Clinical trials: Chronic Pain, completed
Osteoarthritis, Low Back Pain
An Efficacy and Safety Study of Fentanyl Transdermal Patch in Filipino Participants With Osteoarthritis and Chronic Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of fentanyl among Filipino participants with osteoarthritis (disorder which is seen mostly in older persons in which the joints become painful and stiff) and…
- Trial name
- NCT01795898
- Testing
- Fentanyl
- Where
- Philippines
- Volunteers
- 237 people
- Sponsor
- Janssen Pharmaceutica
Elderly, Chronic Pain
Characterization of Chronic Pain in Elderly Population With Emphasis on Differences Between Gender
Introduction: It is estimated that by 2025 there will be approximately 1.2 billion people above 60 years old. Global projections indicate that by 2050 there will be about 2 billion elders, 80% of them living in developing…
- Conditions
- Elderly, Chronic Pain, Gender
- Trial name
- NCT06855797
- Testing
- Observation
- Where
- Brazil
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Chronic Low-back Pain, Low Back Pain
Virtual Reality-based Induction to Improve Positive Body Image in Low Back Pain Patients.
The aim of this study is to examine the effects of a Virtual Reality-based induction to modify positive body image in individuals with low back pain.
- Trial name
- NCT06054074
- Testing
- Positive Appreciation of Body Functionality Induction, Negative Appreciation of Body Functionality Induction
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- University of Valencia
Amputation, Chronic Pain
Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain
Persistent pain occurs in 50-85 percent of patients who experience the amputation of an extremity. This study will compare the effectiveness of morphine and mexiletine to placebo in the treatment of postamputation pain.
- Trial name
- NCT00383682
- Testing
- morphine and mexiletine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Chronic Low Back Pain
Intra- And Inter-operator Reliability Of Isometric Back And Abdominal Muscle Strength Testing In Healthy Controls And Persons With Nonspecific Chronic Low Back Pain.
Low back pain (LBP) is currently the most common cause of functional impairment with regard to the musculoskeletal system1. LBP occurs in men and women in all age groups and has a peak incidence between 30 and 65 years.
- Trial name
- LBP-BIO-REL (NCT03571880)
- Testing
- Biodex-assisted isometric strength testing
- Where
- 2 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Pain, Chronic
Effectiveness and Safety of tDCS for Pain
The purpose of this study is to verify the effectiveness and safety of transcranial direct current stimulation in patients with central post-stroke pain.
- Trial name
- NCT05612165
- Testing
- Transcranial Direct Current Stimulation(tDCS)
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Pusan National University Yangsan Hospital
Ilioinguinal Nerve Block
The Effects of Ilioinguinal Nerve Block on Chronic Pain in Patients in Inguinal Hernia With Spinal Anesthesia
Regional anesthesia is a popular anesthetic method in patients who will undergo an inguinal hernia operation. Researchers known that pain in the operating area is a complaint that impairs the quality of life for patients in the…
- Trial name
- NCT04295629
- Testing
- Research on the effects of Ilioinguinal Nerve Block on Chronic Pain in Patients who undergo Inguinal Hernia with Spinal Anesthesia, Ilioinguinal nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Low Back Pain, Kinesiophobia (Fear of Movement)
Feasibility of an Augmented Reality Novel Approach for the Rehabilitation of Chronic Low Back Pain Patients With Kinesiophobia
The goal of this clinical trial is to evaluate the feasibility, safety, and initial effectiveness of a new augmented reality (AR) system in adults over 18 years old suffering from chronic low back pain and kinesiophobia (fear of…
- Conditions
- Low Back Pain, Kinesiophobia (Fear of Movement), Healty Volunteers
- Trial name
- NCT07527845
- Testing
- Augmented Reality (AR) Rehabilitation System
- Where
- Chile
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Chronic Pain, Recurrences
Comparison of Three Meshes in Lichtenstein Hernia Repair
Chronic pain may be a long-term problem after inguinal Lichtenstein hernioplasty. The aim of this study was to compare long-term results of hernioplasty using three different meshes (partly absorbable, lightweight polypropylene…
- Trial name
- Lichtenstein (NCT01295437)
- Testing
- Vypro II mesh, Premilene LP, Premilene mesh
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Cystic Fibrosis
Impact of Global Care of the Pain at Chronic Painful Patients Affected by Cystic Fibrosis
The purpose of this study is to evaluate the impact of the global approach to the pain in cystic fibrosis patients with chronic or intermittent pain.
- Trial name
- MUCO-SOPHRO (NCT01915875)
- Testing
- sophrology sessions at home
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus Type 2 Without Complication, Polyneuropathies, Diabetic
Polyneuropathy in Diabetes Mellitus Type 2
This is a population-based study of type 2 diabetes patients with and without neuropathy recruited from the Danish National Type 2 Diabetes cohort (DD2).
- Conditions
- Diabetes Mellitus Type 2 Without Complication, Polyneuropathies, Diabetic, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- NCT02947828
- Where
- 2 sites in Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Chronic Low Back Pain
The Effects of Apomorphine on Experimental and Clinical Pain in Patients With Chronic Radicular Pain
The study aimed to explore the effect of the dopamine agonist apomorphine on spontaneous pain intensity and evoked cold clinical and experimental pain in patients with lumbar radicular neuropathic pain (NP).
- Trial name
- NCT02969629
- Testing
- Apomorphine, Normal Saline
- Where
- Israel
- Volunteers
- 59 people
- Sponsor
- Rambam Health Care Campus
Ultrasound Therapy; Complications, Low Back Pain
Therapeutic Ultrasound on Renal Function
This study evaluates whether therapeutic ultrasound (TUS) treatment applied to lumbar region with chronic low back pain affect renal function.
- Trial name
- NCT03746639
- Testing
- physiotherapy modalities
- Volunteers
- 40 people
- Sponsor
- Alper Mengi
Inguinal Hernia, Inguinal Hernia Repair
Comparative Study of Inguinodynia After Inguinal Hernia Repair
To evaluate the postoperative pain and the relapse after the repair of the inguinal hernia by Lichtenstein technique with four different mesh types with different types of fixation in patients undergoing major ambulatory surgery.
- Conditions
- Inguinal Hernia, Inguinal Hernia Repair, Open Inguinal Hernia
- Trial name
- NCT03678272
- Testing
- HERNIOPLASTY WITH PANAVALE MESH, HERNIOPLASTY WITH PARIETEX PROGRIP MESH, HERNIOPLASTY WITH ADHESIX MESH
- Volunteers
- 270 people
- Sponsor
- Hospital General Universitario Elche
Chronic Low Back Pain
Efficacy of Education on Neurophysiology of Pain Combined to Hypnosis in Patients With Chronic Low Back Pain
Although education on neurophysiology of pain improves disability, there are limited effects in pain intensity. Hypnosis is an approach that has proven useful in pain intensity and psychosocial aspects in some chronic pain…
- Trial name
- NCT02638753
- Testing
- education, education combined with hypnosis
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Universidade Cidade de Sao Paulo
Chronic Low-back Pain (cLBP)
The Effect Of Kinesiotape Application In Chronic Low Back Pain
This study was conducted to determine the effects of kinesiotaping (KT) and sham KT applied with exercise program on clinical parameters such as pain, sleep, and quality of life in postmenopausal women with chronic low back pain.
- Trial name
- NCT06684145
- Testing
- Kinesiotape application, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Firat University
Diabetic Peripheral Neuropathic Pain
A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
The primary purpose of this study is to evaluate the safety and efficacy of medical cannabis aerosol containing 0.25, 0.50, 1.0 milligrams (mg) delta (Δ) 9-tetrahydrocannabinol (THC) inhaled three times a day (TID) compared to…
- Trial name
- NCT06490445
- Testing
- Medical Cannabis
- Where
- 38 sites in Australia, Czechia and 3 more
- Volunteers
- 122 people
- Sponsor
- Syqe Medical
Chronic Pain Syndrome, Opioid Use
Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain
The primary aim of this pilot trial is to enhance the efficacy of the Mindfulness-Oriented Recovery Enhancement (MORE) intervention by adding neurofeedback (NF) of the Orbitofrontal Cortex (OFC) as an adjunct to the savoring…
- Trial name
- NCT04902339
- Testing
- Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Utah
Chronic Pain, Analgesics, Opioid
Tapering From Long-term Opioid Therapy in Chronic Pain Population. Randomized Controlled Trial With 12 Months Follow up
This randomized controlled study compares tapering of long-term opioid therapy in a population with chronic non-cancer pain with control group constituted of waiting list.
- Conditions
- Chronic Pain, Analgesics, Opioid, Opioid Withdrawal, Opioid Use
- Trial name
- TOPIO (NCT03485430)
- Testing
- Tapering
- Where
- 3 sites in Sweden
- Volunteers
- 140 people
- Sponsor
- Lund University Hospital
Chronic Nonspecific Low Back Pain
Vacuum Myofascial Therapy Device and Physical Activity for the Treatment of Chronic Non-specific Low Back Pain. A Single Blind Randomized Clinical Trial
The term non-specific low back pain refers to the painful symptoms located in the lumbar region, which is delimited between the lower margin of the ribs and the lower limit of the buttocks
- Trial name
- NCT04534179
- Testing
- Vacuum myofascial therapy and physical activity program., Physical activity program.
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Cadiz
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