Clinical trials: Chronic Obstructive Pulmonary Disease (COPD)
COPD, Chronic Obstructive Pulmonary Disease
Observational Study of the Wellinks Solution Impact on Quality of Life and Clinical Outcomes in Patients With COPD
The clinical objectives of this study are to determine whether utilization of the Wellinks COPD Solution can improve quality of life for patients with COPD, can reduce healthcare resource utilization over time, and can improve…
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Severe, Chronic Obstructive Pulmonary Disease Moderate
- Trial name
- ASPIRE (NCT05259280)
- Testing
- Wellinks
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- Convexity Scientific Inc
COPD
Zofin to Treat Chronic Obstructive Pulmonary Disease (COPD)
A Phase I/II Randomized, Double Blinded, Placebo Trial to Evaluate the Safety and Potential Efficacy of Intravenous Infusion (IV) of Zofin for the Treatment of Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT05643729
- Testing
- Zofin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ZEO ScientifiX, Inc.
COPD
Causes of Appetite Loss in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The project looks at causes of appetite loss in patients with COPD. It is know that active systemic inflammation can lead to appetite loss and COPD is classified as a disease lead by inflammation.
- Trial name
- NCT04754256
- Testing
- Council of Nutrition Appetite Questionnaire - test for applicability in Danish COPD patients
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Jens Rikardt Andersen
COPD, Emphysema, Asthma COPD Overlap, Emphysema
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (>15 pack years) with COPD, Emphysema, and…
- Trial name
- NCT03263130
- Testing
- As above: diagnosis: COPD, Emphysema, Asthma-COPD Overlap
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gelb, Arthur F., M.D.
COPD
COPD Pal Phase 1: A Self-management App in COPD
Chronic Obstructive Pulmonary Disease (COPD) is a widespread condition which causes a poorer health status, reduced exercise, and lung function impairment.
- Trial name
- NCT04142957
- Testing
- COPD Pal
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Hywel Dda Health Board
COPD
Palliative Care Health Literacy Education and QOL Compared to Usual Care
The goal of this pilot randomized controlled trial is to compare health literacy (HL) and quality of life (QOL) among older adults with chronic obstructive pulmonary disease (COPD) who completed a series of standardized…
- Trial name
- PACED (NCT06089499)
- Testing
- Get Palliative Care: four educational learning module videos
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Asthma, COPD
Can we Reduce Hospital Attendance Without Compromising Care by the Use of Telephone Consultation
Consultation time in busy respiratory clinics is inevitably limited and attendance is often disruptive to patients' lives; involves time, expense, travel, and waiting; and can have effects upon occupation.
- Conditions
- Asthma, COPD, Sleep Apnea Syndromes, Interstitial Lung Diseases
- Trial name
- NCT00129701
- Testing
- Telephone consultation
- Where
- United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Imperial College London
COPD, Cough
A Clinical Validation Study to Evaluate the Diagnostic Accuracy of a Cough-based Auxiliary Diagnosis Algorithm for COPD
Cough is one of the most common symptoms in COPD patients, and its different characteristics in amplitude, frequency and waveform can be analyzed by intelligent algorithms for the auxiliary diagnosis of COPD.
- Conditions
- COPD, Cough, Algorithm
- Trial name
- NCT06082791
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
COPD
Measurement of Smoking-Induced Neutrophil Activation
Neutrophil involvement in the development of COPD by smokers is well recognised. However not all smokers develop overt lung disease.
- Trial name
- NCT00159354
- Testing
- predisolone
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Imperial College London
COPD, Interstitial Lung Disease
Anxiety Management in Breathlessness.
The goal of this mixed methods study is to learn about cranial electrotherapy stimulation (CES) using Alpha-Stim AID in anxiety related to breathlessness in advanced lung diseases.
- Trial name
- NCT06066658
- Testing
- cranial electrotherapy stimulation (Alpha-Stim AID)
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Leicester
COPD, COPD Exacerbation Acute
Clopidogrel for the Prevention of Exacerbations in Severe COPD
Chronic Obstructive Pulmonary Disease (COPD) is a debilitating respiratory disorder characterized by gradual and progressive airflow limitation.
- Trial name
- CLOPEX (NCT06021990)
- Testing
- Clopidogrel Bisulfate 75Mg Tab
- Where
- 2 sites in Pakistan
- Volunteers
- 162 people
- Sponsor
- Lady Reading Hospital, Pakistan
COPD
Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose Combination in pMDI Form in Stable Chronic Obstructive Pulmonary Disease (COPD) Patients
The goal of this clinical trial is to compare the acute bronchodilator effect of pMDI formed Ipratropium / Levosalbutamol 20 mcg / 50 mcg fixed dose combination or pMDI formed Salbutamol 100 mcg Inhaler and Ipratropium 20 mcg…
- Trial name
- NCT06040424
- Testing
- Ipratropium / Levosalbutamol Fixed Dose Combination, Ipratropium + Levosalbutamol Free Dose Combination
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Impact of Switching COPD Patients From Inhaler Devices to the Omron C28P Nebuliser.
The cornerstone of COPD therapy is based on the use of inhalation drugs. The correct use of devices is crucial; a suboptimal use technique is the cause of a possible clinical deterioration with a consequent increase in…
- Trial name
- OMRON (NCT06061679)
- Testing
- Omron C28P nebuliser
- Volunteers
- 99 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
COPD, Self-management Behaviors
Comprehensive Self-management Support for COPD Patients
The study team will adapt and expand an effective model of asthma self-management support for patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- SAMBA COPD (NCT04533412)
- Testing
- Self-management barrier support, Basic COPD Education
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
COPD
Long-term Observational Study of the Safety of Roflumilast
This is a retrospective cohort study comparing COPD patients aged 40 years and older with new exposure to roflumilast with up to 5 unexposed (ie, not roflumilast-exposed) COPD controls matched by propensity score (PS), age, sex…
- Trial name
- NCT03381573
- Testing
- Roflumilast
- Where
- 4 sites in United States, Germany and 2 more
- Volunteers
- 135,856 people
- Sponsor
- AstraZeneca
Malnutrition, Cancer
Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients
This study aims to compare nutritional outcomes in terms of percentage of weight gain between a new planted-based high-energy ONS and a standard high-energy ONS with animal protein (cow's mil protein) in patients at malnutrition…
- Conditions
- Malnutrition, Cancer, Inflammatory Bowel Diseases, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06055543
- Testing
- Fortimel
- Where
- 6 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Danone Specialized Nutrition
COPD, Bronchiolitis
A Feasibility RCT of Aerobika Verses ACBT in People With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a common preventable and treatable respiratory condition. Its main symptoms include, breathlessness, cough and frequent chest infections.
- Trial name
- TIPTOP (NCT05548036)
- Testing
- OPEP
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Carwyn Bridges
Chronic Obstructive Pulmonary Disease (COPD)
COPD Treatment by Transplantation of Autologous Bronchial Basal Cells
Chronic obstructive pulmonary disease (COPD) is a group of disease characterized by obstructed airflow. Usually, the lung structure is gradually impaired along with the progression of the disease.
- Trial name
- NCT05594303
- Testing
- Autologuos transplantation of bronchial basal cells
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma, Allergic Rhinitis
Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China.
To investigate the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya.
- Conditions
- Asthma, Allergic Rhinitis, Chronic Obstructive Pulmonary Disease(COPD), Atopic Dermatitis
- Trial name
- NCT05330637
- Testing
- Climate and environment in Sanya
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine