Clinical trials: Chronic Primary Pain, open to volunteers
Fibromyalgia, Fibromyalgia (FM)
The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients
The goal of this clinical trial is to learn if a traditional grape-based fermented drink called hardaliye helps treat fibromyalgia in adult women.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome, Primary
- Trial name
- NCT07403929
- Testing
- Medical Nutrition Therapy (MNT), Hardaliye (200 mL/day)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Myalgia, Muscle Pain
Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with…
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT06405646
- Testing
- Blood CB1, CB2, TRPV-1 concentration measurement
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Complex Regional Pain Syndromes
Graded Motor Imagery Effects on Body Perception Disturbance in Complex Regional Pain Syndrome : a Randomised Controlled Trial
Complex Regional Pain Syndrome (CRPS) is a debilitating pain condition that usually develops following trauma. Patients with CRPS experience intense, continuing, disproportionate pain and multiple symptoms such as changes or…
- Trial name
- Bath-Min (NCT07818174)
- Testing
- Graded Motor Imagery + Therapeutic exercises
- Where
- 20 sites in France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Chronic Nausea, Anxiety
AROMA-NT: Essential Oils and Wearable TENS Device for Chronic Nausea
This study will investigate how two inhaled essential oil products (QueaseEASE and STILL) and a wearable transcutaneous electrical nerve stimulation (TENS) device (ReliefBand) affect chronic nausea and anxiety in adults with…
- Trial name
- AROMA-NT (NCT07720336)
- Testing
- Inhaled Essential Oils, Wearable TENS Device
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Ohio State University
Migraine Disorder, Low Back Pain
Sleep Hygiene Education to Improve Sleep in Chronic Migraine and Back Pain
The goal of this clinical trial is to learn whether sleep hygiene education can improve sleep quality and reduce pain in adults with migraine and/or chronic lower back pain.
- Conditions
- Migraine Disorder, Low Back Pain, Chronic Pain, Sleep Disorder (Disorder)
- Trial name
- NCT07425964
- Testing
- Sleep Hygiene Education
- Volunteers
- 100 people
- Sponsor
- Aalborg University
Depression, Anxiety
Evaluation of the PACE/PACENET BHL Clinical Program
The SUpporting Seniors Receiving Treatment And INtervention (SUSTAIN) program is a telephone-based clinical service designed to help identify and manage behavioral health issues among PACE/PACENET enrollees.
- Conditions
- Depression, Anxiety, Pain, Chronic
- Trial name
- SUSTAINIV (NCT02463266)
- Testing
- SUSTAIN Monitoring and Care Management
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- University of Pennsylvania
Head and Neck Cancer, Locally Advanced Head and Neck Carcinoma
Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer
This is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergoing chemoradiation.
- Trial name
- NCT05156060
- Testing
- Gabapentin, Ketamine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Natalie Lockney
Migraine, Episodic Migraine
Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine
The goal of this observational study is to evaluate clinical differences in patients who received preventive treatment with medication targeting calcitonin gene-related peptide (CGRP) or its receptor: monoclonal antibodies…
- Conditions
- Migraine, Episodic Migraine, Chronic Migraine, Headache
- Trial name
- EUREkA (NCT07159750)
- Testing
- CGRP antibody or gepant
- Where
- 26 sites in United States, Argentina and 11 more
- Volunteers
- 700 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Social Skills, Primary Care
Social Skills in Chronic Pain, Addiction, Intimate Partner Violence and Primary Care
Context: psychosocial competencies (CPS) are higher cognitive functions defined by the ability to interact with others by adopting appropriate and positive behavior.
- Trial name
- Skills-PAVIP (NCT07145528)
- Testing
- Questionary with a case-report-form
- Where
- France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Migraine
Migraine is Associated With Altered Mechanical Pain Sensitivity. This Study Investigates Mechanical Pain Sensitivity, Headache Burden, and Quality of Life in Episodic and Chronic Migraine, Comparing Pressure Algometry and Algopeg® and Assessing Mechanosensitivity of Peripheral Nerves.
Migraine is one of the most prevalent neurological disorders and is associated with a substantial individual and societal burden.
- Trial name
- MechSens_Migra (NCT07559565)
- Testing
- pressure pain algometry
- Where
- Austria
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bernhard Taxer
Shoulder Pain
Effectiveness of Action Observation and Motor Imagery Intervention Plus Exercise for Chronic Painful Shoulder in Primary Care
Objective: to evaluate the effectiveness of an action observation program (OA) and motor imagery (MI) -integrated into routine physiotherapy practice- to reduce disability associated with chronic shoulder pain in primary care…
- Trial name
- OPTIMIST (NCT04118439)
- Testing
- Motor Imaginery and Action Observation
- Volunteers
- 100 people
- Sponsor
- Universidad Autonoma de Madrid
Chronic Migraine, Chronic Migraine, Headache
Efficacy of Nerve Block Versus Botox in Chronic Migraine Management
The goal of this clinical trial is to determine whether nerve block injections (specifically, supratrochlear and greater occipital nerve injections) are as effective as Botulinum toxin A (Botox) injections in treating chronic…
- Trial name
- NCT06684249
- Testing
- Nerve Block Injections, Botulinum Toxin A
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Zagazig University
Chronic Daily Headache, Chronic Migraine
Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics
Study is aimed at determining why some patients with episodic headache proceed to chronic daily or near daily headaches. The Investigators seek to discover differences in brain anatomy and function, composition of cerebrospinal…
- Trial name
- NCT03231241
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Stanford University
Chronic Pain, Migraine
Evaluation of a Mind-Body Based Approach for Chronic Pain Treatment
The investigators are evaluating the effects of a mind-body mobile application, in combination with a guided movement program, on the experience of chronic pain.
- Conditions
- Chronic Pain, Migraine, Chronic Pain Syndrome
- Trial name
- NCT07143396
- Testing
- Mind-body mobile application and guided movement
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of the Fraser Valley
Chronic Migraine, Adverse Childhood Experiences
Effects of Online Mindfulness Therapy on Pain and Stress in Adults With Chronic Migraine and Adverse Childhood Experiences
This study aims to evaluate the effectiveness of an online Mindfulness-Based Cognitive Therapy (MBCT) program in reducing pain, stress-related symptoms, and improving functionality in adults with chronic migraine and a history of…
- Conditions
- Chronic Migraine, Adverse Childhood Experiences, Depression, Anxiety
- Trial name
- NCT07033520
- Testing
- Online Mindfulness-Based Cognitive Therapy
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Fundación Cardiovascular de Colombia
Migraine, Headache
Determining the Utility of a Behavioral Intervention in Chronic Migraine
This proposal will involve a pilot study to evaluate the feasibility, acceptability, and outcomes of a lifestyle behavior protocol in managing chronic migraine.
- Conditions
- Migraine, Headache, Migraine Disorders, Chronic Migraine
- Trial name
- RLB (NCT05415020)
- Testing
- Lifestyle Behavior Protocol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Chronic Pain
Group-based Integrative Pain Management in Primary Care Safety Net Clinics
Socioeconomically disadvantaged populations have a high prevalence of chronic pain, exacerbated by social isolation, intersectional stigma, and disparities in pain assessment and treatment options.
- Trial name
- IPMP+ (NCT06327542)
- Testing
- Group Acupuncture, Integrative Group Medical Visits
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of California, San Francisco
Chronic Pain
Integrating Nonpharmacologic Strategies for Pain With Inclusion, Respect, and Equity
INSPIRE creates a trilingual mobile app and telehealth coaching program to promote non-pharmacologic strategies for pain management with Black, Chinese, and Latinx communities in the San Francisco Bay Area.
- Trial name
- INSPIRE (NCT06183281)
- Testing
- CBT, Mindfulness, and Movement
- Where
- 2 sites in United States
- Volunteers
- 586 people
- Sponsor
- University of California, San Francisco
Chronic Pain (Back / Neck)
Effectiveness of a Pain Neuroscience Education and Therapeutic Exercise Program Delivered by Primary Care Physiotherapists to Patients With Chronic Nociplastic Spinal Pain
The main objective of the project is to evaluate the effectiveness, in terms of quality of life, of a therapy based on an Active Coping Protocol for Non-Cancer Chronic Pain in the Primary Care setting.
- Trial name
- AP-AADC (NCT07133607)
- Testing
- education about pain and physical excersice, education about pain and physical excersice with somatosensorial treatment, Classic physiotherapy treatment with physical exercise, analgesic electrotherapy and thermotherapy
- Volunteers
- 135 people
- Sponsor
- Distrito de Atención Primaria Sevilla