Clinical trials: Chronic Stroke
Neuropathic Pain, Facial Pain
Motor Cortex Stimulation for Chronic Neuropathic Pain
The purpose of this study is to evaluate the efficacy of cortical stimulation (CS) as an adjunctive treatment for chronic neuropathic pain.
- Conditions
- Neuropathic Pain, Facial Pain, Post-stroke Pain, Brachial Plexus Avulsion
- Trial name
- NCT01554332
- Testing
- Motor Cortex Stimulation using SJM EonC Stimulator
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Abbott Medical Devices
Cognitive Dysfunction, Stroke
Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling…
- Conditions
- Cognitive Dysfunction, Stroke, Dementia, Depression
- Trial name
- VESPAR (NCT05649800)
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Leicester
End Stage Renal Disease Requiring Hemodialysis
Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug
Patients whose kidneys are no longer able to work as they should and require treatment to filter wastes from the blood (hemodialysis) are at high risk for blood clots that form in blood vessels (thrombosis) blocking blood flow…
- Trial name
- RE-THINc ESRD (NCT04534114)
- Testing
- Fesomersen sodium (BAY2976217)
- Where
- 69 sites in United States, Belgium and 13 more
- Volunteers
- 307 people
- Sponsor
- Bayer
Cerebral Stroke, Hemiplegia, Spastic
Compensatory Kinematic Movements in Various Directions After Stroke
This is cross-sectional study. By comparing kinematic analysis between stroke and healthy subjects in various directions, this investigation analyzes the compensatory kinematic movement for reaching task in stroke survivors
- Trial name
- NCT05683158
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Stroke
Acute Effects of Whole Body Vibration in Chronic Stroke
Whole body vibration has been found to be useful in promoting bone health, balance, and muscle performance in older adults. The overall aim of the proposed study is to determine whether whole body vibration (WBV) has immediate…
- Trial name
- NCT01211093
- Testing
- High frequency whole body vibration, Low frequency whole body vibration, control
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Effect of HIIT on Post-Stroke Fatigue
This study aims to investigate the effect of high-intensity interval training (HIIT) on fatigue severity among individuals with chronic stroke.
- Trial name
- NCT07273058
- Testing
- HIIT, MICT, stretching
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Telerehabilitation, Stroke Sequelae
Mobile App as a Guide to Exercises for Patients With Chronic Stroke
Introduction: Stroke continues to be one of the leading causes of disability in the Spanish adult population with the presentation of impairments such as alteration of mobility and a consequent reduction in quality of life.
- Conditions
- Telerehabilitation, Stroke Sequelae, Therapeutic Adherence and Compliance, Mobile Phone Use
- Trial name
- NCT04477252
- Testing
- App-core, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Clínica de Neurorehabilitación
Stroke
The Effects of Functional Action-Observation Training on Gait Ability in Patients With Chronic Stroke
This study aimed to examine the effects of functional action observation training on gait ability in chronic stroke patients.
- Trial name
- NCT03184675
- Testing
- Functional action observation training, General action observation training
- Volunteers
- 40 people
- Sponsor
- Inje University
Stroke
Efficacy of Assistive Soft Gloves in Chronic Stroke Rehabilitation
Stroke is a leading cause of disability, with hemiparesis affecting approximately 85% of survivors, particularly affecting the upper limbs, which play a critical role in the activities of daily living (ADLs).
- Trial name
- NCT07327151
- Testing
- Sybero SRGs, Occupational therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kocaeli University
Stroke
High Intensity Interval Training in Chronic Stroke
The objective of this study was to compare the effectiveness of high intensity interval training (HIT) and traditional aerobic training for persons with stroke.
- Trial name
- HIT (NCT01958606)
- Testing
- High-intensity interval training (HIT), Traditional Aerobic Training
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Cincinnati
Dialysis, Chronic Kidney Disease (Stages 3b-5)
Left Atrial Appendage Occlusion in Dialysis Patients With Atrial Fibrillation: A Multicentre Pilot Study
Objectives: This pilot study aims to evaluate the safety and efficacy of left atrial appendage occlusion (LAAO) in dialysis patients and atrial fibrillation (AF) to establish a novel stroke prevention strategy and determine an…
- Conditions
- Dialysis, Chronic Kidney Disease (Stages 3b-5), Atrial Fibrillation, End Stage Kidney Failure
- Trial name
- LAAO-DAF (NCT07257614)
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Stroke
"Evaluation Of ALBA® Device for Upper Extremity Motor Function In Adults With Subacute And Chronic Acquired Brain Injury"
As part of the rehabilitation techniques, robotic equipment has been introduced for the rehabilitation of the upper extremity with promising results.
- Trial name
- NCT05824416
- Testing
- Experimental: ALBA, Conventional Therapy
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- uMov
Ischemic Stroke
A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)
Evaluation of the safety and tolerability of escalating doses of NR1 administered intracerebrally at a single time-point post-injury to subjects with chronic ISS with or without cortical stroke.
- Trial name
- NCT04631406
- Testing
- Neural Stem Cells
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Clarion Cells, Inc.
Stroke
Development of Smart Holistic Telerehabilitation System: An Application of Stroke Patients- 3 Years Study
Study 1: Background and Purpose-This study were to set up the telerehabilitation program for standing balance training, and to examine the training effects on balance and daily activities in subjects with subacute stroke.The null…
- Trial name
- telerehab (NCT01743430)
- Testing
- telerehabilitation
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cardiovascular Diseases, Stroke Sequelae
Gait Training for Concurrent Optimization of Weight Mgt,bp Regulation and Functional Mobility
Stroke is a leading cause of long-term disability and death worldwide, with chronic survivors often experiencing gait disturbances (affecting up to 80%), reduced physical activity, and cardiometabolic comorbidities like obesity…
- Trial name
- NCT07420595
- Testing
- Weeks 1-6: EAGT (exoskeleton/end-effector devices; 30- 50% body-weight support, speed 1.5-2 km/h, ≥800-1200 steps/session). Weeks 7-12: CGT (overground walking, obstacles, stairs, dual-tasks)., Full 12 weeks CGT, progressing complexity and demands.
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Iqra National University
Stroke
Thoracic Spinal Manipulation in Stroke
The aim of the study is to investigate the effects of thoracic spinal manipulation on balance, fall risk, and thoracic mobility of the patients with chronic stroke.
- Trial name
- NCT07436975
- Testing
- Thoracic Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bitlis Eren University
Stroke
HEROES: Human Extremity Robotic Rehabilitation and Outcome Enhancement for Stroke
HEROES is a multidisciplinary neurophysiological \& neural rehabilitation engineering project, developed by the Lab of Medical Physics \& Digital Innovation, School of Medicine, Faculty of Health Science Aristotle University of…
- Trial name
- HEROES (NCT06160453)
- Testing
- Brain-Computer Interface control of robotic arms with augmented reality, Serious game with augmented reality
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Stroke, Ischemic, Ambulation Disorder, Neurologic
Blood Flow Restricted High-Intensity Treadmill Training on Independently Ambulating Chronic Ischemic CVA Survivors
Individuals surviving Chronic Ischemic Stroke have lingering walking deficits long after their infarct. The main goal of this study is to compare two high intensity treadmill walking programs to see which improves walking more.
- Conditions
- Stroke, Ischemic, Ambulation Disorder, Neurologic, Chronic Stroke
- Trial name
- NCT06214494
- Testing
- Blood Flow Restricted High Intensity Treadmill Training, HITT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MedStar National Rehabilitation Network
Stroke
t-RNS After Hand Recovery in Chronic Stroke
Upper extremity (UE) paresis or weakness is one of the most frequent impairments after stroke. Despite intense rehabilitation, motor and functional recovery of patients with severe hand impairments is poor.
- Trial name
- NCT05489146
- Testing
- transcranial random noise stimulation and functional electrical stimulation facilitated task practice
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Amit Sethi
Hemiparesis, Hemiplegic Cerebral Palsy
The Impact of Robot Assisted Therapy and Metacognitive Skills Training for Children With Hemiparesis
The Occupational Therapy Department at Boston Children's Hospital is teaming up with MGH Institute of Health Professions to explore the benefits of using robot assisted therapy (Amadeo) and a problem solving approach (Active…
- Conditions
- Hemiparesis, Hemiplegic Cerebral Palsy, Hemiparesis;Poststroke/CVA
- Trial name
- NCT04309266
- Testing
- Amadeo by Tyromotion, Active Learning Protocol for Stroke
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Boston Children's Hospital