 12 weeks of combined VR-guided diaphragmatic breathing (Flowborne) and VR-aerobic cycling (Kinneta) compared with conventional pulmonary rehabilitation…
- Trial name
- VR-COPD (NCT07885995)
- Testing
- VR-Based Pulmonary Rehabilitation Group, Conventional Pulmonary Rehabilitation Group
- Volunteers
- 60 people
- Sponsor
- Cairo University
COPD
Early Palliative Care for Patients With Severe and Very Severe COPD: a Randomised Study
Chronic obstructive pulmonary disease (COPD) is a common and, despite existing treatment options, progressive lung disease. Patients with COPD often have only limited access to palliative care.
- Trial name
- NCT02223780
- Testing
- early palliative care
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- University Hospital, Geneva
Copd, Chronic Respiratory Disease
Quality-of-Life Management for COPD Patients
The investigators aim to investigate the effects of a telemonitoring and chatbot-based application of "Living well with COPD" (CAir) on health-related quality-of-life in patients with COPD.
- Trial name
- CAir (NCT04373070)
- Testing
- CAir
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University of Zurich
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