Clinical trials: Chronic Pulmonary Obstruction
Chronic Respiratory Disease, Chronic Pulmonary Aspergillosis
Pharmacological Evaluation of Antifungal in Chronic Pulmonary Aspergillosis
At present, pulmonary diffusion and target antifungal concentrations for APC in patients with sarcoidosis or chronic obstructive pulmonary disease (COPD) are unknown.
- Trial name
- EPAR-APC (NCT05064605)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Disease, Chronic Obstructive
Fluticasone Propionate/Salmeterol Combination 250/50 DISKUS in the Exercise Endurance Time in Patients With Chronic Obstructive Pulmonary Disease
The objective of this study is to demonstrate that, when added to tiotropium (TIO), fluticasone propionate/salmeterol combination (FSC) DISKUS 250/50 significantly increases exercise endurance time (EET) in the endurance shuttle…
- Trial name
- ESWT (NCT01124422)
- Testing
- fluticasone propionate/salmeterol inhalation powder DISKUS 250/50, tiotropium bromide inhalation powder HandiHaler
- Where
- 27 sites in United States, Canada
- Volunteers
- 255 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmoriary Disease (COPD), Asthma
Clinical Study on the Treatment of Chronic Airway Diseases (Asthma, Chronic Obstructive Pulmonary Disease) with Shu Fei Tie
Conduct a multi-center, large-sample, randomized controlled clinical study of "winter disease being cared in summer" with Shu Fei Tie prevent recurrence of Asthma and COPD, scientifically evaluate the clinical efficacy and safety…
- Trial name
- NCT06691802
- Testing
- Shu Fei Tie
- Where
- China
- Volunteers
- 2,312 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Chronic Obstructive Pulmonary Disease
CareCOPD - COPD Home Monitoring Study
This is a pilot study to demonstrate early validation of objective home-monitoring of Chronic obstructive pulmonary disease (COPD) patients by combining accurate and relevant patient data of medication and lung function (lung…
- Trial name
- NCT04918095
- Testing
- CareCOPD Platform
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cognita Labs LLC
Lung Diseases, Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Gene Localization
To localize within the genome a chronic obstructive pulmonary disease susceptibility gene.
- Trial name
- NCT00037739
- Sponsor
- University of Utah
Acute Myocardial Infraction or Chest Pain, Chronic Obstructive Pulmonary Disease (COPD)
Developing Enhanced Prediction Models
In this study, patients will be prospectively enrolled for data collection to design prediction models that integrate claims data (inpatient, outpatient, and pharmacy), electronic health record data (on clinical, social, and…
- Conditions
- Acute Myocardial Infraction or Chest Pain, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF), Diabetes
- Trial name
- PREDICT (NCT02983812)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Pennsylvania
Chronic Obstructive Pulmonary Disease
A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of TQC3302 Inhalation Spray in Healthy Adult Subjects
Groups 1, 3, 4, 5 and 6 of this research team adopted a single-center, open-label design. Group 2 used a three-sequence, three-period crossover design, where participants in this dose group were randomly assigned to the three…
- Trial name
- NCT07267130
- Testing
- TQC3302 inhalation spray, TQC3302 inhalation spray+Tiotropium bromide and olodaterol hydrochloride inhalation spray +Budesonide Powder for Inhalation, Tiotropium bromide and olodaterol hydrochloride inhalation spray +Budesonide Powder for Inhalation+ TQC3302 inhalation spray
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical (Guangzhou) Co., Ltd.
Hypertension, Diabetes Mellitus, Type 2
Enhancing Community Health Through Patient Navigation, Advocacy and Social Support
Some patients who have multiple long-term health conditions have significant challenges accessing needed services despite available primary care and social services resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- ENCOMPASS (NCT03077386)
- Testing
- ENCOMPASS Intervention
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- University of Calgary
COPD
Acetylic Salicylic Acid for the Treatment of Chronic Obstructive Pulmonary Disease
The pathomechanisms of COPD are still not fully understood, and up to now there is no satisfying causal treatment inhibiting the progress of the disease. Available therapy is in most cases symptomatic.
- Trial name
- ASA-COPD (NCT01328145)
- Testing
- Acetylsalicylic acid
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- Medical University of Vienna
Osteoporosis, Obstructive Lung Disease
Breathing and Bones Initiative
This project will examine the current diagnosis and treatment of bone health in patients with obstructive airway disease. Patients will be referred to The Osteoporosis Centre of BC (OCBC) by their respirologist to be assessed for…
- Trial name
- NCT01161680
- Where
- 3 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Asthma, Chronic Obstructive Pulmonary Disease
Effectiveness of Influenza Vaccine Reminder Systems
Influenza disease causes significant morbidity and mortality in the Unites States each year. Although influenza can cause morbidity in otherwise healthy individuals, adults with chronic lung disease have significantly increased…
- Trial name
- NCT01852656
- Testing
- Postcard and IVR Reminder Group, Postcard Only Reminder Group, IVR Only Reminder Group
- Where
- United States
- Volunteers
- 12,255 people
- Sponsor
- Kaiser Permanente
Chronic Obstructive Pulmonary Disease (COPD
Study in Healthy Volunteers and COPD Patients to Evaluate the Efficacy and Safety of Inhaled TV46017
The primary objective of the study is to characterize the safety profile and duration of bronchodilation of a single dose of inhaled TV46017
- Trial name
- NCT02315131
- Testing
- TV46017
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Obstructive Pulmonary Disease (COPD
Identifying Early Chronic Obstructive Pulmonary Disease (COPD) Using Health Administrative Data
Chronic Obstructive Pulmonary Disease (COPD) affects the airways that causes shortness of breath, cough. COPD gets worse over time, and often leads to emergency department visits, hospital visits, frequent doctor appointments and…
- Trial name
- NCT04966637
- Testing
- COPD cohort
- Where
- Canada
- Volunteers
- 54,028 people
- Sponsor
- University of Alberta
COPD Chronic Obstructive Pulmonary Disease
Effectiveness of TNI vs. BiPAP in Chronic Global Insufficiency in COPD Patients
The purpose of this trial ist to investigate the difference of the efficacy of two systems for breath support in patients with COPD.
- Trial name
- TIBICO (NCT02007772)
- Testing
- nHF, BiPAP
- Where
- 14 sites in Germany
- Volunteers
- 105 people
- Sponsor
- University of Leipzig
Respiratory Function Tests, Chronic Obstructive Pulmonary Disease
Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease
Studies have shown that intravenous infusion and nebulized dexmedetomidine can improve lung function in mechanically ventilated patients, including those with preoperative COPD, exerting lung protection.
- Conditions
- Respiratory Function Tests, Chronic Obstructive Pulmonary Disease, Dexmedetomidine
- Trial name
- NCT06207331
- Testing
- Dexmedetomidine 0.5 μg/kg, Dexmedetomidine 1 μg/kg, Saline
- Where
- China
- Volunteers
- 6 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Chronic Obstructive Pulmonary Disease, Lung Diseases
Supplemental Selenium and Vitamin E and Pulmonary Function
To test whether supplementation with selenium and/or vitamin E affects pulmonary function.
- Conditions
- Chronic Obstructive Pulmonary Disease, Lung Diseases, Lung Diseases, Obstructive
- Trial name
- NCT00063453
- Testing
- Vitamin E, Selenium
- Volunteers
- 2,920 people, healthy volunteers welcome
- Sponsor
- Cornell University
Pulmonary Disease, Chronic Obstructive
Spot Marching Exercise Test in Chronic Obstructive Pulmonary Disease
the aim of this study to assess the relationship and compare physiological response between spot marching exercise test and 6 minute walk test in patient with chronic obstructive pulmonary disease
- Trial name
- SMT (NCT02719457)
- Testing
- 6 minute walk test (6 MWT), Spot marching test (SMT)
- Where
- 2 sites in Thailand
- Volunteers
- 30 people
- Sponsor
- Khon Kaen University
Chronic Obstructive Pulmonary Disease, Chronic Cough
Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic
The purpose of the study is to investigate the addition of high frequency chest wall oscillation (HFCWO) therapy to the prescribed care regimen to support the diaphragm during airway clearance among post-COVID patients with COPD…
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Cough, Covid19
- Trial name
- NCT04654481
- Testing
- HCFWO, Standard Care Plus Monitoring
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Obstructive Pulmonary Disease(COPD)
Effects of Inspiratory and Expiratory Pressure Training Methods in Patients With Chronic Obstructive Pulmonary Disease
The study will investigate the effects of different training types ,including combined inspiratory with expiratory pressure threshold training,inspiratory pressure threshold training on patients with chronic obstructive airway…
- Trial name
- NCT02326181
- Testing
- inspiratory pressure training group, mixed training group
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhujiang Hospital
Chronic Obstructive Pulmonary Disease
Comparison of Efficacy of Indacaterol Versus Placebo Over 12 Weeks
This 12-week study evaluated the efficacy and safety of indacaterol versus placebo.
- Trial name
- NCT01068600
- Testing
- Indacaterol
- Where
- 54 sites in United States
- Volunteers
- 318 people
- Sponsor
- Novartis
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