Clinical trials: Chronic Pain, Widespread
Chronic Widespread Pain, Fibromyalgia
Efficacy and Safety of IGN-ES001 in Chronic Widespread Pain With or Without Fibromyalgia
This is a randomized, double-blind, placebo-controlled exploratory trial to investigate efficacy and safety of food supplement IGN-ES001 in patients with chronic widespread pain (CWP) with or without fibromyalgia (FM).
- Trial name
- NCT03058224
- Testing
- IGN-ES001, Parol 500 mg Tablets (acetaminophen)
- Where
- 23 sites in Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- IgNova GmbH
Anxiety Disorder, Chronic Myeloproliferative Disorders
Music Therapy to Ease Pain and Emotional Distress in Patients With Hematologic Cancer Who Are Undergoing High-Dose Therapy and Stem Cell Transplantation
RATIONALE: Music therapy may be effective in relieving pain and emotional distress in patients who are undergoing cancer therapy.
- Conditions
- Anxiety Disorder, Chronic Myeloproliferative Disorders, Depression, Lymphoma
- Trial name
- NCT00014482
- Testing
- pain therapy, psychosocial assessment and care
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Widspread Chronic Pain, Fibromyalgia
The Effect of Vagus Nerve Stimulation on Pain and Functional Activities in Individuals With Chronic Widespread Pain
The goal of this clinical trial is to examine the effect of vagus nerve stimulation (VNS) on chronic, widespread pain in adults.
- Trial name
- NCT07080749
- Testing
- Vagal nerve stimulation through deep exhalation exercise, Vagal nerve stimulation through ear electrical stimulation, No intervention (observational study)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Georgia
Carpal Tunnel Syndrome, Chronic Pain
Local Injection of Ozone Versus Methylprednisolone Acetate in Carpal Tunnel Syndrome of Scleroderma Patients
Carpal tunnel syndrome is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent local ozone therapy could offer symptom improvement in scleroderma patients with Carpal tunnel syndrome
- Conditions
- Carpal Tunnel Syndrome, Chronic Pain, Scleroderma
- Trial name
- NCT03742466
- Testing
- Ozone, methylprednisolone acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy
Effects of Adding Vagal Neuromodulation to Manual Therapy in Women With Fibromyalgia
The aim of this study is to investigate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) added to manual therapy on pain, autonomic nervous system function, and illness perception in female patients…
- Conditions
- Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy, Chronic Widespread Pain, Autonomic Nervous System Dysfunction
- Trial name
- NCT07894588
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Manual Therapy Program, Diaphragmatic Breathing and Stretching Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hasan Kalyoncu University
Amplified Musculoskeletal Pain Syndrome (AMPS)
Efficacy and Safety of Nerivio for the Management of Amplified Musculoskeletal Pain Syndrome in Pediatric Patients
The goal of this trial is to learn how the Nerivio® device works to treat Amplified Musculoskeletal Pain Syndrome (AMPS) in children ages 8-18. Nerivio® is a wearable device that activates specific nerves in the upper arm.
- Trial name
- Nerivio (NCT07249931)
- Testing
- Nerivio(R) Device, Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Health
Arthritis, Fibromyalgia
Effectiveness of Therapeutic Exercise on the Gut Microbiome in Chronic Widespread Pain Patients.
This study aims to evaluate the effect of therapeutic exercise on the gut microbiome in chronic widespread pain patients. Our investigation purpose is to improve the quality of life of participants, reduce their disability and…
- Conditions
- Arthritis, Fibromyalgia, Arthritis Rheumatoid, Artrosis of the Knee
- Trial name
- MiBioPain (NCT05932433)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad Rey Juan Carlos
Pain, Chronic
Group intEgrative MINdfulness Over the Internet Using an Online Platform
This is a one-year study designed to improve upon the latest version of an education website for adult chronic pain patients called Our Whole Lives for Chronic Pain (OWL-CP).
- Trial name
- GEMINI (NCT04340739)
- Testing
- online patient education teach mindfulness based stress reduction
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Massachusetts, Worcester
Pain, Chronic, Widespread Chronic Pain
myoActivation® for Chronic Pain in a Marginalized Population
Marginalized populations are at increased risk of chronic pain, trauma and use of street drugs to manage this suffering, with the associated risk of overdoses.
- Trial name
- NCT04261959
- Testing
- myoActivation
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of British Columbia
Hyperthermia, Chronic Primary Pain
Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain
This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the…
- Conditions
- Hyperthermia, Chronic Primary Pain, Widespread Pain, Muscular Disease
- Trial name
- HYPPRI-1 (NCT07101978)
- Testing
- serial whole body hyperthermia
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Chronic Pain, Chronic Pain Syndrome
Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents
The goal of this clinical trial is to learn if adding Shiatsu therapy to standard treatment can improve quality of life in children and adolescents with chronic pain that is not caused by inflammation.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain and Comorbid Emotional Problems, Chronic Pain, Psychogenic
- Trial name
- ShiQoL (NCT06929598)
- Testing
- Shiatsu Therapy
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Tel Aviv University
Chronic Widespread Pain
Effects of Acupuncture on Pain and Quality of Life of People Affected With Chronic Widespread Pain.
Background: Chronic Widespread Pain (CWP) is a multidimensional disorder for which treatment as yet remains unsatisfactory. Acupuncture is one of the most sought therapeutic methods when it comes to alternative medicine, due to…
- Trial name
- NCT03081091
- Testing
- Acupuncture
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universitat de Girona
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Chronic Pain, Chronic Pain Syndrome
Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain
This study will evaluate a new form of non-invasive deep brain therapy for individuals with generalized chronic pain. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation…
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Widespread Chronic Pain
- Trial name
- DBT (NCT05674903)
- Testing
- Verum stimulation with Diadem prototype
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Chronic Pain, Widespread
A Multi-disciplinary Pain Intervention (MUD-PI) for Patients With Chronic Widespread Primary Pain
Patients who fulfilled inclusion criteria and consented to participate received either treatment as usual at the clinic, or were enrolled in a group-therapy based intervention, the multi-disciplinary pain intervention, led by a…
- Trial name
- MUD-PI (NCT03413501)
- Testing
- MUD-PI
- Volunteers
- 49 people
- Sponsor
- Oslo University Hospital
Chronic Pain, Widespread, Obesity
Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults
The goal of this observational study is to learn if surgical weight loss can improve chronic widespread pain in people living with higher BMI who self-identify as Hispanic/Latino ethnicity or non-Hispanic Black based on the…
- Conditions
- Chronic Pain, Widespread, Obesity, Bariatric Surgery Candidate
- Trial name
- NCT06795386
- Testing
- Bariatric Surgery
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- New York University
Chronic Myeloproliferative Disorders, Leukemia
Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases
RATIONALE: Listening to relaxing music during a bone marrow biopsy may be effective in reducing anxiety and pain. PURPOSE: This randomized clinical trial is studying how well music works in reducing anxiety and pain in adult…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00376922
- Testing
- music therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Chronic Widespread Pain
Enhancing Analgesia in Chronic Pain Through Exercise
Background: Current pain management strategies for pediatric patients are not integrating the analgesic potential of movement-based therapies.
- Conditions
- Pain, Chronic Widespread Pain, Fibromyalgia
- Trial name
- NCT04862871
- Testing
- Physical Activity - Pediatric Pain Rehabilitation Center
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Musculoskeletal Diseases or Conditions, Neurologic Disorder
Clinical Course of Patients Receiving Physiotherapy Services in Primary Health Care
Background: Physiotherapists (PTs) in primary health care manage patients with a large variation in medical diagnosis, age, functional status, disability and prognosis.
- Conditions
- Musculoskeletal Diseases or Conditions, Neurologic Disorder, Widespread Chronic Pain, Psychosomatic Disorder
- Trial name
- FYSIOPRIM (NCT03626389)
- Testing
- Physiotherapy
- Where
- 2 sites in Norway
- Volunteers
- 4,985 people
- Sponsor
- University of Oslo