Clinical trials: Chronic Pain, completed
Chronic Low-back Pain (cLBP)
Virtual Reality Based High-intensity Interval Training in Chronic Low Back Pain
One of the most prevalent causes of pain on a global scale is chronic musculoskeletal pain. Low back pain is a prevalent manifestation of chronic musculoskeletal pain.
- Trial name
- NCT07388134
- Testing
- Virtual reality based high intensity interval training (VR-HIIT) group, High intensity interval training (HIIT) group
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Universidad de Granada
HIV, Peripheral Neuropathy
OPEN Study: Pain Management Treatment Needs Interviews
Presently, there are few options for medically managing HIV-related painful peripheral sensory neuropathy (HIV-SN). Psychological treatments, including Cognitive Behavioural Therapy (CBT), represent a potentially viable addition…
- Trial name
- NCT02972606
- Where
- 2 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- King's College London
Chronic Pain
OTR Tablet 10 mg Fasted-state Bioequivalence Study
This is an open-label, single Dose, randomised, cross-over study to confirm the bioequivalence (BE) of OTR tablet 10 mg and OXYCONTIN tablet 10 mg in a fasted state in Chinese subjects with chronic pain
- Trial name
- NCT03403504
- Testing
- Oxycodone Tamper Resistant, OXYCONTIN®
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Chronic Low Back Pain
A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Low Back Pain
Patients with Chronic Axial Low Back Pain participated in a Phase II clinical trial to assess the efficacy of lidocaine 5% patch compared with placebo.
- Trial name
- NCT00904111
- Testing
- Lidoderm®
- Where
- 18 sites in United States
- Volunteers
- 215 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Neck Pain
Effect of Proprioceptive Exercises on Pain and Function in Non-specific Chronic Neck Pain
This study was conducted to see the effect of proprioceptive exercises on pain and function in Non-specific chronic neck pain. Twenty participants with chronic Non-specific neck pain were enrolled in this study.
- Trial name
- NCT05092334
- Testing
- proprioceptive exercises, Strengthening exercise
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Riphah International University
Critical Limb Ischemia, Peripheral Arterial Disease
ALD-301 for Critical Limb Ischemia, Randomized Trial
This study will treat patients with such severe lower leg ischemia or vascular compromise that they have pain at rest. The goal is to compare treatment of the patient's painful disorder by injecting cells into the calf of the leg…
- Conditions
- Critical Limb Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease
- Trial name
- CLI-001 (NCT00392509)
- Testing
- ALDH-br bone marrow cells vs. mononuclear bone marrow cells
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Aldagen
Hypermobility Syndrome Shoulder, Shoulder Pain Chronic
Shoulder Exercises in Hypermobile Patients With Shoulder Symptoms
Hypermobility Spectrum Disorder (HSD) is a recent diagnosis that covers generalised joint hypermobility with one or more secondary symptomatic musculoskeletal manifestations.
- Conditions
- Hypermobility Syndrome Shoulder, Shoulder Pain Chronic, Shoulder Luxation
- Trial name
- NCT03869307
- Testing
- Exercise
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Southern Denmark
Chronic Low Back Pain
Study of Basivertebral Nerve Ablation Treatment of Chronic Low Back Pain
Prospective, single arm, open label, multi-center study to evaluated the effectiveness of intraosseous basivertebral nerve radiofrequency ablation using the Intracept System.
- Trial name
- NCT03266107
- Testing
- Intracept
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Relievant Medsystems, Inc.
Osteo Arthritis Knee, Chronic Pain
Addition of Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation to an Education and Exercise Program in Subjects With Chronic Pain Due to Knee Osteoarthritis
Knee osteoarthritis has a very high prevalence in the population over 50 years of age. Patients with osteoarthritis often suffer from chronic pain that becomes disabling, affecting both quality of life and mental and physical…
- Trial name
- NCT05138471
- Testing
- transcranial direct current stimulation (tDCS), TENS, Exercise and General Education
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Universidad de Murcia
Inappropriate Dose of Drug Administered, Pain, Chronic
Trial Applying Policy to Eliminate or Reduce Inappropriate Narcotics in the General-population
To assess the effectiveness of a government-led population-based opioid intervention on discontinuation of opioid medication in community-dwelling adults with chronic non-cancer pain.
- Conditions
- Inappropriate Dose of Drug Administered, Pain, Chronic, Health Behavior
- Trial name
- TAPERING (NCT03400384)
- Testing
- Direct-to-consumer educational brochure
- Where
- Canada
- Volunteers
- 4,255 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Neck Pain
Effectiveness of Transcutaneous Electrical Nerve Stimulation and Interferential Current in Chronic Neck Pain
The aim of this study was to determine and compare the efficacy of transcutaneous electrical nerve stimulation (TENS), interferential current (IFC), and sham therapy in patients with chronic neck pain.
- Trial name
- NCT07780747
- Testing
- TENS, IFC
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Beylikduzu State Hospital
Chronic Insomnia
Mobile Sleep Intervention for OEF, OIF and OND Veterans
Many Veterans of the recent wars in Iraq and Afghanistan struggle with chronic insomnia (trouble falling or staying asleep). Most current interventions for insomnia are time-consuming, making it difficult for this younger…
- Trial name
- NCT02392000
- Testing
- WatchPAT sleep monitor, CBT-i Coach mobile app
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Carpal Tunnel Syndrome, Pain, Chronic
Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain
This randomized, assessor-blinded, parallel-group trial evaluated the effectiveness of adding a psychologically informed pain-management intervention to standardized physical rehabilitation in adults with electrodiagnostically…
- Trial name
- NCT05915611
- Testing
- Standardized Carpal Tunnel Syndrome Rehabilitation, Psychologically Informed Pain-Management Program, Attention-Matched Health Education
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Ahram Canadian University
Low Back Pain
Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain
To demonstrate clinically significant improvements or lack thereof in the caudal epidural patients with our without steroids. To evaluate differences in outcomes in patients receiving steroids compared to those patients…
- Trial name
- NCT00370799
- Testing
- Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Pain Management Center of Paducah
Chronic Pain
Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids
There are nearly one million veterans being treated with long-term opioid therapy (LTOT) for chronic pain. Numerous short and long-term harms associated with LTOT and mounting evidence suggest they have modest or no benefit.
- Trial name
- NCT04746833
- Testing
- SUMMIT, control
- Where
- 4 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Atrial Fibrillation, Neuropathic Pain
Atrial Fibrillation and Neuropathic Pain After Thoracotomy and Continuous Application of Magnesium Sulphate.
Atrial fibrillation and chronic neuropathic pain are adverse events occurring after posterolateral thoracotomy for lung resection. The continuous application of magnesium sulphate may have a prophylactic effect.
- Trial name
- NCT02008747
- Testing
- Magnesium sulphate
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Chronic Pain
Acceptability of an Acupuncture Intervention in Painful Elderly
The aim is to investigate the feasibility and efficacy of an acupuncture intervention on persistent MusculoSkeletar pain in a long-term geriatric hospital care ward population.
- Trial name
- ACUPUNCTURE (NCT01043692)
- Testing
- Acupuncture
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain, Cancer
Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
This study seeks to explore the efficacy of immersive multimedia experiences as a practical adjunctive therapeutic intervention in the self-management of the chronic pain associated with cancer patients.
- Trial name
- NCT02995434
- Testing
- Virtual Reality Headset, 2D PC
- Where
- 3 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Neck Pain
Neck Education for Parents of Disabled Children
Objective: Parents of children with disabilities are at risk of musculoskeletal pain, postural disorders, and functional limitations due to caregiving responsibilities and physical demands.
- Trial name
- NCT06758232
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Ankle Sprains, Chronic Pain
Effects of Closed Chain Exercise Versus Neuromuscular Training on Chronic Ankle Sprain in Football Players
A current study will be conducted to determine the effects of closed-chain exercise versus neuromuscular training on pain, range of motion, and functional performance in football players with a chronic ankle sprain.
- Trial name
- NCT05981560
- Testing
- Group A - Closed Chain Exercise, Group B - Neuromuscular Training Exercise
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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