Clinical trials: Chronic Radicular Back Pain
Chronic Low Back Pain
Implementation of Pedometer for Monitoring Step Count Pre and Post Lumbar ESI for Radicular Pain
Our aim is to assess usability and compliance of a wireless pedometer for monitoring step count after a lumbar epidural steroid injection for the treatment of radicular pain in low back pain patients.
- Trial name
- NCT02356783
- Testing
- Pedometer
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Hospital for Special Surgery, New York
Lumbar Degenerative Disc Disease, Lower Back Pain
Human Autograft Mesenchymal Stem Cell Mediated Stabilization of The Degenerative Lumbar Spine
Investigate the potential of tissue grafting that includes human mesenchymal stem cells in the repair and potential stabilization of the degenerative Lumbar disk and facet joint denovo and at the time of surgical reconstruction.
- Conditions
- Lumbar Degenerative Disc Disease, Lower Back Pain, Chronic Lower Back Pain
- Trial name
- NCT02529566
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Foundation for Spinal Research, Education and Humanitarian Care, Inc.
Low Back Pain
Traction in Vertical Sitting Position Versus Supine Lying Position in Patients of Chronic Radicular Low Back Pain
The primary objective of the study is to determine the effects of vertical sitting versus supine lying traction on pain, range of motion, and function in patients with chronic radicular low back pain (CRLBP).
- Trial name
- NCT05794347
- Testing
- Traction
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
The Effects of Apomorphine on Experimental and Clinical Pain in Patients With Chronic Radicular Pain
The study aimed to explore the effect of the dopamine agonist apomorphine on spontaneous pain intensity and evoked cold clinical and experimental pain in patients with lumbar radicular neuropathic pain (NP).
- Trial name
- NCT02969629
- Testing
- Apomorphine, Normal Saline
- Where
- Israel
- Volunteers
- 59 people
- Sponsor
- Rambam Health Care Campus
FBSS, Pain, Intractable
PET Patterns, Biomarkers and Outcome in Burst SCS Treated FBSS Patients
The primary aim of this study is to investigate cerebral mechanisms of burst stimulation in Failed Back Surgery Syndrome (FBSS) patients treated with Burst Spinal Cord Stimulation (SCS) for chronic back and leg pain.
- Conditions
- FBSS, Pain, Intractable, Low Back Pain, Radicular; Neuropathic, Lumbar, Lumbosacral
- Trial name
- PET-SCS (NCT03419312)
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Uppsala University
Lumbosacral Radicular Pain, Chronic Radicular Back Pain
Effectiveness of High-Voltage PRF for Chronic Lumbosacral Radicular Pain
This randomized controlled trial compared high-voltage (60 V) and low-voltage (45 V) pulsed radiofrequency (PRF) for treating chronic lumbosacral radicular pain in adult patients.
- Trial name
- NCT07303309
- Testing
- Pulsed Radiofrequency, Post-operative Analgesia
- Where
- Indonesia
- Volunteers
- 22 people
- Sponsor
- Hasanuddin University
Back Pain With Radiation, Pain, Postoperative
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT03546738
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- St. Olavs Hospital
Lumbar Radiculopathy
Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain
To evaluate the efficacy of usage of High-voltage pulsed radiofrequency on DRG in comparison to standard-voltage pulsed radiofrequency intervention in patients with chronic lumbosacral radicular pain
- Trial name
- NCT05713032
- Testing
- Pulsed radiofrequency on lumbar dorsal root ganglion
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Alexandria University
Radiculopathy Lumbar
Spinal Decompression Therapy in Radicular Chronic Low Back Pain
The study design was randomized control trial and sampling technique was lottery method. After inclusion and exclusion criteria, sample populations were divided into experimental (group A) and control group (group B).
- Trial name
- NCT04701879
- Testing
- Spine decompression with core stability exercises, Spine decompression
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Low Back Pain
True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
You are asked to take part in this study because you have chronic, non-radicular low back pain. This study is done to investigate the pain relieving effects of the study drug Exalgo (Hydromorphone ER) for people who experience…
- Trial name
- Covidien (NCT01455519)
- Testing
- Hydromorphone ER, Sugar pill
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Shirley Ryan AbilityLab
Chronic Radicular Back Pain, Lumboischialgia
High-tone External Muscle Stimulation for Pain Reduction
Sciatica is a common pain problem that affects not only the patient but also constitutes a socioeconomic burden and thus affects the whole society. So far, current pharmacologic therapies are inadequate for many patients.
- Conditions
- Chronic Radicular Back Pain, Lumboischialgia, Cervico Brachialgia
- Trial name
- HTEMS (NCT02151565)
- Testing
- HTEMS, TENS
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- West German Center of Diabetes and Health
Back Pain Lower Back Chronic, Chronic Pain
True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
To study the response of objective and quasi-objective 'True' functional outcomes, analgesia and safety in chronic non-radicular back pain to buprenorphine buccal film (BBF) using a small 'n' phase IV design.
- Trial name
- NCT05419297
- Testing
- Buprenorphine Buccal Film [Belbuca], Urine Drug Screening, actigraph
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carolinas Pain Institute
Low Back Pain, Sciatica
Neural Dynamics Technique for the Treatment of Chronic Radicular Low Back Pain
Low back pain ( LBP) is a significant health problem which affects about 70%-80% of the population during the course of their life . The majority of LBP is resolved within 3 months; however, up to 40% of LBP becomes chronic.
- Trial name
- NCT01145105
- Testing
- neural dynamics techniques treatment
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Clalit Health Services
Low Back Pain
Intraarticular Lumbar Joint Corticosteroid Injection(s) as a Treatment of Chronic Low Back Pain in a Selected Population
Subjects (N=120) who have had non-radicular low back pain, believed by clinical assessment and imaging to be consistent with lumbar zygapophysial joint (Z-joint) generated pain, who have failed conservative therapy including…
- Trial name
- NCT01382771
- Testing
- Intra-articular corticosteroid injection, Intra-articular saline injection
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Florida
Lumbar Disc Herniation, Chronic Low Back Pain
High-Intensity Laser Therapy Versus Transforaminal Epidural Steroid Injection in Chronic Lumbar Disc Herniation-Related Low Back and Radicular Pain
This prospective, randomized, single-blinded, controlled clinical trial aims to compare the effectiveness of high-intensity laser therapy and fluoroscopy-guided transforaminal epidural steroid injection in patients with chronic…
- Conditions
- Lumbar Disc Herniation, Chronic Low Back Pain, Radicular Pain, Lumbar Radiculopathy
- Trial name
- NCT07688915
- Testing
- High-Intensity Laser Therapy, Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Lumbosacral Radicular Pain, Sciatic Radiculopathy
Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy
The purpose of this study is to evaluate the safety and tolerability of C-1101 administered as a single dose, transforaminal epidural injection compared to sterile saline
- Conditions
- Lumbosacral Radicular Pain, Sciatic Radiculopathy, Sciatic Leg Pain, Sciatica
- Trial name
- NCT07264270
- Testing
- C-1101
- Where
- 6 sites in United States, Australia
- Volunteers
- 24 people
- Sponsor
- Consano Bio
Chronic Cervical Radicular Pain
Electrophysiological Predictors of Cervical DRG Pulsed Radiofrequency Outcomes
This observational study aims to determine whether electromyography and nerve conduction study findings can help predict the response to cervical dorsal root ganglion pulsed radiofrequency treatment in patients with chronic…
- Trial name
- NCT07776431
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Back Pain, Lower Back Pain
Naltrexone and Clonidine Combination (ATNC05) in the Treatment of Chronic Back Pain
The study includes back pain of the cervical, thoracic, and the lumbar regions.
- Conditions
- Back Pain, Lower Back Pain, Cervical Pain
- Trial name
- NCT01415895
- Testing
- Naltrexone and Clonidine Combination
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Annette C. Toledano MD
Lumbosacral Radicular Syndrome
PRF Treatment for Patients With Chronic Lumbosacral Radicular Pain Compared to Conventional Medical Management
The purpose of the study is to evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic lumbosacral radicular syndrome (LRS).
- Trial name
- NCT00991237
- Testing
- Pulsed Radiofrequency
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Low Back Pain, Physical Therapy
ESWT for Low Back Pain
The goal of this interventional study is to compare the effects of ESWT in women and men between the age 18-65 with non radicular non specific low back pain .
- Conditions
- Low Back Pain, Physical Therapy, Extracorporeal Shock Wave Therapy
- Trial name
- NCT07245498
- Testing
- extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ankara City Hospital Bilkent