Clinical trials: Chronic Tinnitus
Tinnitus
DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury
The goal of this clinical trial is to test a compounded dimethyl sulfoxide (DMSO)-based dual-route therapy for adults with refractory subjective tinnitus linked to long-COVID (post-acute sequelae of SARS-CoV-2) or post-COVID-19…
- Trial name
- DART-TINN (NCT07567274)
- Testing
- DMSO-based otic solution with betahistine, dexamethasone, and lidocaine, DMSO-based transdermal cream with levocarnitine and N-acetylcysteine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Leading Edge Clinic
Tinnitus
Study on the Effect of Sound Therapy on Chronic Primary Tinnitus
This study is to compare the effect of Cochleural Alternating Acoustic Beam Therapy(CAABT) and tinnitus masking therapy(TMT) on chronic primary tinnitus.Half of participants will receive CAABT, while the other half will receive…
- Trial name
- NCT03764826
- Testing
- CAABT, TMT
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Friendship Hospital
Tinnitus
Transcranial Direct Current Stimulation (tDCS) for the Treatment of Tinnitus
The purpose of this study is to determine if repeated sessions of transcranial direct current stimulation (tDCS) are effective for treating chronic subjective tinnitus.
- Trial name
- NCT01575496
- Testing
- BrainSTIM Transcranial Stimulator
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Subjective Tinnitus, Sleep Disorder
Effects of Music Combined With CBT on Chronic Subjective Tinnitus
This study retrospectively analyzed the first and second visit data of chronic subjective tinnitus patients who received music combined with cognitive behavioral therapy in our hospital in recent years.
- Trial name
- NCT06505473
- Testing
- music-CBT
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
CerebroSpinal Fluid (CSF) Leak, Chronic Otitis Media
Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose
The study objective is to compare the CBCT images generated by the CS 9300 to those generated by conventional CT.
- Conditions
- CerebroSpinal Fluid (CSF) Leak, Chronic Otitis Media, Otospongiosis, Otosclerosis
- Trial name
- CBCT-ENT (NCT01855425)
- Testing
- Radiation
- Where
- 3 sites in United States, Belgium and 1 more
- Volunteers
- 96 people
- Sponsor
- Carestream Health, Inc.
Tinnitus
Efficacy and Central Mechanism of Acupuncture for Treating Chronic Subjective Tinnitus Assessed by fNIRS
This randomized controlled pilot trial aims to explore the Efficacy and central mechanism of acupuncture for treating chronic subjective tinnitus using functional near-infrared spectroscopy (fNIRS).
- Trial name
- NCT05829278
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tinnitus
Impact of Neurostimulation on Patterns of Brain Electrical Activity in Patients With Tinnitus
Relating the electroencephalogram findings of patients with tinnitus before and after a therapeutic modality is still scarce in the literature, especially with neuromodulatory methods, more specifically with Transcranial Direct…
- Trial name
- NCT03036137
- Testing
- Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Tinnitus, Subjective Tinnitus
Neurofeedback for Tinnitus - Does Frequency Specificity Matter?
This study will evaluate the efficacy of an alpha/delta ratio (ADR) neurofeedback training protocol on tinnitus distress. 1/3 of the participants in the study will undergo ADR neurofeedback training, 1/3 an active comparator…
- Conditions
- Tinnitus, Subjective Tinnitus, Chronic Tinnitus
- Trial name
- NCT03550430
- Testing
- alpha/delta neurofeedback, beta/theta neurofeedback, Diary completion
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Philipps University Marburg
Tinnitus
The Efficacy of Repetitive Transcranial Magnetic Stimulation in Patients With Chronic Subjective Tinnitus
The aim of this study is to compare the efficacy of frequency-specific patterned repetitive transcranial magnetic stimulation (rTMS) and 1Hz rTMS for the treatment of chronic subjective tinnitus.
- Trial name
- NCT06635967
- Testing
- frequency-specific rTMS, 1 Hz rTMS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Chronic Tinnitus
Smartphone-Based vs Face-to-Face Counseling for Tinnitus
This study aims to compare the effectiveness of smartphone-based counseling and face-to-face counseling in adults with chronic tinnitus.
- Trial name
- NCT07324603
- Testing
- Face-to-Face Tinnitus Counseling, Smartphone-Based Tinnitus Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- TC Erciyes University
Chronic Tinnitus
Effectiveness of Neuronavigated Continuous Theta Burst Stimulation of the Left Heschl's Gyrus in Chronic Tinnitus
Neuronavigated continuous theta burst stimulation of the left Heschl's gyrus is used to modulate auditory cortex activity and plasticity contributing to the perception and distress of chronic tinnitus.
- Trial name
- NCT02199106
- Testing
- Left temporal verum cTBS
- Where
- 4 sites in Germany
- Volunteers
- 23 people
- Sponsor
- University of Regensburg
Idiopathic Intracranial Hypertension (IIH)
Intracranial Venous Stenting Evaluation in Patients With Idiopathic Intracranial Hypertension in the Early Phase
This study is aimed at patients suffering from recently discovered intracranial hypertension, caracterized by visual loss, chronic headache and/or tinnitus.
- Trial name
- DIVE IIN EARLY (NCT06919744)
- Testing
- Best medical care, Intervention (stenting)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Montpellier
Tinnitus
A Clinical Trial Investigating Effect of Tinted Light on Perception of Tinnitus
Background An earlier pilot study provided evidence that about 40% of tinnitus sufferers reported that viewing particular tints of light appeared to result in some improvement of their tinnitus.
- Trial name
- NCT02772536
- Testing
- Visual Stimulus Condition Set
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Tinnitus
Repetitive Transcranial Magnetic Stimulation (rTMS) for Tinnitus
Tinnitus is a phantom auditory perception of meaningless sound, meaning that there is registration of sound in the absence of an external or internal acoustic stimulus.
- Trial name
- NCT00668720
- Testing
- transcranial magnetic stimulation (Magstim rapid2)
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- UMC Utrecht
Tinnitus, Subjective, Vagus Nerve Stimulation
Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus
This clinical study is a prospective, multicenter, randomized, controlled, double-blind clinical study. Sun Yat Sen Memorial Hospital of Sun Yat sen University was the central unit, and Nanjing First Hospital, Sun Yat Sen…
- Conditions
- Tinnitus, Subjective, Vagus Nerve Stimulation, Music Therapy, Double-Blind Method
- Trial name
- NCT05417711
- Testing
- Transcutaneous Vagus Nerve Stimulation Paired with Tailor-Made Notched Music Therapy, Tailor-made Notched Music Training
- Volunteers
- 388 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tinnitus
Peripheral-central Correlation Study on the Treatment of Chronic Tinnitus With "Dao qi Tong Luo" Based on the Theory of "Connecting the Two Ears to the Brain"
By comparing the clinical manifestations, ABR parameters and cerebral cortex blood oxygen levels of chronic tinnitus patients and healthy subjects under two different body states, the peripheral-central correlation of chronic…
- Trial name
- NCT06401993
- Testing
- The "dao qi tong luo" group, The acupuncture group
- Where
- China
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Tinnitus
Individualized Treatment of Patients With Chronic Tinnitus With Repetitive Transcranial Magnetic Stimulation
In the first visit a magnetic resonance imaging measurement will be done for the use of a neuronavigation System with the aim to control for stable coil position over the course of the trial.
- Trial name
- indiTMS (NCT03957122)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- University of Regensburg
Tinnitus
Hearing Aids With "Notched Amplification" for the Treatment of Chronic Tinnitus
Pilot study on safety, tolerability and clinical performance/randomized double-blind active-controlled pilot-study. Patients are being recruited from patients of the Tinnitus Center of Regensburg and groupwise randomized.
- Trial name
- NoA-Tin (NCT02408575)
- Testing
- Notched filtering (verum)
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- University of Regensburg