Clinical trials: Chronic Pain, completed
Chronic Pain
Genetic Determinants of Amitriptyline Efficiency for Pain Treatment
Low dose tricyclic antidepressant drugs are routinely administered co-analgesics in pain medicine. Amitriptyline is largely considered as a gold standard. Amitriptyline underlies cytochrome CYP2D6 and CYP2D19 metabolism.
- Trial name
- NCT02256943
- Testing
- Amitriptyline, Tolterodine
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Neurofibromatosis
Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic Pain
Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that can cause frequent and significant pain. This pain can have a severe impact on a person s quality of life.
- Trial name
- NCT01633008
- Testing
- ACT Workshop
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Low Back Pain
Pain Neuroscience Education and Gradual Exposure to Exercise in Factory Workers With Chronic Low Back Pain
This study aims to compare the effectiveness of a pain neuroscience education (PNE) based programe and gradual exposure to exercise versus pilates on disability levels associated with chronic low back pain in factory workers.
- Trial name
- NCT04191317
- Testing
- Pain Neuroscience Education and gradual exposure, Pilates and postural education
- Where
- Portugal
- Volunteers
- 37 people
- Sponsor
- Aveiro University
Chronic Pain, Disability Physical
Physical Therapy to Treat Chronic Pain in Survivors of Trauma
This study will assess the effects of physical therapy (PT) for individuals who are survivors of trauma (SOT) and have chronic pain.
- Trial name
- NCT03933189
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Vermont
Hand Joint Discomfort
Evaluation of Flexofytol® PLUS in Hand Joint Chronic Dyscomfort.
The purpose of this study is to evaluate the effect of curcuminoids and Boswellia serrata extracts combination (Flexofytol PLUS) in support to standard treatments during a 12-weeks period on hand pain on people with chronic hand…
- Trial name
- NCT05089318
- Testing
- Flexofytol PLUS
- Where
- 2 sites in Belgium
- Volunteers
- 239 people
- Sponsor
- Tilman S.A.
Chronic Back Pain, Depression
Improving Outcomes for Older Veterans With Chronic Back Pain and Depression
The overarching goal of this study is to develop and evaluate a telephone delivered behavioral change intervention for older Veterans with chronic low back pain (cLBP) and comorbid depression, and to ultimately assess its effect…
- Conditions
- Chronic Back Pain, Depression, Aging
- Trial name
- NCT03896035
- Testing
- Behavioral Intervention Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Pain, Chronic
Examining the Effects of Float-REST for Recovery in Individuals With Chronic Lower Back Pain
Researchers at the West Virginia University Rockefeller Neuroscience Institute are looking for volunteers to participate in a research study to evaluate what effects Float-REST (Restricted environmental Stimulation Technique) has…
- Trial name
- NCT05260918
- Testing
- Float-REST, Nappod
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- West Virginia University
Chronic Low Back Pain, Hip Ostearthritis
Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
Back pain is a huge problem for millions of Americans, including nearly 11 million Veterans. Our older Veterans suffer the most. Citizens spend billions of dollars, yet consistently get poor results.
- Conditions
- Chronic Low Back Pain, Hip Ostearthritis, Myofascial Pain Syndrome, Fibromyalgia
- Trial name
- NCT02697435
- Testing
- Patient-Centered Care, Imaging-Directed Care
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Neck Pain
Effects of Single Thoracic Manipulation and Special Massage Technique (RT Technique) on Chronic Mechanical Neck Pain
This study aims to compare the immediate effects of using a single thoracic manipulation combined with special massage technique (RT technique) and single thoracic manipulation alone on pain level at rest, cervical range of…
- Trial name
- NCT03187808
- Testing
- Single thoracic manipulation, Special massage technique (RT technique)
- Volunteers
- 30 people
- Sponsor
- Khon Kaen University
Chronic Pain Syndrome
Thermal Micro-cautery for Painful Knee Osteoarthritis
To trial a traditional pain management technique from Ayurveda in a modern way - the technique involves micro - cautery to painful areas in knee osteoarthritis for patients on a waiting list for knee replacement.
- Trial name
- TMC-PKO (NCT03460717)
- Testing
- Peripheral Nerve Field Stimulation by Thermal Micro-Cautery
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- The National Children's Hospital, Tallaght
Fibromyalgia (FM), Chronic Pain
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Symptom Severity, Sleep Quality, Central Sensitization, and Kinesiophobia in Fibromyalgia
Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and sensitivity to touch. Current treatments often provide only partial relief.
- Trial name
- NCT07173400
- Testing
- Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hatice Betigul Meral
Low Back Pain
Effectiveness and Safety of Atelocollagen in the Management of Chronic Non-specific Low Back Pain
The purpose of this study was to evaluate the effectiveness and safety of atelocollagen in the management of chronic low back pain with sarcopenia due to degenerative changes.
- Trial name
- NCT04933838
- Testing
- atelocollagen
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University
Chronic Pain
Investigate the Efficacy and Effectiveness of Aromatherapy for the Management of Chronic Pain
In recent decades, following an increased longevity in Hong Kong, there is a drastic increase in the prevalence chronic conditions, including chronic pain, seems to be the main reasons of suffering for many older adults.
- Trial name
- NCT03561844
- Testing
- aromatherapy
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT
Pilot RCT of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Ankle and Foot Pain
Injections of local anesthetics (freezing) and steroids are often performed around injured nerves in individuals with nerve injury-related pain.
- Trial name
- PREPLANS (NCT02680548)
- Testing
- 0.9% saline, 0.25% bupivacaine hydrochloride injectable suspension USP, 4mg/cc methylprednisolone acetate injectable suspension USP
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University Health Network, Toronto
Scapular Dyskinesia
Correlation Between Scapular Dyskinesia and Thoracic Kyphosis
This study will be conducted to investigate: 1. the correlation between scapular dyskinesis and thoracic kyphosis in patients with chronic nonspecific neck pain 2.
- Trial name
- NCT07806955
- Testing
- Lateral scapular slide test is used to asses scapular dyskinesia
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Low Back Pain
Effect of Peripheral Magnetic Stimulation in Patients With Chronic Lower Back Pain
The aim of this study is to analyze the effect of Repeated Peripheral Magnetic Stimulation (rPMS) in patients with chronic low back pain. This is a controlled, randomized, multicenter clinical trial (Brazil x Portugal).
- Trial name
- PEMS-CLBP (NCT07243548)
- Testing
- rPMS Intervention, rPMS Controle
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Inês Gomes
Spinal Cord Injury
Chronic Pain and Brain Activity in Spinal Cord Injury
This study compares five different procedures to see how they affect pain and brain activity. The procedures include neurofeedback, self-hypnosis training, meditation, and two different levels of transcranial direct current…
- Trial name
- NCT01012635
- Testing
- Hypnosis, Meditation, Neurofeedback training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Washington
Chronic Low Back Pain, Chronic Neck Pain
Chronic Low Back Pain and Neck Pain Prospective Study
This prospective observation multifaceted study aims: 1. To perform a large prospective study and identify multiple "omics" biomarkers in chronic low back pain 2.
- Trial name
- NCT04883476
- Testing
- Observation study only
- Where
- Hong Kong
- Volunteers
- 800 people
- Sponsor
- The University of Hong Kong
Chronic Pain
Social & Behavioral Rhythms in Chronic Pain
Behavioral and biological rhythms are essential for health. No study evaluated behavioral rhythm or rhythm regulation in chronic pain and how this impacts functioning.
- Trial name
- NCT03022643
- Testing
- Interpersonal Social Rhythms Psychotherapy, Bright Light Device
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Utah
Breast Cancer, Postoperative Pain, Acute
Rhomboid Intercostal Plane Block on Chronic Pain Incidence and Acute Pain Scores After Mastectomy
Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. RIB has been reported to be successful in attenuating acute pain following breast surgeries.
- Conditions
- Breast Cancer, Postoperative Pain, Acute, Postoperative Pain, Chronic, Neuropathic Pain
- Trial name
- NCT06019325
- Testing
- RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 254 people
- Sponsor
- Muğla Sıtkı Koçman University
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