Clinical trials: Chronic Pain, completed
Chronic Migraine or Episodic Migraine
Study to Evaluate the Efficacy and Safety of AMG 301 in Migraine Prevention
To evaluate the effect of AMG 301 compared to placebo on the change from the baseline period in monthly migraine days in subjects with migraine.
- Trial name
- NCT03238781
- Testing
- AMG 301
- Where
- 49 sites in United States, Austria and 6 more
- Volunteers
- 343 people
- Sponsor
- Amgen
Migraine
Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients
The purpose of this study was to evaluate the efficacy and safety of erenumab in patients with chronic migraine in Asian population.
- Trial name
- DRAGON (NCT03867201)
- Testing
- Erenumab
- Where
- 63 sites in China, India and 7 more
- Volunteers
- 557 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Non-Specific Neck Pain
Telerehabilitation Exercise Program for Individuals With Chronic Non-Specific Neck Pain
This study examined whether a 6-week telerehabilitation exercise program could reduce pain and improve daily functioning in people with chronic non-specific neck pain.
- Trial name
- NCT07188701
- Testing
- Telerehabilitation Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Gelisim University
Pain, Chronic, Breast Cancer
Optimizing Psychological Treatment for Pain After Breast Cancer: A Pilot Study
The present study is a pilot study that aims to evaluate the feasibility, validity, and preliminary efficacy of three psychological treatment components for pain after breast cancer, which will be evaluated in a larger trial…
- Trial name
- NCT04841928
- Testing
- Mindful attention, Decentering, Value-based action
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Aarhus
Chronic Low-back Pain, Disc Degeneration
Evaluation of Safety, Tolerability, and Efficacy of CordSTEM-DD in Patients With Chronic Low Back Pain
The purpose of this clinical study is to evaluate the safety, tolerability, and efficacy of CordSTEM-DD, an allogeneic umbilical cord-derived mesenchymal stem cell, as a cell-therapeutic drug in patients with chronic low back…
- Trial name
- NCT04530071
- Testing
- CordSTEM-DD (0.7 x 10^7 cells), CordSTEM-DD (2.1 x 10^7 cells)
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- CHABiotech CO., Ltd
Respiratory Depression
Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo.
The purpose of this study is to explore and compare VRH after administration of Belbuca, Oxycodone HCl and Placebo in recreational opioid users.
- Trial name
- NCT03996694
- Testing
- Belbuca 300 µg, Belbuca 600 µg, Belbuca 900 µg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- BioDelivery Sciences International
Chronic Pelvic Pain Syndrome, Pelvic Floor; Relaxation
Effects of Breathing Exercises in Women With Chronic Pelvic Pain
The primary cause of the complex interaction of chronic pelvic pain originates from the visceral organs in the pelvic cavity, and it has been observed that musculoskeletal dysfunctions (such as increased muscle activity in the…
- Conditions
- Chronic Pelvic Pain Syndrome, Pelvic Floor; Relaxation, Breathing Exercises, Women
- Trial name
- NCT05875545
- Testing
- Breathing Exercises, Pelvic Floor Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Saglik Bilimleri Universitesi
Pain
Pain Evaluation and Treatment
This study offers evaluation and treatment for patients with a spectrum of acute and chronic pain syndromes. The protocol is not designed to test new treatments; rather, patients will receive current standard of care treatments.
- Trial name
- NCT00362167
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Chronic Pain, Back Pain
Safety and Efficacy Study of the Evoke™ SCS System With Feedback vs. Conventional Stimulation
The purpose of this study is to evaluate the safety and efficacy of the Saluda Medical Evoke SCS System with feedback control to treat chronic pain of the trunk and/or limbs.
- Conditions
- Chronic Pain, Back Pain, Pain
- Trial name
- EVOKE (NCT02924129)
- Testing
- Evoke Spinal Cord Stimulator (SCS) System
- Where
- 16 sites in United States
- Volunteers
- 134 people
- Sponsor
- Saluda Medical Americas, Inc.
Metabolic Syndrome, Physical Activity
The Effectiveness of Dry Needling and Classic Physiotherapy Programs in The Patients Suffering From Chronic Low Back Pain Caused by Lumbar Disc Hernia
Aim: This study was planned for comparing physical activity levels, nutrition quality and quality of life of the individuals that are diagnosed with and without metabolic syndrome (MetS) and that live in the Turkish Republic of…
- Conditions
- Metabolic Syndrome, Physical Activity, Quality of Life
- Trial name
- NCT02865200
- Testing
- Dry Needling Application, Classic Physiotherapy Program
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Knee Arthritis, Knee Osteoarthritis
Gold Factor on Knee Joint Health and Function
The purpose of this clinical study was to determine whether gold nanoparticles (AuNP) supplement holds clinical value in improving joint health, function, and quality of life for arthritis patients.
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic, Knee Discomfort
- Trial name
- NCT05347602
- Testing
- Gold Factor (Gold Nanoparticles, AuNPs)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- 4Life Research, LLC
Non-specific Chronic Neck Pain
Effect of Kendall and Scapulothoracic Exercises in Treatment of Chronic Non-specific Neck Pain
The purpose of the clinical trial is to investigate the effect of the combined Kendall and scapulothoracic exercises program on mechanosensitivity of brachial plexus, cervical range of motion, neck functional ability, and…
- Trial name
- NCT06980337
- Testing
- Conventional treatment program, Scapulothoracic exercises, Kendall exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Critical Limb Ischemia
Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia
This study will compare the effectiveness of best available surgical treatment with best available endovascular treatment in adults with critical limb ischemia (CLI) who are eligible for both treatment options.
- Trial name
- BEST-CLI (NCT02060630)
- Testing
- Open surgical revascularization, Endovascular revascularization
- Where
- 161 sites in United States, Canada and 3 more
- Volunteers
- 1,843 people
- Sponsor
- Carelon Research
Chronic Pain, Pain, Chronic
Pain at Work Toolkit in Employees With Chronic Pain
This project will test the feasibility and acceptability of the Pain at Work (PAW) Toolkit which aims to help employees self-manage chronic or persistent pain at work.
- Trial name
- PAW (NCT05838677)
- Testing
- Pain at Work Toolkit, Active control
- Where
- United Kingdom
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Chronic Low Back Pain
Pain Neuroscience Education Delivered During Aerobic Exercise Versus Exercise Alone
Chronic musculoskeletal pain is a common health condition that reduces quality of life and increases disability. Pain neuroscience education (PNE) has shown positive effects on pain perception, beliefs, and function, especially…
- Trial name
- PNE-MOVE (NCT07152171)
- Testing
- Pain Neuroscience Education During Aerobic Exercise, Aerobic Exercise Alone
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Ankle Inversion Sprain, Chronic Instability of Joint
Effectiveness of Balance Training and Dynamic Neuromuscular Stabilization Training in Amateur Athletes with Chronic Ankle Instability
The goal of this clinical trial is to determine and compare the effects of balance and dynamic neuromuscular stabilization training on ankle function ability, functional instability severity, physical activity level, muscle…
- Conditions
- Ankle Inversion Sprain, Chronic Instability of Joint, Chronic Pain, Athlete Foot
- Trial name
- NCT06296537
- Testing
- Dynamic Neuromuscular Stabilization Training (DNS), Balance Training, Conventional Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Medipol University
Chronic Pain
Effectiveness of the Precision Spinal Cord Stimulator System at Sub-Perception Amplitude
To demonstrate sustained clinically significant pain relief in patients with chronic pain when using the Boston Scientific Precision Spinal Cord Stimulator (SCS) System at sub-perception amplitude
- Trial name
- WHISPER (NCT02314000)
- Testing
- Precision or Precision Spectra Spinal Cord Stimulator System
- Where
- 26 sites in United States
- Volunteers
- 229 people
- Sponsor
- Boston Scientific Corporation
PTSD, Chronic Pain
iACT for PTSD and Chronic Pain : a Development Pilot Series
The primary aim of this study is to investigate the effect of Internet-delivered Acceptance and commitment therapy for PTSD and comorbid chronic pain.
- Trial name
- NCT04306809
- Testing
- Internet-delivered ACT for PTSD and chronic pain
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Skane University Hospital
Neck Pain
Sensorimotor Exercises and Neurodevelopmental Yoga in Chronic Neck Pain
Neck pain is an important public health problem with a high lifetime prevalence and frequently occurring in all industrialized countries. Clinical practice guidelines for chronic neck pain recommend conservative management.
- Trial name
- NCT06236737
- Testing
- Sensorimotor Exercise, Yoga Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Musculoskeletal Diseases, Work-Related Condition
Individuals With Chronic Work-related Musculoskeletal Disease a Multidisciplinary Care Program
Rehabilitation for work-related musculoskeletal disorders involves physical, behavioral, psychological treatment and counseling on how to deal with pain and disability.
- Conditions
- Musculoskeletal Diseases, Work-Related Condition, Chronic Pain
- Trial name
- NCT05150730
- Testing
- Multi professional care
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Cidade de Sao Paulo
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