Clinical trials: Chronic Pain, completed
Pain, Postoperative, Pain
The Adolescent Surgery Experience: A Mixed Methods Analysis
New chronic pain and opioid use are reported as prevalent among adolescents undergoing major surgery; many unanswered questions remain regarding recovery and the anticipated pain trajectory across procedures and the interaction…
- Conditions
- Pain, Postoperative, Pain, Pain, Acute, Pain, Chronic
- Trial name
- NCT05482919
- Testing
- Baseline Survey, Post Operative Surveys, Qualitative Interviews
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Children's Hospital of Philadelphia
Chronic Lateral Epicondylitis
Comparing the Effects of Manual Cross Friction Massage Versus Instrument-Assisted Soft Tissue Mobilization on Pain, Range of Motion, And Functional Disability in Patients With Chronic Lateral Epicondylitis
This was a randomized controlled trial done to to compare the effect of manual Cross Friction Massage and IASTM in reducing pain , range of motion and functional disability in patients with chronic lateral epicondylitis.
- Trial name
- NCT07695064
- Testing
- Manual Cross Friction Massage (CFM), Instrument-Assisted Soft Tissue Mobilization (IASTM)
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Ibadat International University, Islamabad
Osteoarthritis
Efficacy of Acupuncture With Physical Therapy for Knee Osteo-Arthritis
This study will examine the efficacy of acupuncture in combination with exercise physical therapy for moderate osteoarthritis (OA) of the knee.
- Trial name
- NCT00035399
- Testing
- Acupuncture
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Recurrent Low Back Pain
Mixed Reality Gaming for Chronic Low Back Pain
Mixed Reality Gaming for Chronic Low Back Pain
- Trial name
- NCT03603028
- Testing
- Exergaming
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Alabama at Birmingham
Chronic Apical Periodontitis
Comparison of the Effects of N-acetylcysteine, Calcium Hydroxide, and Double Antibiotic Paste
This study aimed to evaluate the efficacy of N-acetylcysteine (NAC) used as an intracanal medicament on antibacterial activity, periapical RANKL/OPG ratio, and postoperative pain levels.
- Trial name
- NCT07340944
- Testing
- N Acetyl Cysteine, Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Degenerative Disc Disease
AMG0103 in Subjects With Chronic Discogenic Lumbar Back Pain
This clinical trial evaluate the safety, tolerability and exploratory efficacy of targeted single injection of AMG0103 in subject with chronic discogenic lumbar back pain
- Trial name
- NCT03263611
- Testing
- AMG0103
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- AnGes, Inc.
Chronic Pain
Pain and Function After Orthopedic Surgery
The purpose of this study is to provide preliminary data for a Program Project Grant to the National Institutes of Health to examine specific explanations regarding identifying patients at risk for chronic pain after surgery and…
- Trial name
- NCT01390298
- Testing
- Observational
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Wake Forest University
Chronic Shoulder Pain
Assessment of Effectiveness of Dry Needling for Treating Shoulder Pain
The aim of the study is to evaluate the effects of active dry needling (aDN) in the treatment of myofascial trigger points of the infraspinatus muscle (MTP).
- Trial name
- NCT05137106
- Testing
- Active Dry Needling
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- University of Gran Rosario
Shoulder Pain, Rotator Cuff Syndrome
Tactile Acuity, Right-left Discrimination, and Motor Imagery in Chronic Rotator Cuff-related Shoulder Pain
A common finding in various chronic musculoskeletal pain conditions is changes in the cortical sensorimotor region. Functional brain changes associated with chronic pain include changes in the working body schema and associated…
- Trial name
- NCT06503549
- Testing
- Assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Acibadem University
Musculoskeletal Diseases, Work-Related Condition
Individuals With Chronic Work-related Musculoskeletal Disease a Multidisciplinary Care Program
Rehabilitation for work-related musculoskeletal disorders involves physical, behavioral, psychological treatment and counseling on how to deal with pain and disability.
- Conditions
- Musculoskeletal Diseases, Work-Related Condition, Chronic Pain
- Trial name
- NCT05150730
- Testing
- Multi professional care
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Cidade de Sao Paulo
Lumbar Disc Degeneration, Lumbar Disc Disease
Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement
Lumbosciatica is a very prevalent pathology. When conservative treatments fail, surgery should be considered. The traditional surgical treatment is lumbar arthrodesis.
- Conditions
- Lumbar Disc Degeneration, Lumbar Disc Disease, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06989632
- Testing
- Total lumbar disc prosthesis (Baguera®L, Spineart, Switzerland)
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- University of Valencia
Chronic Pain
Virtual Reality in Inpatients
This study is being conducted as a pilot to test the feasibility, usability, acceptability, and clinical utility of using a virtual reality (VR) immersion experience in the inpatient setting.
- Trial name
- NCT02456987
- Testing
- Samsung Gear
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cedars-Sinai Medical Center
Multiple Sclerosis, Pain
Usability of the MeTime MS App
The Me Time MS Application was designed to enable self-administration of acupressure. Two forms of acupressure - either "relaxing" or "stimulating" protocols - are administered through the Me Time MS app.
- Conditions
- Multiple Sclerosis, Pain, Fatigue Symptom
- Trial name
- NCT07123272
- Testing
- Self-guided smartphone application for relaxing acupressure, Self-guided smartphone application for stimulating acupressure
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Covid19
Efficacy of Adaptogens in Patients With Long COVID-19
The aim of this clinical trial of a fixed combination of standardized extracts from Rhodiola rosea roots, Schisandra chinensis berry and Eleutherococcus senticosus root (ADAPT-232) in COVID-19 patients is to demonstrate possible…
- Trial name
- NCT04795557
- Testing
- ADAPT-232 oral solution
- Where
- Georgia
- Volunteers
- 100 people
- Sponsor
- Swedish Herbal Institute AB
Chronic Low-back Pain
Personalized Auricular Vagus Nerve Stimulation in Intractable Chronic Low Back Pain
One in five people in the general adult population suffer from chronic pain, a figure that is higher than heart disease, cancer, and diabetes combined. A majority of these patients is suffering from chronic back pain.
- Trial name
- AuriMod (NCT04753528)
- Testing
- AuriMod CT01_A, AuriMod CT01_B, AuriMod CT01_C
- Where
- 2 sites in Austria, Switzerland
- Volunteers
- 43 people
- Sponsor
- Aurimod GmbH
Non-specific Chronic Low Back Pain, Healthy Volunteer
Behavioral Indicators of Pain Representation
The goal of this observational study is to compare the postural response to the mental simulation of everyday situations identified as painful in participants with non-specific low back pain and healthy volunteers.
- Trial name
- ICOR (NCT06669767)
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universite de Picardie Jules Verne
Chronic Low Back Pain (CLBP)
A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population
Low back pain is a common problem that many adults experience at some point in their lives. One treatment being studied is dry needling, a technique where a small needle is inserted into a specific area of muscle to help relieve…
- Trial name
- NCT06940492
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Sexual Dysfunction, Hernia, Inguinal
Pain Related Sexual Dysfunction After Laparoscopic Inguinal Hernia Repair
Previous studies have reported that about 3 % of patients who have had open inguinal herniorrhaphy had a visceral, ejaculatory-related pain.
- Conditions
- Sexual Dysfunction, Hernia, Inguinal, Other Chronic Postoperative Pain
- Trial name
- NCT01086007
- Where
- Denmark
- Volunteers
- 1,172 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neck Pain
Chronic Neck Pain and Central Sensizitation
Chronic neck pain is one of the musculoskeletal pain problems that can cause chronic disability. It is emphasised that individuals with chronic neck pain have difficulty during different activities in their daily lives, and that…
- Trial name
- NCT06976398
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Degenerative Disc Disease
Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back Pain
The purpose of this study is to compare two doses of immunoselected, culture-expanded, nucleated, allogeneic adult MPCs when combined with hyaluronic acid to two control intradiscal injections in subjects with chronic low back…
- Trial name
- NCT01290367
- Testing
- Single Dose MPCs Injection, Single injection of saline solution, Single injection of hyaluronic acid
- Where
- 14 sites in United States, Australia
- Volunteers
- 100 people
- Sponsor
- Mesoblast, Ltd.
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