Clinical trials: Chronic Pain, completed
Carpal Tunnel Syndrome
Effects of Mirror Therapy on Pain and Function on Bilateral Carpal Tunnel Syndrom
The purpose of this study was to evaluate pain and function after mirror therapy as well as level of catastrophism in bilateral carpal tunnel syndrome patients
- Trial name
- MTSTC (NCT03169218)
- Testing
- Mirror therapy
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Olga Del Pozo Blanco
Temporomandibular Joint Disorders, Orofacial Pain
Occlusal Adjustment as Treatment for Chronic Orofacial Pain
The purpose of this study is to determine whether occlusal adjustment by selective grinding and/or occlusal addition is an effective treatment of chronic temporomandibular joint disorders.
- Trial name
- NCT00899717
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 21 people
- Sponsor
- University of Santiago de Compostela
Low Back Pain
Safety, Effectiveness, and Impact on Quality of Life on Long-Term Administration of OROS Hydromorphone Slow-Release in Patients With Chronic Low Back Pain
The purpose of this open-label, extension study is to characterize the safety, effectiveness, and impact on quality of life measures of long-term repeated dosing of OROS hydromorphone slow release (8, 16, 32 and 64 mg tablets) in…
- Trial name
- NCT00411268
- Testing
- OROS hydromorphone HCI SR (slow release)
- Volunteers
- 207 people
- Sponsor
- Alza Corporation, DE, USA
Chronic Neck Pain, Mechanical Neck Pain
Muscle Energy Technique Versus Myofascial Release in Chronic Non Specific Neck Pain
Chronic non-specific neck pain is a common musculoskeletal condition that can significantly affect daily activities, sleep quality, and overall quality of life.
- Trial name
- NCT07710950
- Testing
- Muscle Energy Technique, Myofascial Release Therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Low Back Pain
Anticipatory Muscle Control and Effect of Stabilizing Exercises in Patients With Subacute and Chronic Low Back Pain
Muscular stability is essential to the spinal column to avoid harmful strain and injury to its structures. Sudden postural disturbances impose reactive internal forces through the spine.
- Trial name
- NCT00201513
- Testing
- Isolated Transversus abdominis (TrA) exercise, sling exercise, group exercise
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Norwegian University of Science and Technology
Gynecologic Cancers, Postoperative Pain
Postoperative Chronic Pain in Gynaecological Cancer Surgery
The aim of this study was to determine the incidence of postoperative chronic pain in gynaecological cancer surgery and the analgesia methods used for postoperative analgesia.
- Trial name
- NCT07077889
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Knee Pain Chronic
Chronic Pain and Functional Prognosis After Total Knee Replacement: Continuous Locoregional Analgesia by Catheter to the Femoral Triangle Versus Tissue Infiltration as Part of an Improved Rehabilitation After Surgery Approach
The prevalence of Chronic Post-Surgical Pain (CPSP) after knee replacement, defined as pain greater than or equal to 4/10 on the visual analogue scale after the third postoperative month, is recognised as high, with an average of…
- Trial name
- TKAFTER (NCT03998813)
- Testing
- Ropivacaine
- Where
- 5 sites in France
- Volunteers
- 287 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Low Back Pain
Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1940
A Phase I, Multi-Centre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1940, Including an Interaction Study, After Administration of Oral Multiple Ascending…
- Trial name
- NCT00689780
- Testing
- AZD1940, Midazolam
- Where
- 3 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- AstraZeneca
Chronic Widespread Pain
The Role of Epigenetic Mechanisms in Stress Intolerance in Patients With Chronic Widespread Pain
Patients with chronic widespread pain (CWP) frequently experience stress intolerance - an exacerbation of symptoms in response to stress. Although it severely affects their quality of life, stress intolerance remains a mystery.
- Trial name
- EPISIP (NCT06475859)
- Testing
- Montreal Imaging Stress Test, Relaxation breathing
- Where
- Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Pain, Cognitive Impairment
Chronic Pain Self-management for Older Adults With Cognitive Impairment: A Randomized Pilot Trial
The goal of this randomized pilot trial is to test a chronic pain self-management program customized for people living with both chronic pain and cognitive impairment.
- Trial name
- STEPS-CI (NCT06182423)
- Testing
- STEPS-CI (Support, Training, and Education for Pain Self-management- Cognitively Inclusive version)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Michigan
Chronic Pancreatitis
Assessing the Utility of Cognitive Behavioral Therapy for Pain Control in Patients With Chronic Pancreatitis
This study will assess cognitive behavioral therapy as an adjunct to conventional symptom control for patients with chronic pancreatitis.
- Trial name
- NCT03112759
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Louisville
Pain
From Acute to Chronic Postoperative Pain in Patients for Elective Cholecystectomy. Immunological Tests
Chronic Pain after Cholecystectomy is a well known problem. One theory is that it is due to persisting inflammation. The purpose of the study is to measure inflammatory factors in cerebrospinal fluid and blod at patients 12…
- Trial name
- NCT01546480
- Where
- 2 sites in Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Exercise
Effect of Exercises on Pain, Functional Disability and Lumbar Stability in Patients With Low Back Pain
The purposes of this study are to compare the effects of core stabilization exercises on pain intensity, functional disability and lumbar stability between using and not using the Swiss ball in patients with non-specific chronic…
- Trial name
- NCT03527524
- Testing
- exercise with ball, exercise without ball
- Volunteers
- 28 people
- Sponsor
- Mahidol University
Chronic Low Back Pain
A Trial of Brief Physiotherapy Informed by Acceptance and Commitment Therapy for Chronic Low Back Pain: the PACT Study
Chronic low back pain (CLBP) is very common and causes much pain and disability. It costs the NHS billions of pounds in treatment every year and is the second leading cause of time off work.
- Trial name
- PACT (NCT02409420)
- Testing
- Physiotherapy informed by Acceptance and Commitment Therapy
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- King's College London
Non-radiographic Axial Spondyloarthritis
Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis
The purpose of this study was to evaluate the efficacy, safety, and tolerability of secukinumab in Chinese patients with active non-radiographic axial spondyloarthritis (nr-axSpA).
- Trial name
- NCT04732117
- Testing
- Secukinumab
- Where
- 29 sites in China
- Volunteers
- 137 people
- Sponsor
- Novartis Pharmaceuticals
Cardiac Surgery
Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Sternotomy
Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-sternoyomy pain syndrome (PSPS) ranges from 33% to 91%.
- Trial name
- NCT05885230
- Testing
- pecto intercostal fascial block using bupivacaine 0.25%, lidocaine infusion
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Chronic Pain
Efficacy of Yoga Based Self-Management Program for Chronic Pain
Chronic pain is a major health issue with substantial economic burden.To support chronic pain patients during the COVID-19 pandemic, yoga based self-managed intervention was delivered through tele-health platform.
- Trial name
- NCT04628130
- Testing
- Yoga Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- Aarogyam UK
Chronic Pain, Older Adults
Acceptance and Commitment Therapy and Exercise for Older Adults With Chronic Pain
The goal of this trial is to learn if combining Acceptance and Commitment Therapy (ACT) and exercise works to reduce pain intensity, pain interference, and depressive symptoms in older adults with chronic pain and depressive…
- Conditions
- Chronic Pain, Older Adults, Acceptance and Commitment Therapy, Exercise
- Trial name
- NCT05528536
- Testing
- Acceptance and Commitment Therapy (ACT), Art, Exercise
- Where
- Hong Kong
- Volunteers
- 163 people
- Sponsor
- The University of Hong Kong
Pain, Chronic
An Evaluation of a Public Health Campaign in a High School Setting Targeting Pain Related Knowledge and Beliefs
The beliefs held by students lead to behaviours in response to their pain which can be both helpful or a hindrance to how they manage their pain.
- Trial name
- NCT05636345
- Testing
- pain science education
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Teesside University
Inguinal Hernia, Chronic Pain
Trigger-point Blockade in Persistent Pain After Open Groin Hernia Repair
Groin hernia repair is a common procedure performed in approximately 2,000 patients per one million inhabitants. Severe chronic pain following groin hernia repair is seen in 2-5% of the patients indicating that a large number of…
- Trial name
- Trigger-open (NCT02065219)
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
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