Clinical trials: Chronic Radiation Proctitis
Chronic Radiation Proctitis
Thalidomide in the Treatment of Chronic Radiation Proctitis With Intractable Bleeding
Chronic radiation proctitis (CRP) is the main secondary toxic injury after pelvic radiotherapy. Hematochezia is the most common symptom for more than 80% of CRP patients.
- Trial name
- Thal-CRP (NCT04680195)
- Testing
- Thalidomide
- Volunteers
- 62 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Radiation Injuries, Telangiectasis
Comparison Between Two Different Parameters of Argon Plasma Coagulation in the Treatment of Chronic Radiation Proctitis: Historical Control Trial.
There is a wide variability of options for treatment of chronic radiation proctitis. However, studies are still limited, usually case reports from a single center and few are comparative studies between methods.
- Conditions
- Radiation Injuries, Telangiectasis, Rectal Bleeding
- Trial name
- NCT02104271
- Testing
- Argon Plasma Coagulation, Historical control
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- Barretos Cancer Hospital
Chronic Radiation Proctitis
Umbilical-Cord-Derived Mesenchymal Stem Cells Injection for Chronic Radiation Proctitis
A Phase I/II study to evaluate the safety and preliminary efficacy of human umbilical cord-derived mesenchymal stem cell injection for the treatment of chronic radiation proctitis.
- Trial name
- NCT06438809
- Testing
- Mesenchymal Stem Cells (MSCs)
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
Chronic Radiation-induced Proctitis
KANGFUPEN Liquid Dressing for Chronic Radiation-Induced Rectal Injury
This clinical trial aims to evaluate the efficacy and safety of Kangfupen (a topical liquid dressing) in treating chronic radiation-induced proctitis (RTOG Grade 2 or higher). The key questions we aim to answer are: 1.
- Trial name
- NCT07065175
- Testing
- Kangfupen (liquid dressing) retention enema administration
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Peking Union Medical College Hospital
Chronic Radiation Proctitis
Jianzhong Qushi in Chronic RRI
This study is a multicenter, randomized, double-blind, placebo-controlled trial. Patients diagnosed as CRP and without TCM history will be enrolled and randomly assigned to either the treatment group (receiving standard care plus…
- Trial name
- ACRON (NCT06837597)
- Testing
- Jianzhong Qushi Formula
- Volunteers
- 168 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Chronic Radiation Proctitis, Rectal Bleeding
Transverse Colostomy for Refractory Hemorrhagic Chronic Radiation Proctitis: a Prospective Cohort Study
Refractory rectal bleeding of chronic radiation proctitis (CRP) is still problematic and does not respond to medical treatments including reagents, endoscopic argon plasma coagulation (APC) or topical formalin.
- Conditions
- Chronic Radiation Proctitis, Rectal Bleeding, Colostomy Stoma, Anemia
- Trial name
- NCT03397901
- Testing
- Transverse colostomy
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Radiotherapy, Radiation Proctitis
Association Between Clinical Classification and Prognosis in Chronic Radiation Enteropathy
This is a prospective, observational study aimed at exploring the associations between the clinical classification of chronic radiation enteropathy and prognosis.
- Conditions
- Radiotherapy, Radiation Proctitis, Radiation Enteritis
- Trial name
- NCT07378631
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Radiation Enteritis, Radiation Proctitis
Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet.
The study will consist of pair of double-blind placebo-controlled trials of dietary supplementation with 15g/day FructoOligoSaccharide (FOS) for 7.5 weeks in patients with prostate carcinoma or 5 weeks in patients with cervical…
- Trial name
- NCT01414517
- Testing
- FructoOligoSaccharide, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 220 people
- Sponsor
- University College London Hospitals
Chronic Radiation Proctitis
Combined Therapy in Radiation Proctopathy
The aim of this study was to compare the efficacy and safety of two treatment regimens: argon plasma coagulation (APC) alone and APC in combination with sucralfate administered for chronic hemorrhagic radiation proctopathy.
- Trial name
- NCT01613534
- Testing
- Sucralfate
- Where
- Poland
- Volunteers
- 122 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology