Clinical trials: Chronic Stress
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Healthy
Influence of Triflusal on Cognitive Functions in Subjects Under Chronic Stress
The purpose of this study is to investigate the effects of the eNOS activating agent triflusal on episodic memory and cognitive functions in participants under chronic stress.
- Trial name
- Tricross-Basel (NCT02904109)
- Testing
- Triflusal
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Stress, Generalized Anxiety
Enhancing Health in Rural Populations: Music as Therapy
The goal of this clinical trial is to learn whether a music-based intervention can improve mental and physical health and strengthen coping skills among adults living in residential care settings in northern Arizona.
- Conditions
- Stress, Generalized Anxiety, Chronic Pain, Depression Disorder
- Trial name
- NCT07538427
- Testing
- Music Based Intervention
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Stress
Impact of a Self-hyPnOsis Practice on Chronic StresS Among Caregivers of Elderly People With Loss of Autonomy at Home
In France, stress particularly affects family caregivers because of the intensive help they provide on a permanent basis to people losing their autonomy at home.
- Trial name
- POSSAID (NCT04909970)
- Testing
- Self-hypnosis, Control (Waiting list)
- Where
- Reunion
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Chronic Periodontitis
Gingival Crevicular Fluid Levels of Protein Carbonyl Following the Use of Lycopene in Chronic Periodontitis
Effect of Locally Delivered Antioxidants as An Adjunct to Non-surgical Periodontal Therapy on GCF Level of Oxidative Stress Marker; Protein Carbonyl
- Trial name
- NCT03203746
- Testing
- Lycopene + SRP, SRP only
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maie Sami tawfik
Insulin Sensitivity, Oxidative Stress
Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study
Investigators will test the hypothesis that chronic restoration of vagal nerve activity with a central acetylcholinesterase inhibitor improves insulin sensitivity and reduces adipose tissue oxidation in obese African American…
- Trial name
- RDVCGH (NCT03014323)
- Testing
- Galantamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Dry Eye
Efficacy of the Chronic Application of Tear Formulations
The purpose of this study is to determine the therapeutic effect of the chronic application of eye-drops on tear evaporation rate in dry eye and normal subjects exposed to a condition of environmental stress.
- Trial name
- NCT01384851
- Testing
- Next Generation Emulsion, Refresh Dry Eye Therapy, Refresh Contacts
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Glasgow Caledonian University
Exercise Recovery, Exercise-induced Muscle Damage
Effect of Cordyceps Supplementation Timing on Physiological Responses and Aerobic Adaptation in Athletes
Athletes frequently perform high-intensity exercise to improve physical performance and aerobic capacity. However, such training can induce exercise-induced muscle damage, oxidative stress, and inflammatory responses that may…
- Conditions
- Exercise Recovery, Exercise-induced Muscle Damage, Oxidative Stress, Sports Performance
- Trial name
- CORD-RECOV (NCT07664345)
- Testing
- Pre-Exercise Cordyceps Sinensis, Post-Exercise Cordyceps Sinensis
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
COPD Patients, Healthy
Determinants of the Vascular Response to Training in Chronic Obstructive Pulmonary Disease (COPD) Patients
Vascular comorbidities constitute a major burden in COPD patients. The atherosclerosis process is preceded by the onset of an endothelial dysfunction (assessed by the flow-mediated dilatation (FMD)), which is a risk factor for…
- Trial name
- cDysEndoBPCO (NCT03774238)
- Testing
- FMD analysis
- Where
- 2 sites in France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Depressive Symptoms, Generalized Anxiety, or Psychological Stress
Mobile Intervention for Mental Health of Family Caregivers in Thailand
The primary objective of this study is to evaluate the effectiveness of the CAMMA intervention in reducing psychological distress among family caregivers of adults with chronic conditions in Thailand.
- Trial name
- NCT06722287
- Testing
- Caregiver Mental Health Mobile Application (CAMMA) Intervention, Usual Care Group
- Where
- Thailand
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma
Neural Mechanisms in Asthma
Asthma is a chronic disease that affects nearly 13% of adults in the U.S., causing substantial impairment that is reflected in the tens of millions of missed days of work, and doctors' and emergency room visits it leads to…
- Trial name
- NCT01155843
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Emotional Stress, Embitterment
Effects of Social Exclusion in The Context of Chronic Embitterment
This experimental, anonymous labor study aims to examine how experiences of social exclusion influence individuals in their fairness-behaviour, psychophysical reactions, and emotion regulation depending on their extent of…
- Trial name
- EMBEX (NCT04350515)
- Testing
- Cyberball: Other Exclusion, Cyberball: Player Exclusion, Mindfulness: Emotion Regulation Task
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Bern
Stress, Psychological, Motivation
Brain and Stress Study
Motivational deficits such as anhedonia are core to several psychiatric disorders and underlie significant functional impairment.
- Trial name
- BASS (NCT06044090)
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Renal Failure Requiring Hemodialysis
Oxidative Stress on Muscle Dysfunction in Hemodialysis Patient
In hemodialysis patient (HD) a reduction of the skeletal muscle mass and strength has previously been reported. This muscle impairment constitutes an independent prognosis factor in HD patients.
- Trial name
- POPEYE (NCT02794142)
- Testing
- renal transplantation, No intervention
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Renal Insufficiency, Chronic, Inflammation
Effects of Cranberry Supplementation on Chronic Kidney Disease Patients.
Patients with chronic kidney disease (CKD) have several complications that are linked to oxidative stress and inflammation, and among the most recently studied is the alteration of the intestinal microbiota.
- Conditions
- Renal Insufficiency, Chronic, Inflammation, Oxidative Stress, Gastrointestinal Microbiome
- Trial name
- NCT04377919
- Testing
- Cranberry
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Pre-diabetes, Insulin Sensitivity
Understanding Dose Related Effects of Strawberry
The proposed research is designed to extend previous research findings building on the knowledge of strawberries as fruits that support a healthy immune and vascular system.
- Conditions
- Pre-diabetes, Insulin Sensitivity, Insulin Resistance, Inflammation
- Trial name
- STRW (NCT06173765)
- Testing
- freeze-dried whole strawberry powder 36 g powder, freeze-dried whole strawberry powder 12 g, freeze-dried control powder 0 g strawberry
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Chronic Stress Disorder
Wear and Tear on Military Personnel Post Caledonian Crisis
Since May 2024, New Caledonia has been experiencing a period of crisis. The organisation of the work of military personnel on the ground has been heavily impacted, with longer working hours, shorter rest periods and increased…
- Trial name
- U-CARE (NCT06907030)
- Testing
- No intervention
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Prader-Willi Syndrome
Stress and Brain Response Using MEG in PWS
Individuals with Prader-Willi Syndrome (PWS) have increased hunger and food seeking behaviour, as well as learning (cognitive) challenges.
- Trial name
- NCT04032639
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cannabis Smoking, Oxidative Stress
Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response
This study plans to evaluate the effects of chronic cannabis smoking on lung health by evaluating its effects on pulmonary health, lung physiology and alveolar macrophage function.
- Trial name
- NCT02480283
- Testing
- Bronchoscopy, Chest X-ray, Venipuncture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder, Insomnia Chronic
Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism
Autism Spectrum Disorder (ASD) represents one of the most perplexing neurobiological disorders with a prevalence of 1 in 54 children.
- Conditions
- Autism Spectrum Disorder, Insomnia Chronic, Caregiver Burden
- Trial name
- NCT05373537
- Testing
- Cognitive behavioral therapy for Insomnia
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania