Clinical trials: Chronic Spine Pain
Spondylosis Lumbar
Battlefield Acupuncture as an Adjunct to Electroacupuncture for Chronic Low Back Pain Due to Lumbar Spine Osteoarthritis
Chronic low back pain due to lumbar spine osteoarthritis is a common and disabling condition. Many patients do not get enough relief from standard treatments.
- Trial name
- NCT06874959
- Testing
- Battlefield Acupuncture (BFA), Electroacupuncture, Paracetamol 500 mg (as-needed)
- Where
- 2 sites in Vietnam
- Volunteers
- 60 people
- Sponsor
- Bui Pham Minh Man
Intervertebral Disc Degeneration, Chronic Low-back Pain
Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD
ACTIVE is a phase II B efficacy monocenter, prospective, randomized, controlled double blinded trial, in which intra-discal autologous adult BM-MSC therapy will be compared with sham treated controls.
- Trial name
- ACTIVE (NCT04759105)
- Testing
- Autologous BM-MSC
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Low Back Pain, Chronic Low-back Pain (cLBP)
Virtual Tai Chi for Chronic Low Back Pain (Spine 2027)
This study tests whether a virtually delivered integrated tai chi, qigong, and meditation program, added to usual care, improves chronic low back pain, disability, quality of life, and healthcare costs compared with usual care…
- Trial name
- NCT07772154
- Testing
- Virtually Delivered Integrated Tai Chi, Qigong, and Meditation (VDTQM)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- New York Medical College
Chronic Pain, Spine Disease
An Observational Study of Integrated Chronic Pain Management in a Community Health Center
This was a prospective observational study with the primary objective of quantifying a change in pain scores after 6-12 months of two separate interventions within the study site (pain team and chiropractic team).
- Trial name
- NCT04490291
- Testing
- chronic pain team, chiropractic team
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Shoulder Pain Chronic
The Effectiveness of Self-thoracic Spine Mobilization on Improving Sleep Quality in Patients Who Have Shoulder Pain
This project aims to study the impacts of self-thoracic spine and rib mobilization on sleep quality in patients who present to UTSW physicians with shoulder pain.
- Trial name
- NCT03088085
- Testing
- Self-mobilization, Sleep Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Neck Pain
Effectiveness of NMES on Neck Pain
The aim of this randomized-controlled study was to determine the effectiveness of neuromuscular electrical stimulation (NMES) applied simultaneously to exercise on pain, static endurance of cervical deep flexor muscles, fear of…
- Trial name
- NCT06320340
- Testing
- Exercise, Electrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Low-back Pain, Hallux Rigidus
Foot Spine Syndrome "RAFFET Syndrome"
case series aimed to describe a new clinical condition for the first time in the medical literature called Foot Spine Syndrome or "RAFFET Syndrome".
- Trial name
- NCT06180408
- Testing
- manual therapy and exercise for the big toe, lumbar stabilization exercise
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Noha Khaled Shoukry
Pain, Chronic
Predictive Factors on the Results of Epidural Adhesiolysis in Patient With Chronic Spinal Pain
The primary aim of this exploratory study was to determine the demographic, clinical, and technical factors associated with treatment outcome, to create a better select treatment candidates.
- Trial name
- NCT05235308
- Testing
- Percutaneous adhesiolysis
- Where
- Turkey (Türkiye)
- Volunteers
- 193 people
- Sponsor
- Diskapi Teaching and Research Hospital
Neck Pain
Diaphragm's Manual Therapy in Patients With Chronic Neck Pain
The aim of this study is to evaluate the effect of diaphragm's manual therapy in addition to cervical spine manual therapy in terms of pain, cervical spine range of motion, trigger points pain pressure threshold, disability and…
- Trial name
- NCT03223285
- Testing
- Real Treatment Group
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università degli Studi di Ferrara
Lower Back Pain Chronic, Facet Joint Arthrosis
Evaluation of Pain Level Reduction After Low-dose Radiation in Symptomatic Facet Joint Arthritis
The goal of this clinical trial is to compare low-dose radiation therapy (LDRT) with intra-articular steroid injections in participants suffering from chronic lower back pain as cause of facet joint arthritis (FJA).
- Conditions
- Lower Back Pain Chronic, Facet Joint Arthrosis, Osteoarthritis, Spine
- Trial name
- LORAFA (NCT05852808)
- Testing
- Intra-articular steroid injections, Low-dose radiation therapy
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Silvia Gomez Ordonez
Chronic Low-back Pain
The BEST Trial: Biomarkers for Evaluating Spine Treatments
The BEST Trial (Biomarkers for Evaluating Spine Treatments) is a National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)-sponsored clinical trial being conducted through the NIH Helping to End Addiction…
- Trial name
- BEST (NCT05396014)
- Testing
- Enhanced Self-Care (ESC), Acceptance and Commitment Therapy (ACT), Evidence-Based Exercise and Manual Therapy (EBEM)
- Where
- 12 sites in United States
- Volunteers
- 1,014 people
- Sponsor
- University of North Carolina, Chapel Hill
Low Back Pain
Assessment of the Evolution of Lumbar Spine Movement Fluidity Using Xsens Inertial Sensors in Subjects With Chronic Low Back Pain Before and After Rehabilitation
Low back pain, defined as pain located between the thoracolumbar junction and the lower gluteal fold, becomes chronic in 8% of patients.
- Trial name
- Xmouv (NCT07327554)
- Testing
- X-sens sensor
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
Low Back Pain
Spine Rehabilitation Using Spine Flexion / Extension Full Active Range of Motion for Patients With Chronic Low Back Pain
The main objective of this study is to assess efficacy of a spine rehabilitation program, using spine flexion and extension full active range of motion, on physical disability of patients with chronic low back pain.
- Trial name
- REACTIVE (NCT05213845)
- Testing
- Spine flexion/extension active range of motion exercises
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Neck Pain
Effects of a Single Manual Therapy-Exercise Versus Exercise Session in Patients With Chronic Neck Pain
Chronic neck pain is described as pain located between the occiput and the third thoracic vertebra that persists for more than 3 months.
- Trial name
- NCT05085600
- Testing
- Exercise, Manual Therapy + Exercise
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Universitat Internacional de Catalunya
Chronic Low Back Pain (CLBP)
Comparative Study on SNAG From Different Positions Low Back Pain Treatment
Objectives: To compare the effects of lumbar sustained natural apophyseal glides (SNAGs) applied in loaded versus unloaded positions on pain, disability, and function in individuals with chronic nonspecific LBP.
- Trial name
- NCT07215286
- Testing
- Loaded-SNAG, Unloaded-SNAG
- Where
- Saudi Arabia
- Volunteers
- 59 people
- Sponsor
- University of Hail
Back Pain, Neck Pain
E-health Resilience Program For Chronic Spine Pain
This study will examine a e-health resilience based program, JOOL, for chronic spine pain patients through the following aims: Aim 1: To test the effectiveness of a resilience based program known as JOOL Aim 2: To evaluate the…
- Trial name
- JOOL (NCT03667040)
- Testing
- JOOL app
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan
Chronic Non-specific Low-Back Pain, Chronic Non-specific Neck Pain
Diaphragmatic Breathing Training in Chronic Spinal Pain
The goal of this clinical trial is to learn whether adding breathing training to an exercise program can improve pain, mood, and thinking skills in adults with chronic spinal pain.
- Trial name
- NCT07539116
- Testing
- Structured Exercise program, Diaphragmatic Breathing Training
- Where
- 2 sites in Greece
- Volunteers
- 183 people
- Sponsor
- Democritus University of Thrace
Chronic Neck Pain
Effect of Upper Thoracic Manipulation on Neck Pain and Selected Muscle Activities
This study will investigate the immediate and short-term effects of upper thoracic manipulation versus sham upper thoracic manipulation on Pain intensity, Cervical ROM, the myoelectric activity of the sternocleidomastoid muscle…
- Trial name
- NCT06926738
- Testing
- Upper Thoracic Manipulation
- Where
- 2 sites in Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Neck Pain
Cervical Mobilization vs. Standard Physical Therapy for Chronic Neck Pain
Neck pain is a common problem in our society, accounting for 20% of all chiropractic visits. Physical therapy interventions for chronic neck pain have been chosen based on the patient's symptoms and examination findings.
- Trial name
- NCT01092715
- Testing
- Spinal mobilization, Massage, Neck exercises
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mayo Clinic
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital