Clinical trials: Chronic Pancreatitis
Pancreatic Cancer, Pancreatitis
Validation of Joint-AI in Diagnosing Pancreatic Solid Lesions
This clinical trial aims to learn if a multimodal artificial intelligence (AI) model can enhance the diagnosis of pancreatic solid lesions. The main questions it aims to answer are: 1.
- Conditions
- Pancreatic Cancer, Pancreatitis, Pancreatic Neuroendocine Neoplasms (pNETs), Autoimmune Pancreatitis
- Trial name
- NCT06753318
- Testing
- The assistance of the Joint-AI model, The assistance of the interpretable Joint-AI model
- Where
- China
- Volunteers
- 716 people
- Sponsor
- Huazhong University of Science and Technology
Chronic Pancreatitis, Type 2 Diabetes Mellitus
The Incretin Effect in Patients With Chronic Pancreatitis
The phenomenon that oral glucose elicits a higher insulin response than does intravenous (iv) glucose, even at identical plasma glucose (PG) profiles (isoglycemia), is called the incretin effect.
- Trial name
- NCT00638573
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Chronic Pancreatitis
Endoscopic Ultrasound Compared With Pancreatic Function Testing for Diagnosis of Chronic Pancreatitis
This is a investigator-initiated, single-center, prospective study to evaluate endoscopic ultrasound (EUS) as a diagnostic test for chronic pancreatitis (CP).
- Trial name
- NCT00651053
- Testing
- EUS
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
SIBO, Pancreatic Insufficiency
Breath Test-Based Assessment of SIBO in Chronic Pancreatitis and Partial Pancreatectomy
Pancreatic exocrine insufficiency (PEI) results from reduced pancreatic enzyme secretion, leading to malabsorption, malnutrition, and impaired quality of life.
- Conditions
- SIBO, Pancreatic Insufficiency, Chronic Pancreatitis, Pancreatic Surgey
- Trial name
- DCP-PCT-EPI (NCT07479238)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Mesenchymal Tumor, Autoimmune Pancreatitis
Evaluation of a New EUS Guided Biopsy Needle (SharkCore) Comparing to Standard EUS Needle (ProCore)
Diagnosis of lesions of pancreas, the upper gastrointestinal tract, as well as adjacent structures, such as lymph nodes, is still showing advancements especially with the increased use of endoscopic ultrasound.
- Conditions
- Mesenchymal Tumor, Autoimmune Pancreatitis, Lymphoma, Solid Tumors
- Trial name
- NCT02766842
- Testing
- EUS-FNB with ProCore needle, EUS-FNB with SharkCore needle, ProCore needle
- Where
- United States
- Sponsor
- Johns Hopkins University
Chronic Pancreatitis
Ivacaftor Impact in an Adolescent Without a Cystic Fibrosis-Associated CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Mutation for Chronic Pancreatitis: Single-Patient Study Tracking Flare Frequency and Health Data Compared to Historical Records.
The goal of this observational study is to learn about the long-term effects of Ivacaftor in an adolescent without a cystic fibrosis-associated CFTR mutation who is taking Ivacaftor to treat chronic pancreatitis.
- Trial name
- IMPACT (NCT07022327)
- Testing
- Ivacaftor 150 MG (milligrams)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mission: Cure
Hypertriglyceridemia, Familial
Safety Evaluation of Gene Therapy Drug in the Treatment of Primary Hypertriglyceridemic Patients With Recurrent Pancreatitis
The study will evaluate safety and tolerance of intravenous delivery of GC304 gene therapy drug as a treatment of primary hypertriglyceridemic patients with previous onset of acute pancreatitis.
- Trial name
- NCT05860569
- Testing
- GC304
- Where
- China
- Volunteers
- 7 people
- Sponsor
- GeneCradle Inc
Exocrine Pancreatic Insufficiency, Chronic Pancreatitis
A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects
The purpose of this study is to collect pancreas fluid from the duodenum using the endoscopic pancreas function collection method in healthy participants after pancreatic stimulation with human secretin.
- Trial name
- NCT07285863
- Testing
- Secretin (human synthetic) - ChiRhoClin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Pancreatitis, Malabsorption Syndromes
Vitamin D Substitution for Patients With Chronic Pancreatitis and Malabsorption
Purpose: The overall objective of this study is to learn more about the disease chronic pancreatitis and thus contribute to better treatments.
- Trial name
- NCT01141998
- Testing
- Calcium, Dietary, Cholecalciferol, UVB
- Where
- Denmark
- Volunteers
- 27 people
- Sponsor
- Hvidovre University Hospital
Chronic Pancreatitis, Pancreatic Exocrine Insufficiency
Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function Tests
The goal of this observational study is to improve the epidemiological data of pancreatic exocrine insufficiency in China, determine the FE-1 cut-off value for the classification of PEI, and explore the characteristic differences…
- Conditions
- Chronic Pancreatitis, Pancreatic Exocrine Insufficiency, Diabetes Mellitus, Community Populations
- Trial name
- NCT06006312
- Testing
- fecal elastase-1 test, 72-hour fecal fat quantification, blood sample test
- Where
- China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Study on Predictive Factors, Safety and Efficacy of Endoscopic Retrograde Accessory Pancreatography in CP
Chronic pancreatitis (CP) can manifest characteristic pathological modifications such as pancreatic duct stenosis and pancreatic duct lithiasis.
- Trial name
- NCT06684301
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis, Chronic Pain
Extracorporeal Shock Wave Lithotripsy and Endotherapy for Pain in Chronic Pancreatitis
Pain is a common symptom of chronic pancreatitis and remains a significant therapeutic challenge. In patients with pathological changes of the pancreatic duct, including stones and strictures, endoscopic procedures with or…
- Trial name
- SCHOKE (NCT03966781)
- Testing
- ESWL, ERCP
- Where
- India
- Volunteers
- 106 people
- Sponsor
- Asian Institute of Gastroenterology, India
Post-ERCP Acute Pancreatitis
Incidence and Risk Factor of Post-ERCP Pancreatitis in Chronic Pancreatitis
The purpose of this study is to compare the incidence of post-ERCP pancreatitis (PEP) in chronic pancreatitis (CP) patients to that in biliary disease patients, to determine whether CP patients in early clinical stage have a…
- Trial name
- NCT02781987
- Testing
- chronic pancreatitis
- Volunteers
- 2,028 people
- Sponsor
- Changhai Hospital
Pancreatitis, Pancreatic Neoplasms
Follow-up Study of Complications of Acute Pancreatitis
This is a follow-up study focusing on long-term complications of acute pancreatitis. The primary purposes include: 1. To assess the incidence of type 2 diabetes mellitus（2-DM）,impaired glucose tolerance, metabolic abnormalities…
- Conditions
- Pancreatitis, Pancreatic Neoplasms, Metabolic Diseases, Hypertension, Portal
- Trial name
- FSCAP (NCT02305914)
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Pancreatitis, Chronic, Pancreatic Duct Stone
Aggressive Intravenous Hydration With Lactated Ringer's Solution for Prevention of Post-ESWL Pancreatitis
The goal of this clinical trial is to clarify whether aggressive intravenous hydration with lactated Ringer's solution could reduce the incidence of post-ESWL pancreatitis in patients with chronic pancreatitis.
- Trial name
- HYPER (NCT05772234)
- Testing
- Lactated ringers solution, normal saline
- Where
- China
- Volunteers
- 1,066 people
- Sponsor
- Changhai Hospital
Islet Cell Tumor, Pancreatic Cancer
Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders
RATIONALE: Gathering medical information and collecting and storing samples of blood and tissue to test in the laboratory may help doctors develop better ways to screen people at risk for pancreatic cancer or other pancreatic…
- Conditions
- Islet Cell Tumor, Pancreatic Cancer, Pancreatic Disease, Acute Pancreatitis
- Trial name
- NCT00830557
- Testing
- medical chart review, survey administration, biospecimen collection
- Where
- 3 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Mayo Clinic
Pancreatitis, Chronic, Pancreatic Duct Stone
Comparison of Efficacy of ESWL and Laser Lithotripsy in Chronic Pancreatitis With ERCP
This study will compare the efficacy of ESWL and Laser Lithotripsy in the treatment of pancreatic duct stones with ERCP.
- Trial name
- NCT05326542
- Testing
- ESWL and ERCP, LL and ERCP
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital
IPMN, Pancreatic, Pancreatic Cancer, Resected
Venous Resection in Patients Undergoing Pancreatic Surgery
Pancreatic surgery is the only treatment in the multimodality approach to pancreatic cancer sine qua non long-term survival cannot be achieved.
- Conditions
- IPMN, Pancreatic, Pancreatic Cancer, Resected, Pancreatic Cancer Borderline, Chronic Pancreatitis
- Trial name
- VENUS (NCT07621029)
- Where
- 2 sites in Netherlands, Sweden
- Volunteers
- 1,000 people
- Sponsor
- Sahlgrenska University Hospital
Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic
Artificial Intelligence in EUS for Diagnosing Pancreatic Solid Lesions
We aim to develop an EUS-AI model which can facilitate clinical diagnosis by analyzing EUS pictures and clinical parameters of patients.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic, Pancreatic Neuroendocrine Tumor, Autoimmune Pancreatitis
- Trial name
- NCT05476978
- Testing
- EUS-AI model
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology