Clinical trials: Chronic Pulmonary Obstruction
Chronic Obstructive Pulmonary Disease, Chronic Bronchitis
Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes
The purpose of this study is to compare the effects of e-cigarettes and continued smoking on pulmonary and cardiac outcomes in a population with established pulmonary disease.
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema, Asthma-COPD Overlap Syndrome
- Trial name
- NCT05610514
- Testing
- E-Cigarette, Financial Incentives
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Vermont
Chronic Obstructive Pulmonary Disease, Balance
Investigation of Impairments in Body Functions and Structures, Activities and Participation Restrictions in COPD
This cross-sectional study aims to investigate to the impairments in body functions and structures, activities and participation restrictions according to the International Classification of Functioning, Disability and Health…
- Conditions
- Chronic Obstructive Pulmonary Disease, Balance, Activity, Motor, Participation, Patient
- Trial name
- NCT05632120
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Obstructive Pulmonary Disease
Oxis 9mcg Turbuhaler Clinical Experience Investigation
The purpose of the investigation is to confirm the ADR development and the contributing factors possibly having an impact on the safety under the post-marketing actual use of Oxis 9 mcg Turbuhaler.
- Trial name
- NCT01749462
- Where
- 41 sites in Japan
- Volunteers
- 398 people
- Sponsor
- AstraZeneca
COPD
Efficacy of AZD3199 in Chronic Obstructive Pulmonary Disease (COPD) Patients
The purpose of this study is to investigate the efficacy, safety and tolerability of 4 weeks treatment with AZD3199 in moderate to severe COPD.
- Trial name
- GLAD (NCT00929708)
- Testing
- AZD3199, formoterol
- Where
- 38 sites in Bulgaria, Canada and 3 more
- Volunteers
- 329 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Home Rehabilitation Via Telemonitoring in Patients With COPD
COPD is the fourth leading cause of death in the world and is the only one of the top five illnesses whose death rate is still increasing. It is mainly caused by smoking.
- Trial name
- TELECARE (NCT02618746)
- Testing
- Telerehabilitation, Hospital based Rehabilitation
- Volunteers
- 150 people
- Sponsor
- Thorax Research Foundation
Chronic Obstructive Pulmonary Disease
Pulmonary Microbiota in Patients With Chronic Obstructive Pulmonary Disease Colonized With P. Aeruginosa Resistant to Imipenem
Pseudomonas aeruginosa (PA ) is associated with chronic lung infections in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- MiPAD (NCT03008746)
- Testing
- water used for oral wash, sputum, oral wash
- Where
- France
- Volunteers
- 58 people
- Sponsor
- CHU de Reims
Hypoxemia, Gastric Cancer (Diagnosis)
High-Flow Nasal Cannula Oxygenation During Sedated Gastrointestinal Endoscopy in Patients With Chronic Obstructive Pulmonary Disease
Hypoxemia is the most common adverse event during propofol sedation for gastrointestinal endoscopy in patients with chronic obstructive pulmonary disease (COPD) due to diminished pulmonary reserve.
- Conditions
- Hypoxemia, Gastric Cancer (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD), Esophageal Cancer
- Trial name
- NCT07791979
- Testing
- High-flow nasal cannula
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhejiang University
Joint Osteoarthritis, Atherosclerosis of the Distal Arteries, Without Gangrene
Evaluation of Impaired Mobility in Chronic Illness Constitution of a Cohort
Chronic illness is a public health issue and mobility loss is frequent in this population. Among its' multiple physical and psychological consequences, increased mortality and cardiovascular morbidity seem the main concern.
- Conditions
- Joint Osteoarthritis, Atherosclerosis of the Distal Arteries, Without Gangrene, Parkinson Disease, Chronic Obstructive Pulmonary Disease, Unspecified
- Trial name
- EVALMOB (NCT04375280)
- Testing
- Development of a screening algorithm designed to determine a "dysmobility" profile in patients with chronic illness.
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pulmonary Disease, Chronic Obstructive
General Practice Quality Assurance Project. Chronic Obstructive Pulmonary Disease (COPD) Diagnosis and Treatment
A Cross sectional observational Quality Assurance Project in General Practice to COPD Diagnosis and Treatment
- Trial name
- NCT00319813
- Testing
- Education
- Volunteers
- 8,000 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Nutritional Risk and Diaphragmatic Thickness in Mechanically Ventilated COPD Patients
Malnutrition and muscle wasting are frequent complications in patients with chronic obstructive pulmonary disease (COPD) experiencing acute exacerbations.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Malnutrition, Respiratory Failure
- Trial name
- NCT07788170
- Volunteers
- 120 people
- Sponsor
- Assiut University
Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
Longitudinal Study of Cortisol and Pulmonary Function
To conduct a longitudinal study of the relationship between the rate of decline of pulmonary function and measurements of cortisol concentration and excretion in a sample of middle-aged and older men and their wives.
- Trial name
- NCT00005370
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Obstructive Pulmonary Disease
Change of Inspiratory Peak Flow in COPD
Chronic obstructive bronchitis and emphysema (COPD) are pathophysiologically characterized by inflammatory and structural changes in the lung.
- Trial name
- NCT00561886
- Testing
- Formoterol
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johannes Gutenberg University Mainz
Pulmonary Disease, Chronic Obstructive
(In)Voluntary Assessed Quadriceps Muscle Endurance in COPD
The primary objective is to assess the relation between involuntary and voluntary assessed quadriceps muscle endurance in patients with COPD. We hypothesized a good correlation (>0.8) between the measurements.
- Trial name
- Bionic (NCT05427773)
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Radboud University Medical Center
Dacryocystitis, Dacryocystitis; Chronic
Examination of Lacrimal Sac and Nasal Mucosa Preparations Taken in Dacryocystorhinostomy Surgery of Patients With Nasolacrimal Duct Obstruction and Comparison of Clinical Groups With Each Other
The goal of this observational study is to investigate etiology and pathogenesis of nasolacrimal duct obstruction and dacryocystitis in different adult clinic groups.
- Conditions
- Dacryocystitis, Dacryocystitis; Chronic, Dacryocystorhinostomy, Epiphora
- Trial name
- NCT06810089
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Uludag University
Chronic Obstructive Pulmonary Disease
Effects on PaCO2 Levels of Two Different Nasal Cannula in COPD Patients
High-flow nasal cannula (HFNC) therapy is increasingly used in the management of acute respiratory failure. Its clinical application has been expanded also in other specific settings In stable COPD patients and in those…
- Trial name
- CODUET (NCT05528289)
- Testing
- AIRVO 2, with conventional symmetric nasal cannula, AIRVO 2, the new asymmetric nasal cannula
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Chronic Obstructive Pulmonary Disease (COPD)
Long Term Safety Study of NVA237 vs QAB149 in COPD Patients
The purpose of the study is to provide long term safety data of NVA237. This study will assess the safety and tolerability of a single dose strength of NVA237.
- Trial name
- NCT01697696
- Testing
- NVA237, Long-acting beta 2-agonist (LABA)
- Where
- 61 sites in United States
- Volunteers
- 511 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease (COPD)
Short-Term Inspiratory Muscle Training and Aerobic Exercise in Women With COPD
Brief Summary: This randomized controlled trial evaluated the short-term effects of inspiratory muscle training, aerobic exercise, combined inspiratory muscle training and aerobic exercise, placebo inspiratory muscle training…
- Trial name
- IMT-COPD (NCT07604961)
- Testing
- Inspiratory Muscle Training, Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Mehmet İsmail TOSUN
Chronic Obstructive Pulmonary Disease
Balance Training for Chronic Obstructive Pulmonary Disease (COPD)
The study will involve direct knowledge translation of a laboratory-based study of balance training for patients with COPD, first to the investigators PR program and then, after disseminating the results, this approach could be…
- Trial name
- NCT02080442
- Testing
- Balance training
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Samantha Harrison
Emphysema, Lung Diseases
Emphysema: Physiologic Effects of Nutritional Support
To determine if enteral nutrition support (ENS) restores normal body weight and improves muscle strength, exercise performance, sensation of dyspnea, and quality of life in malnourished patients with chronic obstructive pulmonary…
- Conditions
- Emphysema, Lung Diseases, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00000573
- Testing
- enteral nutrition
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Obstructive Pulmonary Disease
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive)…
- Trial name
- THESEUS (NCT07190222)
- Testing
- Lunsekimig
- Where
- 314 sites in United States, Argentina and 24 more
- Volunteers
- 942 people
- Sponsor
- Sanofi
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