Clinical trials: Chronic Tinnitus
Chronic Tonal Tinnitus
Clinical Investigation on the Acoustic Stimulation in the Treatment of Chronic Tinnitus
There are many treatments for chronic tinnitus that have been claimed, with varying degrees of statistical reliability. None of those treatments can eradicate the tinnitus completely.
- Trial name
- NCT00927121
- Testing
- Acoustic CR-Stimulator ANM//Technology: Acoustic coordinated reset
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- ANM Adaptive Neuromodulation GmbH
Tinnitus, Subjective
Efficacy Study for Development and Use of Neurofeedback-trainings for Patients Suffering From Chronic Tinnitus
Chronic tinnitus affects about 10-15% of the population in industrialized countries. Investigations of the brain activity by using electroencephalography (EEG) showed that in localized regions of the hearing system brain activity…
- Trial name
- NCT02383147
- Testing
- Tomographic Neurofeedback, Non Tomographic Neurofeedback
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University of Zurich
Chronic Tinnitus
Combined rTMS and Relaxation in Chronic Tinnitus
Repetitive Transcranial Magnetic Stimulation in combination with relaxation therapy is used to modulate the neural pathways contributing to the perception and distress of phantom sounds.
- Trial name
- RELAX (NCT01907022)
- Testing
- Left DLPFC Butterfly Coil
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Regensburg
Tinnitus, Subjective, Vagus Nerve Stimulation
Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus
This clinical study is a prospective, multicenter, randomized, controlled, double-blind clinical study. Sun Yat Sen Memorial Hospital of Sun Yat sen University was the central unit, and Nanjing First Hospital, Sun Yat Sen…
- Conditions
- Tinnitus, Subjective, Vagus Nerve Stimulation, Music Therapy, Double-Blind Method
- Trial name
- NCT05417711
- Testing
- Transcutaneous Vagus Nerve Stimulation Paired with Tailor-Made Notched Music Therapy, Tailor-made Notched Music Training
- Volunteers
- 388 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tinnitus
Individualized Treatment of Patients With Chronic Tinnitus With Repetitive Transcranial Magnetic Stimulation
In the first visit a magnetic resonance imaging measurement will be done for the use of a neuronavigation System with the aim to control for stable coil position over the course of the trial.
- Trial name
- indiTMS (NCT03957122)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- University of Regensburg
Chronic Tinnitus
Effectiveness of Neuronavigated Continuous Theta Burst Stimulation of the Left Heschl's Gyrus in Chronic Tinnitus
Neuronavigated continuous theta burst stimulation of the left Heschl's gyrus is used to modulate auditory cortex activity and plasticity contributing to the perception and distress of chronic tinnitus.
- Trial name
- NCT02199106
- Testing
- Left temporal verum cTBS
- Where
- 4 sites in Germany
- Volunteers
- 23 people
- Sponsor
- University of Regensburg
Tinnitus
Effectiveness Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Chronic Tinnitus
Transcranial Magnetic Stimulation is used to modulate the auditory neural pathways caused by hearing loss and leading to the phantom auditory perception of sound in the absence of an external or internal acoustic stimulus.
- Trial name
- NCT00876720
- Testing
- rTMS - Intervention 1, rTMS - Intervention 2
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Regensburg
Tinnitus
Sub-chronic Neurostimulation Delivered in the Middle Ear for Tinnitus Suppression
The objectives of this study are to evaluate the safety and efficacy of applying electrical stimulation on the promontorium (EPS) for the suppression of tinnitus in a sub-chronic stimulation regimen.
- Trial name
- NCT01549145
- Testing
- Nimbus Multifunctional Stimulator
- Where
- Israel
- Volunteers
- 14 people
- Sponsor
- EstimME Ltd.
Hearing Disorders, Hearing Loss
Chronic Electrical Stimulation of the Auditory Cortex for Intractable Tinnitus
The purpose of this study is to determine whether chronic electrical stimulation of the primary auditory cortex is effective in the treatment of chronic, severe and intractable tinnitus
- Conditions
- Hearing Disorders, Hearing Loss, Hyperacusis, Tinnitus
- Trial name
- ACOUSCO (NCT00486577)
- Testing
- significant chronic primary auditory cortex stimulation during the first two weeks, non significant chronic primary auditory cortex stimulation during the first two weeks
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Bordeaux
Idiopathic Intracranial Hypertension (IIH)
Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide
This study is aimed at patients suffering from long term intracranial hypertension (caracterized by visual loss, chronic headache and/or tinnitus), receiving acetazolamide for more than 1 year, having inadequate response to…
- Trial name
- DIVEIINLATE (NCT06945848)
- Testing
- Acetazolamide, Stent (Tentos 4F or Precise ProRX)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Montpellier
CerebroSpinal Fluid (CSF) Leak, Chronic Otitis Media
Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose
The study objective is to compare the CBCT images generated by the CS 9300 to those generated by conventional CT.
- Conditions
- CerebroSpinal Fluid (CSF) Leak, Chronic Otitis Media, Otospongiosis, Otosclerosis
- Trial name
- CBCT-ENT (NCT01855425)
- Testing
- Radiation
- Where
- 3 sites in United States, Belgium and 1 more
- Volunteers
- 96 people
- Sponsor
- Carestream Health, Inc.
Tinnitus
Tinnitus Sound Therapy Using Mobile Application.
Over the years Tinnitus Sound Therapy (TST) has been undergoing rigorous modification according to the availability of various technologies such as Hearing Aids, personal amplification devices, mp3 players, and now mobile phones.
- Trial name
- TST (NCT06104865)
- Testing
- Tinnitus Sound Therapy using (Resound Tinnitus relief) mobile application
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Basel Samman
Tinnitus
Navigated Repetitive TMS for Chronic Tinnitus
This study is testing whether a special type of brain stimulation called neuronavigated TMS can help reduce tinnitus (ringing in the ears).
- Trial name
- NCT07435298
- Testing
- navigated rTMS
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Chronic Tinnitus
Repetitive Transcranial Magnetic Stimulation With Double Cone Coil in Chronic Tinnitus
Transcranial Magnetic Stimulation is used to modulate both the auditory neural pathways contributing to the perception of phantom sounds, and the regulatory neural network responsible for the generation of the individual amount…
- Trial name
- Ti-CDC (NCT01663311)
- Testing
- Medial Frontal rTMS Double-Cone-Coil, Left DLPFC Butterfly Coil
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Regensburg
Chronic Tinnitus
Influence of Treatment Duration and Stimulation Frequency on rTMS in Chronic Tinnitus
Patients receive two weeks of treatment (prefrontal high-frequency and bilateral low-frequency rTMS vs. prefrontal high-frequency and bilateral high-frequency rTMS).
- Trial name
- NCT02653547
- Testing
- standard multisite four weeks, high-frequency multisite four weeks, standard multisite two weeks
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University of Regensburg
Tinnitus
Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus.
Tinnitus is a widespread problem that affects the quality of life of millions globally. Few treatments have been found to be effective for subjective tinnitus and to have a significant improvement on quality of life.
- Trial name
- TINNITY (NCT05300594)
- Testing
- Plant extracts, vitamins and mineral
- Where
- France
- Volunteers
- 110 people
- Sponsor
- CEN Biotech
Tinnitus
The Efficacy of Repetitive Transcranial Magnetic Stimulation in Patients With Chronic Subjective Tinnitus
The aim of this study is to compare the efficacy of frequency-specific patterned repetitive transcranial magnetic stimulation (rTMS) and 1Hz rTMS for the treatment of chronic subjective tinnitus.
- Trial name
- NCT06635967
- Testing
- frequency-specific rTMS, 1 Hz rTMS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Tinnitus, Sleep Disturbances
Low-intensity TUS for Sleep Disturbances in Patients With Chronic Tinnitus
Background: Tinnitus, as a common symptom, can jeopardize the sleep quality and brain function and even lead to hearing loss and cognitive decline in elderly patients.
- Conditions
- Tinnitus, Sleep Disturbances, Cognition
- Trial name
- NCT06776705
- Testing
- Low-intensity transcranial ultrasound stimulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 14 people
- Sponsor
- Chinese University of Hong Kong
Tinnitus, Acupuncture
Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures
The goal of this clinical trial is to learn if acupuncture works to treat chronic tinnitus in adults. It will also learn about the neurophysiological effects of acupuncture on auditory conduction pathway function.
- Conditions
- Tinnitus, Acupuncture, Auditory Brainstem Response
- Trial name
- NCT07522567
- Testing
- Acupuncture
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Tinnitus, Subjective
ICCAC-ToNF & Tinnitus
Prevalence of chronic subjective tinnitus is rising with age and associated with maladaptive oscillatory changes in auditory as well as non-auditory regions of the brain such as the insula and the anterior cingulate cortex which…
- Trial name
- ICCAC (NCT03895047)
- Testing
- tomographic EEG Neurofeedback Training
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich