Clinical trials: Chronic Wound
Spinal Cord Injuries
Pharmacological Agents for Chronic Spinal Cord Injury (SCI)
The purpose of this study is to investigate the short-term effects of 3 approved FDA drugs (cyproheptadine (CPH), carbidopa-levodopa (CD-LD), and atomoxetine (ATX)) on motor responses when delivered in combination with hand…
- Trial name
- NCT05708274
- Testing
- CPH + hand training, CD-LD + hand training, ATX + hand training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Bronx VA Medical Center
Traumatic Brain Injury (TBI) Patients
Multimodal, Enriched Environment for Rehabilitation in Chronic Traumatic Brain Injury
The goal of this study is to learn if a enhanced environment (Metro Café) with multi model approach (an approach that combines several therapies) in chronic traumatic brain injury improves outcomes of recovery better than…
- Trial name
- NCT06734026
- Testing
- Cafe Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MetroHealth Medical Center
Caffeine, Biomechanics
Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects
Caffeine is one of the few supplements that have enough scientific evidence to state that can notably improve performance, as different remarkable organizations in the sports nutrition context have classified it as an ergogenic…
- Conditions
- Caffeine, Biomechanics, Fatigue, Injuries
- Trial name
- NCT06039358
- Testing
- Caffeine., Cellulose.
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Lateral Epicondylitis
Recover L-PRP in Lateral Epicondylitis (REGP-11-00)
The objective of the study is to further characterize the performance of L-PRP prepared using the Biomet Recover Kit in the treatment of chronic LE.
- Trial name
- NCT02588040
- Testing
- Leukocyte- and Platelet-Rich Plasma (L-PRP)
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Zimmer Biomet
Ankle Injuries
Ankle Instability Treatment in Patients With Chronic Ankle Instability
Ankle joint self mobilization.
- Trial name
- NCT03189784
- Testing
- mobilization with movement techniques
- Where
- 2 sites in Spain
- Volunteers
- 52 people
- Sponsor
- University of Jaén
Chronic Subdural Hematoma
Middle Meningeal Artery Embolisation in Chronic Subdural Hematoma
This international multicenter study evaluates the efficacy and safety of middle meningeal artery embolization (MMAE) using PVA particles or liquid embolic agents as a perioperative treatment to prevent the recurrence of chronic…
- Trial name
- EMMA-CS (NCT07751887)
- Testing
- Middle Meningeal Artery Embolisation
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Hradec Kralove
Pain, Postoperative, Surgical Wound
Transversus Thoracis Muscle Plane Block for Sternotomy Pain in Cardiac Surgery
Sternotomy pain is usually significant after cardiac surgery. Analgesic options for sternotomy in cardiac surgery are often limited. Poorly controlled acute pain is an important factor to development of chronic postsurgical pain.
- Conditions
- Pain, Postoperative, Surgical Wound, Cardiac Event
- Trial name
- NCT04596163
- Testing
- Transversus thoracis muscle plane block
- Where
- Hong Kong
- Volunteers
- 86 people
- Sponsor
- Chinese University of Hong Kong
Diabetes, Nerve Injury
Molecular Mediators of Nerve Injury Signaling
Specific proteins and other signaling molecules are increased and decreased following nerve injury. Some of these are important in producing pain or explaining why pain persists after traumatic nerve injuries or in disease states…
- Conditions
- Diabetes, Nerve Injury, Chronic Neuropathic Pain
- Trial name
- NCT01437332
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rambam Health Care Campus
Chronic Spinal Cord Injury, Neurogenic Bladder
Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation
The purpose of this study is to determine the efficacy of home transcutaneous tibial nerve stimulation (TTNS) in spinal cord injury(SCI) and to determine the impact on quality of life using TTNS at home
- Trial name
- TTNS-RCT (NCT04074616)
- Testing
- High Dose, Low dose
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetic Foot, Diabetic Foot Ulcer
Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers
The study will evaluate the safety and performance of Symphony™ versus Standard of Care (SOC) in the treatment of chronic non-healing diabetic foot ulcers (DFU) after 12 weeks of treatment.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Chronic Foot Ulcer
- Trial name
- NCT06035536
- Testing
- Symphony™ plus Off-loading, Wound Dressing comprising of calcium alginate Fibracol
- Where
- 11 sites in United States
- Volunteers
- 143 people
- Sponsor
- Aroa Biosurgery Limited
Chronic Pain
Individual Patient Expanded Access IND of HB-adMSCs for Chronic Musculoskeletal Pain.
This is an Individual Patient Expanded Access IND providing multiple administrations of HBadMSCs for the treatment of Chronic Musculoskeletal Pain.
- Trial name
- NCT04711811
- Testing
- HB-adMSC
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Ankle Sprain, Hypermobility, Joint
Comparison of MBR + Suture Tape and MBR for CLAI : A Prospective Cohort Study
GJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. Additional suture tape augmentation has been suggested to provide more strength and stability.
- Trial name
- NCT06897293
- Testing
- Modified Broström procedure + Suture tape augmentation operation, Modified Broström procedure operation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Peking University Third Hospital
Tennis Elbow
Influence of Microcurrent Parameters on Effectiveness in Treatment of Chronic Tennis Elbow
Tennis elbow is a relatively common musculoskeletal disorder that can cause significant pain and disability. Treatment of the disorder is not always successful, and it often recurs or becomes chronic.
- Trial name
- NCT00905736
- Testing
- Microcurrent treatment (controlled current), Micocurrent treatment (controlled voltage)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Hertfordshire
Brain Damage
Cross-cultural Adaptation to the Spanish Population and Validation of the BESTest and Mini-BESTest
Due to brain damage acquired (BDA), is often difficulty in gait and balance alterations, as problems that patients designated as the most disabling. It is essential to an effective assessment of the balance.
- Trial name
- BESTest (NCT04052087)
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Centro de Referencia Estatal de Atención Al Daño Cerebral
Lateral Epicondylitis
Mulligan Mobilization Versus Instrument Assissted Soft Tissue Mobilization In Chronic Iateral Epicondylitis
this study will be conducted to compare between mulligan mobilization and instrument assisted soft tissue mobilization on pain intensity, range of motion, hand grip strength, and hand function in the treatment of chronic lateral…
- Trial name
- IASTM (NCT05780528)
- Testing
- mulligan mobilization, instrumented assisted soft tissue mobilization, conventional treatment
- Volunteers
- 60 people
- Sponsor
- Cairo University
Musculoskeletal Disorders, Whiplash
Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders
The purpose of this study is to determine whether a specifically tailored value-based cognitive behavioural therapy program (V-CBT) is able to prevent the development of persistent disability, pain, and psychological distress if…
- Trial name
- NCT02251028
- Testing
- Value-based cognitive-behavioral therapy
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- University of Southern Denmark
Tennis Elbow
Effectiveness of Microcurrent for Treatment of Tennis Elbow
Tennis elbow is a relatively common musculoskeletal disorder that can cause significant pain and disability. Treatment of the disorder is not always successful, and it often recurs or becomes chronic.
- Trial name
- NCT00817232
- Testing
- Microcurrent (Elexoma Medic)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Hertfordshire
Mild to Moderate Traumatic Brain Injury
PoNS Clinical Experience Program (TBI)
Brief Summary: Prospective, cohort, open-label study. The cohort consists of people who have a chronic balance dysfunction due to a mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT03852732
- Testing
- PoNS Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Helius Medical Inc
Wound, Biofilm
Clinical Implications of Biofilm in Chronic Wound
Chronic wounds are important economic and health-care problem. Biofilm has been recognized as a major factor in wound chronicity, delayed healing, and persistent infections, increasing the need for frequent dressing changes…
- Conditions
- Wound, Biofilm, Chronic Pain, Quality of Life
- Trial name
- NCT05054244
- Testing
- standard wound treatment, Hyperbaric oxygenation (HBOT)
- Where
- Croatia
- Volunteers
- 140 people
- Sponsor
- University of Rijeka
Acute Kidney Injury, Renal Insufficiency,Chronic
Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial
This study is testing whether finerenone, when compared to placebo, is a tolerable and safe intervention when administered in patients with acute kidney injury (AKI).
- Conditions
- Acute Kidney Injury, Renal Insufficiency,Chronic, Kidney Diseases
- Trial name
- FiPAKI (NCT07775482)
- Testing
- Finerenone (BAY94-8862 ) 10 mg
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Jean-Maxime Côté