Clinical trials: Chronic Primary Pain
Persistent Pain, Pain Management
Self-monitoring and Remote Monitoring of Chronic Pain in Primary Care - Using a Digital Tool to Improve Quality of Life
Chronic pain impacts individuals, their families, and society significantly, yet specialist care resources are limited, with most patients managed in primary care.
- Conditions
- Persistent Pain, Pain Management, Remote Monitoring
- Trial name
- NCT07141108
- Testing
- Paindrainer Care system
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University
Chronic Tension-Type Headache
Deep Neck Flexor Exercises Versus Myofascial Release of Suboccipital Muscles in Chronic Tension-type Headache
According to the study of the burden of diseases in 2018, tension-type headache(TTH) is the most common type of primary headache and ranks third in terms of prevalence among 328 diseases and injuries in 195 countries from 1990 to…
- Trial name
- NCT05383365
- Volunteers
- 44 people
- Sponsor
- Iran University of Medical Sciences
Migraine
Head Awareness in Chronic Migraine Patients
Research indicates that different beliefs about the nature of back problems and their future consequences direct behaviors that may cause falsely stimulated neuroplastic changes.
- Trial name
- Awareness (NCT06857383)
- Testing
- Fremantle Headache Awareness Questionnaire
- Where
- 13 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Bozok University
Migraine, Chronic Migraine, Headache
A Study Investigating the Efficacy of GON Blocks.
Greater occipital nerve block ("GON block") is carried out extensively in the treatment of chronic migraine, but more research is required to understand the effectiveness of the procedure.
- Trial name
- NCT04017741
- Testing
- Combined Depo-Medrone and Lidocaine, Sodium Chloride 0.9% Inj
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Barts & The London NHS Trust
Fibromyalgia, Fibromyalgia (FM)
The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients
The goal of this clinical trial is to learn if a traditional grape-based fermented drink called hardaliye helps treat fibromyalgia in adult women.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome, Primary
- Trial name
- NCT07403929
- Testing
- Medical Nutrition Therapy (MNT), Hardaliye (200 mL/day)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Migraine Disorders, Facial Pain Disorder, Cluster Headache, Trigeminal Neuralgia, Trigeminal Autonomic Cephalalgias
Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes
Purpose of the Study: This study aims to evaluate the clinical effectiveness and long-term outcomes of "Sphenopalatine Ganglion (SPG) Pulsed Radiofrequency (PRF)" treatment in patients with chronic headaches and facial pain.
- Trial name
- SPG-PRF (NCT07370142)
- Testing
- Pulsed Radiofrequency of the Sphenopalatine Ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara City Hospital Bilkent
Arthritis, Asthma
Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems
Behavioral problems are part of many of the chronic diseases that cause the majority of illness, disability and death. Tobacco, diet, physical inactivity, alcohol, drug abuse, failure to take treatment, sleep problems, anxiety…
- Conditions
- Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes
- Trial name
- IBHPC (NCT02868983)
- Testing
- Integration
- Where
- United States
- Volunteers
- 4,025 people
- Sponsor
- University of Vermont
Chronic Pain Syndrome, Chronic Pain
Supporting Self-management of Chronic Pain
Does the Navigator Tool Intervention improve communication regarding self-management during consultations between healthcare professionals and people with chronic pain? As there is usually no cure for chronic pain, healthcare…
- Conditions
- Chronic Pain Syndrome, Chronic Pain, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- NCT03119896
- Testing
- The Navigator Tool Intervention
- Where
- 5 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- Pain Concern
Subacute Nonspecific Low Back Pain, Chronic Nonspecific Low Back Pain
Effectiveness of Group GDS and Individual GDS for Treatment of Low Back Pain in Primary Care
A cluster, randomized, controlled clinical trial, where the hypothesis is that Group GDS and Individual GDS are effective in the treatment of nonspecific low back pain.
- Trial name
- NCT01060280
- Testing
- Education on active management, Group GDS physiotherapy, Individual GDS physiotherapy
- Where
- Spain
- Volunteers
- 461 people
- Sponsor
- Kovacs Foundation
Chronic Noncancer Pain
Integrating Patient Reported Outcomes (I-PRO) Study for Multidisciplinary Pain Care
The purpose of this study is to assess the impact of clinician education, electronic health record integrated patient reported outcomes, and electronic health record integrated decision support on pain-related care quality…
- Trial name
- I-PRO (NCT02188667)
- Testing
- Providers of Novel Care, Providers of Usual Care
- Where
- 4 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Florida
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Migraine, Migraine Disorders
Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study
This is a 128-week open-label study to assess the long-term safety and tolerabilty of the monoclonal antibody erenumab in migraine patients.
- Conditions
- Migraine, Migraine Disorders, Migraine Headache
- Trial name
- APOLLON (NCT04084314)
- Testing
- Erenumab
- Where
- 75 sites in Germany
- Volunteers
- 701 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Pain
Neuronavigated Repetitive Transcranial Magnetic Stimulation (nrTMS) of the Dorsolateral Prefrontal and Primary Motor Cortex for the Treatment of Chronic Pain
This study investigated the effects of navigated repetitive Transcranial Magnetic Stimulation on nociception and quality of life in patients suffering from chronic pain conditions.
- Trial name
- NCT04934150
- Testing
- navigated repetitive Transcranial Stimulation
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Medical University of Graz
Episodic Cluster Headache, Chronic Cluster Headache
A Study of LY2951742 (Galcanezumab) in Participants With Cluster Headache
The main purpose of this study is to assess the long-term safety and tolerability of galcanezumab administered up to once monthly in participants with episodic or chronic cluster headache who have completed study I5Q-MC-CGAL…
- Trial name
- NCT02797951
- Testing
- Galcanezumab
- Where
- 40 sites in United States, Belgium and 10 more
- Volunteers
- 165 people
- Sponsor
- Eli Lilly and Company
Low Back Pain, Neuralgia
Primary Care Identification Of Patients With Chronic Neuropathic Low Back Pain Study
A0081256 is a prospective, open-label, multi-centre European study designed to raise awareness and enhance the diagnosis of patients with chronic low back pain with a neuropathic pain component in primary care who are refractory…
- Trial name
- PINPOINT (NCT01298466)
- Testing
- Pregabalin
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Migraine, Headache
miR-155 Expression in Episodic and Chronic Migraine
Migraine is a common, yet often disabling, neurological disease that affects over 1 billion people around the world. It's the second most disabling disease globally and the leading cause of disability for people under the age of…
- Conditions
- Migraine, Headache, Pain, Chronic Migraine
- Trial name
- NCT05891808
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Hip Pain Chronic
Transmuscular Quadratus Lumborum Block Plus Pericapsular Injection vs Pericapsular Injection
The purpose of this research study is to compare two different treatment options on their effectiveness to reduce post-operative pain, narcotic (opioid pain medication) usage and recovery time in patients undergoing primary hip…
- Trial name
- NCT04353414
- Testing
- Transmuscular Quadratus Lumborum Block, Pericapsular injection, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- NYU Langone Health
Migraine
The Effectiveness and Safety of Topiramate on Prevention of Chronic Migraine
The purpose of this study is to evaluate the safety and effectiveness of individualized doses (50 to 200 milligrams) of topiramate tablets compared against placebo for the prevention of chronic migraine headaches over a period of…
- Trial name
- NCT00216606
- Testing
- topiramate
- Volunteers
- 59 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Chronic Pain
Chronic Pain OneSheet Clinical Trial
The purpose of the study is to determine whether and how having access to the Chronic Pain OneSheet clinical decision support tool in Epic affects the ordering, prescribing, goal-setting, risk monitoring, and outcome measuring…
- Trial name
- NCT04295135
- Testing
- Chronic Pain OneSheet
- Where
- 2 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Indiana University