Clinical trials: Chronic Spine Pain
Juvenile; Scoliosis, Scoliosis Idiopathic
Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
This is a randomized controlled trial to test effectiveness of the SurgeryPal intervention vs. education control to improve acute and chronic pain and health outcomes in youth undergoing major musculoskeletal surgery.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgeryPal (NCT04637802)
- Testing
- CBT (SurgeryPal), Education
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- Seattle Children's Hospital
Low Back Pain
Weight Bath Traction in Chronic Low Back Pain
It is typical of chronic low back pain that, after the first painful episode, is repeated at 44-78% of patients. For acute lumbar pain, approx. 10-15% of them are converted into chronic.
- Trial name
- NCT03488498
- Testing
- questionnaires
- Where
- Hungary
- Volunteers
- 226 people
- Sponsor
- Polyclinic of the Hospitaller Brothers of St. John of God, Budapest
Chronic Low-back Pain, Degenerative Disc Disease
Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion Device
The purpose of this study is to collect clinical and radiological mid-term (min. 1 year) data on the ArcadiusXP L® lumbar stand-alone cage in a post-market clinical follow-up study (PMCF) limited to 60 patients.
- Conditions
- Chronic Low-back Pain, Degenerative Disc Disease, Spondylolysis Lumbar, Postdiscectomy Syndrome
- Trial name
- ARREST (NCT05944081)
- Testing
- ArcadiusXP L® Interbody Fusion System
- Where
- 3 sites in Germany
- Sponsor
- Aesculap AG
Chronic Low Back Pain
VRFR- Immersive Virtual Reality Use in a Spine Functional Restoration Program - A Feasibility Study
This clinical trial investigates the feasibility of integrating immersive virtual reality (VR) technology into a functional restoration program (FRP) for patients with chronic low back pain (CLBP).
- Trial name
- VRFR (NCT06724679)
- Testing
- Utilisability of an immersive VR device in a functional restoration program (FRP) for patients with chronic low back pain.
- Where
- 5 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Degenerative Disc Disease, Back Pain Lower Back Chronic
The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
The aim of the present study is to find out whether fusion of multilevel SPECT/CT positive lumbar degeneration leads to a significant improvement of pain and disability.
- Conditions
- Degenerative Disc Disease, Back Pain Lower Back Chronic, Facet Joint Arthropathy, Facet Syndrome of Lumbar Spine
- Trial name
- NCT04893720
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Military University Hospital, Prague
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Chronic Low-back Pain
Does Low Back Position Matters in Manual Therapy Treatment
The study will be carried out at the Faculty of Nursing and Physiotherapy of the University of Alcalá. The study has been approved by the Animal Research and Experimentation Ethics Committee of the University of Alcalá.
- Trial name
- NCT04664348
- Testing
- Posteroanterior mobilization (neutral), Posteroanterior mobilization (extension)
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- University of Jaén
Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome
Persistent Post-Lumbar Surgery Pain Syndrome (PSPS) Type II is a Common Condition Encountered in Pain Units, With Limited Available Therapeutic Options. Epidural Pulsed Radiofrequency (PRF) Administered Via Catheter Has Demonstrated Greater Efficacy Compared to the Transforaminal Approach. This Rand
This study is for people who continue to have low back pain after spinal surgery, a condition called persistent spinal pain syndrome type II. Current treatments, such as epidural injections, often provide only limited relief.
- Conditions
- Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome, Chronic Low Back Pain, Post-Laminectomy Syndrome
- Trial name
- EPIPUL (NCT07156513)
- Testing
- Epidural Pulsed Radiofrequency, Betamethasone (Epidural Corticosteroid Injection)
- Where
- 4 sites in Spain
- Volunteers
- 131 people
- Sponsor
- Puerta de Hierro University Hospital
Low Back Pain, Chronic Pain
Non-pharmacological Treatment for Pain After Spine Surgery
This study will compare the effectiveness of two pain management pathways (standard vs. enriched) for patients undergoing lumbar spine surgery in the Military Health System (MHS).
- Conditions
- Low Back Pain, Chronic Pain, Surgery, Back Pain, Low
- Trial name
- NCT04770480
- Testing
- Standard Care (SC), Enriched Pain Management Pathway (EPM)
- Where
- 3 sites in United States
- Volunteers
- 267 people
- Sponsor
- Dan Rhon
Patellofemoral Pain Syndrome, Chondromalacia Patellae
Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain
The purpose of this study is to determine if interventions applied at a distant site, lumbopelvic region (manipulation and TENS), have a similar effect as interventions applied locally at the knee (TENS) on quadriceps force…
- Conditions
- Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
- Trial name
- NCT01434966
- Testing
- Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Creighton University
Chronic Spinal Pain
Time to Step Up to Stepped Care: A Novel Strategy for Cognitive Behavioral Therapy for Insomnia in Chronic Spinal Pain
Chronic spinal pain (i.e., chronic neck pain and chronic low back pain) are highly prevalent, and are known for their immens personal and socio-economic burden.
- Trial name
- StepUp (NCT06771856)
- Testing
- Standard Care CBTi, Stepped Care CBTi
- Where
- Belgium
- Volunteers
- 129 people
- Sponsor
- Vrije Universiteit Brussel
Back Pain, Neck Pain
Safety and Efficacy of Oral Cannabis in Chronic Spine Pain
The overall objectives of this study are to investigate the efficacy of extended cannabis treatment to reduce patient exposure to prescription opioids through its use 1) as a non-opioid analgesic treatment, and 2) as a therapy…
- Trial name
- NCT05052541
- Testing
- THC/CBD, THC
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Colorado, Denver
Chronic Pain Syndromes, CRPS
Neuro-Pain Provides a Dynamic and Interactive Register for the Invasvive Neuromodulatory Therapies for Different Chronic Pain Syndromes. Patients Living in Belgium and Suffering From Persistent Spinal Pain Syndromes Type 2 as Well as Suffering From Complex Regional Pain Syndromes Are Included.
Patients suffereing from chronic pain due to persistent spinal pain syndromes or complex regional pain syndromes and living in Belgium will be included in this register once they are being considered for a treatment with invasive…
- Trial name
- NCT06835868
- Testing
- Spinal cord stimulation
- Where
- Belgium
- Volunteers
- 7,000 people
- Sponsor
- University Hospital, Antwerp
Central Sensitisation, Cervical Spine Stenosis
Comparison of Pain, Sensitisation, Function and Quality of Life According to Stenosis Degree in Chronic Neck Pain
The cervical spine is a structure that bears the weight of the head and has important functions, but is susceptible to mechanical stress and degenerative processes.
- Trial name
- NCT06967415
- Testing
- Pain, central sensitization,functional status and quality of life.
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Chronic Low Back Pain
Effectiveness of Electrotherapy Treatment in Chronic Low Back Pain
This study investigates the effectiveness of a specific electrotherapy treatment for individuals with chronic non-specific low back pain.
- Trial name
- NCT06638229
- Testing
- The StimaWELL 120MTRS system
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Hacettepe University
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Lumbar Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus remifentanil analgesia in lumbar…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05594407
- Testing
- dexmedetomidine-ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aretaieion University Hospital
Neck Pain
Specific Manual Approach to the Suboccipital Area on Patients With Chronic Mechanical Neck Pain
There are different inhibition suboccipital techniques, usually adjuvant of physiotherapy, for treatment of patients with chronic neck pain.
- Trial name
- NCT02832232
- Testing
- translational dorsal glide mobilization technique grade III, pressure maintained suboccipital Inhibition technique, Control Group
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Whiplash Injury, Whiplash Injury of Cervical Spine
Radiofrequency Versus Cervical Fusion for Chronic Whiplash
Chronic neck pain after whiplash injury is a common and disabling condition that can significantly affect quality of life, daily activities, and psychological well-being.
- Conditions
- Whiplash Injury, Whiplash Injury of Cervical Spine, Chronic Neck Pain, Post-Traumatic Neck Pain
- Trial name
- WHIPLASH-RFvsA (NCT07535515)
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- University of Valencia
Low Back Pain, Neck Pain
Goal Oriented Activity for Latinos With Spine Pain
The primary purpose of the study is to determine the efficacy of a culturally adapted cognitive behavioral based tele-rehabilitation program compared to usual care for Hispanics/Latinos with chronic neck or low back pain.
- Conditions
- Low Back Pain, Neck Pain, Chronic Pain, Chronic Low-back Pain
- Trial name
- GOALS (NCT05005416)
- Testing
- GOALS Intervention, Usual Care Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- San Diego State University