Clinical trials: Chronic Primary Pain
Headache Migraine Chronic
Spectacle Tints and Thin-Films for Migraine
Nearly all migraine sufferers report sensitivity to light during a headache and a significant proportion of sufferers report light sensitivity between attacks. Light is also a common trigger for migraine headaches.
- Trial name
- NCT02720211
- Testing
- Gray tinted spectacle lenses, Thin-Film spectacle lenses
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Nociplastic Pain, Chronic Primary Pain
Pain Reprocessing Therapy for Chronic Primary Pain
Approximately 30% of adult Norwegians experience chronic pain, with its prevalence rising across demographics, including children and adolescents Chronic pain contributes to significant personal suffering and substantial societal…
- Trial name
- PRIME-PRT (NCT07287072)
- Testing
- Pain Reprocessing Therapy
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- University of Oslo
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Migraine, Episodic Migraine
Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine
The goal of this observational study is to evaluate clinical differences in patients who received preventive treatment with medication targeting calcitonin gene-related peptide (CGRP) or its receptor: monoclonal antibodies…
- Conditions
- Migraine, Episodic Migraine, Chronic Migraine, Headache
- Trial name
- EUREkA (NCT07159750)
- Testing
- CGRP antibody or gepant
- Where
- 26 sites in United States, Argentina and 11 more
- Volunteers
- 700 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Chronic Musculoskeletal Pain
PainTrain-AI Pilot: Feasibility, Usability (SUS) and Concept-Shift in Primary Care and a Specialized Setting
This pilot will assess feasibility and usability (SUS) and explore concept shift (reduction of neurophysiology misconceptions) after exposure to a behavioral educational intervention (PainTrain AI), a digital clinical simulation…
- Trial name
- PT-AI Pilot (NCT07497997)
- Testing
- PainTrain-AI Behavioral Training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francesc Valenzuela Pascual
Chronic Pain, Central Sensitisation
Clinical Trial on Deprescribing Associated With a Psychoeducational Program Using Virtual Reality for Patients With Chronic Pain and Central Sensitization
This clinical trial evaluates the effectiveness of the REDOCVR program, an interdisciplinary, psychoeducational intervention designed to support deprescribing of chronic pain medications in primary care.
- Conditions
- Chronic Pain, Central Sensitisation, Opioid-Related Disorders, Patient Empowerment
- Trial name
- REDOCVR_AC (NCT06964360)
- Testing
- REDOCVR Psychoeducational Program, Standard Educational Materials
- Where
- 4 sites in Spain
- Volunteers
- 174 people
- Sponsor
- Badalona Serveis Assistencials
Fibromyalgia, Fibromyalgia (FM)
The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients
The goal of this clinical trial is to learn if a traditional grape-based fermented drink called hardaliye helps treat fibromyalgia in adult women.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome, Primary
- Trial name
- NCT07403929
- Testing
- Medical Nutrition Therapy (MNT), Hardaliye (200 mL/day)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Migraine, Migraine in Adolescence
Mindfulness-Based Intervention for Adolescents With Chronic Migraine
The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on…
- Trial name
- NCT06414109
- Testing
- BREATHE-Migraine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Pain, Chronic Primary
Pain and Clinical Reflections in Pelvic Congestion Syndrome
Pelvic congestion syndrome (PKS) occurs as a result of dysfunction of the veins in the pelvic area. It is currently called pelvic venous disease.
- Trial name
- NCT06507267
- Testing
- Pain and Clinical Reflections in Pelvic Congestion Syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Headache, Cephalgia
Effect of Osteopathic Manipulative Treatment for Patients With Chronic Headache
Participants with chronic or recurrent headache, unrelated to any known pathology or disease, will be randomly assigned to one of four interventions: Osteopathic manipulation of the body other than the head, osteopathic…
- Conditions
- Headache, Cephalgia, Migraine
- Trial name
- OMTHA (NCT01332864)
- Testing
- Osteopathic Manipulative Treatment (OMT), Light touch
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Western University of Health Sciences
Headache, Migraine
Psychological Assessment and Treatment of Chronic Benign Headache
Subjects with chronic migraine or tension headaches will receive 12 sessions of biofeedback or relaxation training after fulfilling screening, intake interviews, \& psychological testing requirements.
- Conditions
- Headache, Migraine, Tension Headache, Stress Headache
- Trial name
- NCT00018811
- Testing
- Relaxation training & thermal biofeedback, Surface EMG biofeedback
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Myeloproliferative Disorders, Kidney Cancer
Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation
RATIONALE: Light-emitting diode (LED) therapy may be able to prevent mucositis of the mouth. PURPOSE: Randomized phase II trial to determine the effectiveness of LED therapy in preventing mucositis of the mouth in children who…
- Conditions
- Chronic Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma
- Trial name
- NCT00036712
- Testing
- management of therapy complications, pain therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medical College of Wisconsin
Headache, Headache Disorders
Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire
The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Disability Questionnaire (HDQ).
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Headache, Tension
- Trial name
- NCT04736654
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Gazi University
Complex Regional Pain Syndromes
Graded Motor Imagery Effects on Body Perception Disturbance in Complex Regional Pain Syndrome : a Randomised Controlled Trial
Complex Regional Pain Syndrome (CRPS) is a debilitating pain condition that usually develops following trauma. Patients with CRPS experience intense, continuing, disproportionate pain and multiple symptoms such as changes or…
- Trial name
- Bath-Min (NCT07818174)
- Testing
- Graded Motor Imagery + Therapeutic exercises
- Where
- 20 sites in France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Chronic Pain
Effects of a Patient Driven Assessment Process With Complex Pain Patients
The objective of this study is to engage patients with chronic pain and other key stakeholders in an iterative process of pilot-testing a validated patient generated instrument, the Measure Yourself Medical Outcome Profile…
- Trial name
- PDAP (NCT02746354)
- Testing
- The MySupport tool
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kaiser Permanente
Pelvic Pain, Depression, Anxiety
Chronic Pelvic Pain and Education Skills Training for Women Veterans
Chronic pelvic pain (CPP) is a debilitating condition that disproportionately affects women Veterans (25% vs. 16% of civilian women).
- Trial name
- NCT05368155
- Testing
- Brief ACT for Pelvic Pain
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Baylor College of Medicine
Chronic Pain
Acceptance and Commitment Therapy for Chronic Pain in Integrated Primary Care
This mixed-methods pilot randomized controlled trial sought to: 1) evaluate implementation of a brief Acceptance and Commitment Therapy treatment for chronic pain delivered by an integrated behavioral health consultant in primary…
- Trial name
- NCT04978961
- Testing
- Focused Acceptance & Commitment Therapy (FACT), Enhanced Treatment as Usual (ETAU)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post COVID Condition, Chronic Pain
Effect of Non-Invasive Neuromodulation on Primary Chronic Pain, Including Post-COVID-19
The aim of this study is to analyse whether there is an advantage in adding low-intensity electrical stimulations to the vagus nerve with electrodes in the outer ear to control pain and fatigue in people with primary chronic…
- Conditions
- Post COVID Condition, Chronic Pain, Healthy
- Trial name
- NCT06689345
- Testing
- taVNS - transauricular vagal nerve stimulation, rPMS - repetitive peripheric magnetic stimulation, rTMS - repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Federal University of ABC
Opiate Replacement Therapy
The Effect of Primary Care Opioid Taper Plans on Sustained Opioid Taper
The objective of this study is to examine the effects of opioid taper plans as documented in the electronic medical record for Kaiser Permanente Washington (KPWA) patients.
- Trial name
- NCT03748862
- Testing
- Taper Plan
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Kaiser Permanente
Chronic Pain, Widespread
A Multi-disciplinary Pain Intervention (MUD-PI) for Patients With Chronic Widespread Primary Pain
Patients who fulfilled inclusion criteria and consented to participate received either treatment as usual at the clinic, or were enrolled in a group-therapy based intervention, the multi-disciplinary pain intervention, led by a…
- Trial name
- MUD-PI (NCT03413501)
- Testing
- MUD-PI
- Volunteers
- 49 people
- Sponsor
- Oslo University Hospital