Clinical trials: Chronic Wound
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing
The retrospective trial is observational, intended to stand alone, complement and integrate data collected in ongoing clinical studies to aid in establishing payor coverage in the United States (U.S.) for Cellution Biologics…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU), Pressure Ulcer (PU)
- Trial name
- RETRO-PLAST (NCT07375160)
- Testing
- dHPT, AIC
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cellution Biologics
Diabetic Foot Ulcer, Venous Leg Ulcer
DETEC® Esterase for Screening Wound Infection at Point of Care
This non-interventional, single-blinded, prospective, observational study assesses the planar distribution of leukocyte esterase in wounds by placing wound exudates soaked wound dressings in the DETEC® Esterase device during…
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer
- Trial name
- NCT04614870
- Testing
- DETEC® Esterase
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Progenitec Inc.
Tibia Fracture, Knee Pain Chronic
Knee Pain After Intramedullary Nailing in the Tibia
The primary objective of this study is to evaluate the long-term outcome after inserting an intramedullary nail in patients with a tibial shaft fracture using an injury-specific questionnaire.
- Trial name
- NCT03649360
- Where
- Denmark
- Volunteers
- 223 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Chronic Disease, Nasal Polyposis
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis
Chronic rhinosinusitis (CRS) with nasal polyps is a particularly challenging form of chronic rhinosinusitis in several ways. Patients have significantly more severe symptom burden and worse quality of life than patients with…
- Conditions
- Chronic Disease, Nasal Polyposis, Rhinitis
- Trial name
- NCT02784262
- Testing
- botox injection Multiguide
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Norwegian University of Science and Technology
COVID-19, Acute Kidney Injury
Kidney Disease After COVID-19
To understand the long-term epidemiology, develop effective risk-prediction and stratification tools, and understand the pathobiology of kidney disease in COVID-19 survivors.
- Conditions
- COVID-19, Acute Kidney Injury, Chronic Kidney Injury
- Trial name
- NCT05328986
- Where
- 5 sites in United States
- Volunteers
- 1,753 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Shoulder Disease, Shoulder Impingement
Cross-sectorial Use of Patient-Reported Outcomes in Chronic Degenerative Shoulder Conditions
This research project aims to test if systematic (extensive) use of patient-reported outcomes across treatment boundaries can 1.
- Conditions
- Shoulder Disease, Shoulder Impingement, Shoulder Osteoarthritis, Shoulder Frozen
- Trial name
- C-PRO (NCT06435494)
- Testing
- Systematic use of patient reported outcome measures in clinical work with the patients
- Where
- 6 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Spinal Cord Injuries
FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI
The main objective of this study is to determine the effectiveness of a new treatment regime that uses electrical stimulation for the improvement of hand function in persons with spinal cord injuries (SCI).
- Trial name
- NCT01208688
- Testing
- FES Therapy, Conventional Occupational Therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Toronto Rehabilitation Institute
End Stage Renal Disease, Acute Kidney Injury
Immunomodulatory Biomimetic Device to Treat Myocardial Stunning in End-stage Renal Disease Patients
Hemodialysis is a therapy that filters waste, removes extra fluid and balances electrolytes. In hemodialysis, blood is removed from the body and filtered through a man-made membrane called a dialyzer, and then the filtered blood…
- Conditions
- End Stage Renal Disease, Acute Kidney Injury, Chronic Kidney Disease Stage 5
- Trial name
- ESRD (NCT03539861)
- Testing
- Hemodialysis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan
Diabetic Foot Ulcers (DFUs)
Effect of Meso Wound Matrix in the Treatment of DFUs
This is a prospective trial designed to evaluate the use of Meso Wound Matrix (DSM Biomedical, Exton, PA) in Wagner grade 1 and 2 DFUs.
- Trial name
- NCT04182451
- Testing
- Meso Wound Matrix
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- SerenaGroup, Inc.
Stress - Prevention of Sleep Disorders, PTSD and Depression
Solomiya App - CBT-based Self-help Intervention
The project aims to investigate the feasibility and acceptability of a smartphone intervention for depressive symptoms and insomnia in people living under prolonged stress due to the ongoing war in Ukraine.
- Trial name
- SOLOAPP-FAIT (NCT07104695)
- Testing
- Solomiya App - CBT-based self-help intervention
- Where
- Ukraine
- Volunteers
- 80 people
- Sponsor
- Solveig Kemna
Stroke, Hip Fractures
Outcome of Rehabilitation of Older People in Primary Health Care
The Outcome of Multi-Disciplinary, Structured Rehabilitation of Older People in a District Inpatient Rehabilitation Centre is better than in a Standard Primary Health Care Rehabilitation Programme in Short Term Beds in Nursing…
- Conditions
- Stroke, Hip Fractures, Osteoarthritis, Chronic Disease
- Trial name
- NCT01457300
- Testing
- Rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 302 people
- Sponsor
- University of Oslo
Traumatic Brain Injury
Allogeneic Umbilical Cord Blood Therapy for Chronic TBI
This open label trial is conducted to investigate the efficacy and safety of umbilical cord blood therapy for chronic traumatic brain injury patients.
- Trial name
- NCT01451528
- Testing
- Allogeneic Umbilical Cord Blood
- Where
- South Korea
- Sponsor
- Bundang CHA Hospital
Whiplash Injuries
Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders
The primary study aim is to unravel the nature of impaired pain inhibition during exercise in patients with chronic Whiplash-Associated Disorders (WAD).
- Trial name
- NCT01601912
- Testing
- Atomoxetine, Citalopram
- Where
- Belgium
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Lateral Epicondylitis
Comparison of Muscle Energy Technique and Oscillating Energy Manual Therapy in Chronic Lateral Epicondylitis
Lateral epicondylitis (LE) is a painful musculoskeletal condition caused by overuse. The condition is also called tennis elbow because it affects 50% of tennis players, notably beginners learning the one-handed backhand.
- Trial name
- NCT05354167
- Testing
- muscle energy technique, oscillating manual energy therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Shoulder Pain, Shoulder Injuries
MDR SureLock All-Suture Anchor
To report the outcomes of a series of patients with recurrent anterior and/or posterior shoulder instability who underwent surgical repair of the affected labrum using the SureLock all-suture anchor.
- Conditions
- Shoulder Pain, Shoulder Injuries, Shoulder Disease, Shoulder Pain Chronic
- Trial name
- NCT04093700
- Testing
- SureLock All-Suture Anchor
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Zimmer Biomet
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Shoulder Dislocation
Treatment of Shoulder Subluxation in Chronic Stroke Patients
The study looks at treatments for reversing chronic shoulder subluxation after a stroke. It compares electrical stimulation with surface electrodes (stimulation through the skin) with intra-muscular stimulation (from inside the…
- Trial name
- NCT00628836
- Testing
- BION stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Venous Leg Ulcer (VLU)
OCM™ Treatment With Routine Care in Venous Leg Ulcers Compared to Routine Care Treatment Alone.
The purpose of the study is to assess the use of OCM™ for the treatment of vascular leg ulcers (VLUs). The study seeks to evaluate the results of treating VLUs with OCM™ plus routine care and compression for complete wound…
- Trial name
- NCT07754526
- Testing
- Omeza OCM™ Wound Matrix, Routine Care
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Omeza, LLC
Wound and Injuries, Pain
Comparison of Pain Reduction in Painful Chronic Wounds With and Without Fat Grafting
Chronic wounds, such as those caused by diabetes, burns, or poor blood circulation, often heal slowly and can cause significant pain, affecting daily life and quality of life.
- Trial name
- PAINFAT (NCT07480447)
- Testing
- Autologous Fat Grafting, Standard Wound Care
- Volunteers
- 62 people
- Sponsor
- King Edward Medical University
Critical Limb Ischemia
Dissolved Oxygen Dressing to Improve Chronic Wound Healing After Revascularization for Critical Limb Ischemia
A Prospective, Randomized, Single-center Pilot Study of The OxyGenesys(TM) Dissolved Oxygen Dressing to Improve Chronic Wound Healing after REvascularization for Critical Limb Ischemia.
- Trial name
- NCT02046226
- Testing
- Oxygenesys(TM) Dissolved Oxygen Dressing
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Halyard Health