Clinical trials: Chronic Pulmonary Disease
Pulmonary Vascular Disease, Pulmonary Arterial Hypertension
High Altitude (HA) Residents With Pulmonary Vascular Diseseases (PVD), Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) vs Sea Level (LA)
To study the effect of relocation from 2840m (Quito) to sea level (Pedernales) in patients with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension (PH)…
- Conditions
- Pulmonary Vascular Disease, Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT06092424
- Testing
- Relocation from HA to LA
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Neuromuscular Electrical Stimulation as an Adjunct to Exercise Training in Stable Chronic Obstructive Pulmonary Disease (COPD)
Skeletal muscle dysfunction impairs exercise capacity, quality of life and prognosis in chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01658046
- Testing
- Neuromuscular electrical stimulation, Endurance training, Quadriceps strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Hacettepe University
Emphysema, Chronic Obstructive Pulmonary Disease (COPD)
Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability
The purpose of this research study is to perfect the technique of EVLP and learn about the safety of transplanting lungs that have been ventilated (attached to a breathing machine or ventilator to deliver oxygen) and perfused…
- Conditions
- Emphysema, Chronic Obstructive Pulmonary Disease (COPD), Cystic Fibrosis, Pulmonary Fibrosis
- Trial name
- NCT01241942
- Testing
- Steen Solution™, Conventional Lung Transplant
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of North Carolina, Chapel Hill
COPD, Kinesiophobia Due to Dyspnea
Clinical Variables and Dyspnea and Fear of Movement in Chronic Obstructive Pulmonary Patients
Patients diagnosed with COPD who applied to the Pulmonary Diseases Department of Kırıkkale Yüksek İhtisas Hospital will be included in the study.
- Trial name
- NCT06442059
- Testing
- Kinesiophobia Level Due to Dyspnea
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Kırıkkale University
Community Health Nursing Education, Chronic Obstructive Pulmonary Disease
Virtual Reality Cave vs. Simulated Home for Community Nursing Education: A Crossover Trial Comparing Student Competence, Confidence, and Satisfaction
Background and Purpose Community health nursing is essential for providing healthcare to individuals in home and neighborhood settings.
- Conditions
- Community Health Nursing Education, Chronic Obstructive Pulmonary Disease, Pulmonary Tuberculosis
- Trial name
- NCT07595588
- Testing
- VR CAVE Immersive Simulation for Community Health Nursing Education, Traditional Simulated Home Environment for Community Health Nursing Training
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Chronic Obstructive Pulmonary Disease (COPD)
Effects of a 4-week Acu-Transcutaneous Electrical Nerve Stimulation (Acu-TENS) Program on Subjects With Stable Chronic Obstructive Pulmonary Disease (COPD)
The objectives of this study are to investigate the effectiveness of Acu-TENS (transcutaneous electrical nerve stimulation applied on acupoints) on lung functions and quality of life and to explore the associated underlying…
- Trial name
- NCT00971490
- Testing
- Acu-TENS (Transcutaneous electrical nerve stimulation)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Obstructive Pulmonary Diseases
Comparing Online Pulmonary Rehabilitation 'myPR' Versus Conventional Pulmonary Rehabilitation for Patients With COPD
Over time, patients with COPD (Chronic Obstructive Pulmonary Disease) develop progressive symptoms of breathlessness, which can limit day-to-day activities and tolerance to exercise.
- Trial name
- TROOPeR (NCT02706613)
- Testing
- Face to Face Pulmonary Rehabilitaton, Online Pulmonary Rehab
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- my mhealth Ltd
Pulmonary Disease, Chronic Obstructive
A Study in the US Based on Pharmacy and Medical Claims That Compares How Well Stiolto® and Trelegy® Work in People With Chronic Obstructive Pulmonary Disease (COPD)
This study looks at data from people with chronic obstructive pulmonary disease (COPD). Some used Stiolto Respimat and the others Trelegy Ellipta as their first treatment for COPD.
- Trial name
- NCT05169424
- Testing
- Trelegy Ellipta, Stiolto Respimat, Tiotropium + Olodaterol (5/5 mcg)
- Where
- United States
- Volunteers
- 9,117 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Walking Program With Pedometer on Quality of Life in COPD
The aim of this study is to investigate the effects of a walking program on exercise capacity and quality of life in patient with COPD.
- Trial name
- COPD (NCT05251623)
- Testing
- walking program
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Chang Gung University
Asthma, COPD
Comprehension and Evaluation of a Pictorial Action Plan for Those With Asthma or COPD
Some five million people in the United Kingdom (U.K.) have asthma. The British Guidelines on Asthma recommend self management education and the issuing of written personal asthma action plans.
- Trial name
- NCT00129662
- Testing
- Pictorial action plan
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Imperial College London
COPD, Asthma
Writing About Disease: Effect on Rehabilitation?
Therapeutic writing about one's emotions has been described previously (J Pennebaker: Emotions, disclosure and health. Am Psychol. Assoc 1995).
- Trial name
- NCT00251420
- Testing
- writing about disease
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- LHL Helse
Asthma, COPD (Chronic Obstructive Pulmonary Disease)
Reducing Exposure With Air Cleaners and Technology
Fine particulate matter (PM2.5) is a type of air pollution made up of extremely tiny particles that can harm our health. Because PM2.5 particles are so small, they can travel deep into the lungs when we breathe.
- Trial name
- REACT (NCT07914010)
- Testing
- Air Cleaner, PM2.5 Monitor with Visual Air Quality Indicator, Educational Materials
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of California, Berkeley
COPD
Helmet Ventilation During Self-Paced Walking Test
The aim of this study is to investigate the use helmet ventilation (HV) in walking test and analysis of effect patients with COPD.
- Trial name
- NCT04156724
- Testing
- Helmet vetilation
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Fu Jen Catholic University
Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma
First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ Malignancies
NVG-111 is a bispecific antibody drug, having two "arms", one arm attaches to a substance on cancer cells called ROR1, the other arm attaches to the body's immune cells directing them to kill the cancer cells.
- Conditions
- Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma
- Trial name
- NCT04763083
- Testing
- NVG-111
- Where
- 3 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- NovalGen Ltd.
COPD
The Effects of Oscillatory Positive Expiratory Pressure (OPEP) Therapy in Patients With COPD
The goal of this non-pharmacologic interventional study is to learn if Oscillatory Positive Expiratory Pressure (OPEP) therapy can improve disease impact and respiratory system dynamics in patients with COPD.
- Trial name
- NCT06614959
- Testing
- Oscillatory Positive Expiratory Pressure (OPEP) Therapy
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Obstructive Pulmonary Disease
Inclined Versus Standard Exercise for COPD Patients
This study is designed to provide information regarding how to improve pulmonary rehabilitation for persons with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT06749262
- Testing
- walking on incline or walking at increasing speed for 36 visits
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Heart Diseases, Heart Valve Diseases
Acute Kidney Injury After Cardiac Surgery
The study aims to identify the Following: - 1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes). 2.
- Conditions
- Heart Diseases, Heart Valve Diseases, Heart Shock, Cardiac Disease
- Trial name
- NCT05079724
- Testing
- Cardiac Surgery
- Volunteers
- 200 people
- Sponsor
- Assiut University
Chronic Liver Disease, Thyroid Disease
The Development of Quantitative Ultrasound Imaging Software Platform
The goal of this observational study is to compare the image differences between conventional ultrasound and artificial intelligence-based ultrasound software in conscious adults.
- Conditions
- Chronic Liver Disease, Thyroid Disease, Benign Breast Disease, Malignant Breast Neoplasm
- Trial name
- NCT05836246
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Seoul National University Bundang Hospital
Pulmonary Disease, Chronic Obstructive
Severe Chronic Obstructive Pulmonary Disease Inhalation Profiles Comparison
This purpose of this study is to obtain inhalation profiles in subjects with very severe Chronic Obstructive Pulmonary Disease (COPD). This is a study with no investigational medicinal product.
- Trial name
- NCT02076269
- Testing
- No Intervention
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- GlaxoSmithKline
Chronic Respiratory Failure, Cardiac Disease, Pulmonary Disease
Advanced Respiratory Monitoring and Oxygen Therapy in Chronically Ill Patients With Acute Respiratory Failure
This study is testing whether a new type of home oxygen therapy, called high-flow nasal cannula (HFNC), can improve breathing comfort and quality of life for people with long-term lung or heart conditions who need oxygen after…
- Conditions
- Chronic Respiratory Failure, Cardiac Disease, Pulmonary Disease, Acute Respiratory Failure (ARF)
- Trial name
- HOME- Oxygen (NCT07157696)
- Testing
- High-Flow Nasal Cannula (HFNC) Oxygen Therapy, Oxygen therapy
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Università degli Studi di Ferrara
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