Clinical trials: Chronic Wounds
Chronic Wounds, Burns
THERAVEX Tissue Care Spray Plus for the Management of Cutaneous Wounds, Burns, and Chronic Ulcers
Pilot observational clinical evaluation assessing the safety and potential effectiveness of THERAVEX Tissue Care Spray Plus as an adjunctive topical therapy for the management of cutaneous wounds, burns, traumatic lesions…
- Conditions
- Chronic Wounds, Burns, Pressure Ulcer, Traumatic Wounds
- Trial name
- NCT07617961
- Testing
- THERAVEX TISSUE CARE SPRAY PLUS
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Spinal Cord Injuries, Blood Pressure Disorders
ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury
Empower BP is a pivotal, interventional, multicenter, prospective, randomized, controlled double-blinded study to evaluate the safety and effectiveness of the ARC-IM System in managing symptomatic blood pressure instability in…
- Trial name
- Empower BP (NCT07147296)
- Testing
- ARC-IM System Implantation, ARC-IM Therapy (Group 1), ARC-IM Therapy (Group 2)
- Where
- 13 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- ONWARD Medical, Inc.
Trauma, Nervous System
Northwest Therapies Trauma Psilocybin Study Compassionate Use Study
The on-boarding of unregulatable trauma in the United States has reached 20%, which is 1/5 of the population. A population of this magnitude, by definition has now reached an epidemic classification.
- Trial name
- NWTTPS (NCT05042466)
- Testing
- Trauma
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NWTraumatherapies
Traumatic Brain Injury
Effects of Moderate/Severe Traumatic Brain Injury in the Subacute or Chronic Phase on Locomotor Strategies Involved in Navigation in Complex Virtual Environments
While clinical assessment of locomotor function in this population is carried out using tasks involving walking in a straight line without any obstacles, it does not take into account ecological situations (i.e., situations…
- Trial name
- NAVIGO (NCT07230002)
- Testing
- Locomotion in a virtual reality setting
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pôle Saint Hélier
Trauma Injury
Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury
Traumatic injury is a leading cause of morbidity and mortality in young adults, and remains a substantial economic and health care burden.
- Trial name
- NCT02577731
- Testing
- Bone marrow collection, Blood collection, Clinical data collection
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Florida
Insomnia, Traumatic Brain Injury
Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain Injury
The purpose of this clinical trial is to assess the relative efficacy of two non-pharmacological interventions for insomnia in Veterans suffering from chronic mild traumatic brain injury (mTBI).
- Trial name
- NCT03261674
- Testing
- CBT-I, ABT-I
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- VA Office of Research and Development
Burn Injury, Chronic Pain
Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury
The purpose of this study is to see the effects of transcranial direct current stimulation (tDCS) on the pain and itching associated with burn injury. This study is part of the Boston-Harvard Burn Model System.
- Conditions
- Burn Injury, Chronic Pain, Pruritus, Itching
- Trial name
- NCT01795079
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Spaulding Rehabilitation Hospital
Traffic Accident, Chronic Disease
Risk Level of Suffering From Traffic Injury in Primary Health Care: LESIONAT Project
Main objectives: To know the distribution of risk elements of traffic injuries Secondary objectives: To study the distribution of risk elements related with the possibility of suffering from a TI in relation to medication…
- Conditions
- Traffic Accident, Chronic Disease, Prevalence of Psychoactive Substances in Road Traffic, Relative Risk Estimation of Accident for Impaired Drivers
- Trial name
- LESIONAT (NCT00778440)
- Where
- Spain
- Volunteers
- 1,540 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Lateral Epicondylitis
Active Release Technique and Graston Technique in Patients With Lateral Epicondylitis
This study will be a randomized control trial and will be conducted in Pakistan Railway Hospital Rawalpindi. A sample of 36 participants will be taken. Patients will be divided into two groups by sealed envelop method.
- Trial name
- NCT05070559
- Testing
- Active Release Technique, Graston Technique Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Whiplash
Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash?
This physiological study examines whether acupuncture exerts short-term effects of analgesic mechanisms in patients with chronic whiplash pain.
- Trial name
- NCT01512576
- Testing
- acupuncture, relaxation
- Where
- Belgium
- Volunteers
- 39 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Wound
A Trial to Evaluate the Combination Efficacy of Artificial Dermis and Growth Factor in Chronic Wounds Ulcer
Double layer artificial dermis repair material has been widely used in scar plastic, burn, trauma, chronic wounds and other aspects of wound repair and reconstruction.
- Trial name
- NCT04132635
- Testing
- artificial dermis, growth factor
- Volunteers
- 64 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Diabetic Neuropathy, Neuropathic Pain
Pain In Neuropathy Study
In the context of peripheral neuropathy, we will aim to elucidate correlates between sensory symptoms and: Sensory nerve dysfunction. Cutaneous small nerve fibre innervation density. Psychological co-morbidity.
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Chronic Pain, Carpal Tunnel Syndrome
- Trial name
- PINS (NCT02672059)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- King's College London
Persian Gulf Syndrome, Chronic Sinusitis
Gulf War Illness Nasal Irrigation Study
The purpose of this study is to determine whether nasal irrigation with Xylitol or saline are effective in the treatment of chronic rhinosinusitis and fatigue symptoms associated with Gulf War Illness.
- Conditions
- Persian Gulf Syndrome, Chronic Sinusitis, Fatigue, Acute Sinusitis
- Trial name
- GWINIS (NCT01700725)
- Testing
- Nasal Irrigation - Saline, Nasal Irrigation - Xylitol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Chronic Pain
Central Sensitization in Chronic Whiplash Patients
The purpose of this study is to determine whether the metabolite concentrations within the anterior cingulate cortex and periaqueductal gray matter predict the intensity and interference of neuropathic pain after the development…
- Trial name
- NCT03005691
- Testing
- Spectroscopy, Questionnaires, Conditioned Pain Modulation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Leg Ulcer
Effects of Topical Dynamic Phototherapy on the Microbiota of Chronic Wounds
The main objective of this study is to estimate the change in the relative numbers of commensal or low virulence potential bacteria before and after one session TDP.
- Trial name
- PDT-Bactério (NCT02392390)
- Testing
- Topical Dynamic Phototherapy (TDP), Metvixia cream
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Granulation of Chronic Diabetic Wounds, Diabetic Wounds
1% Acetic Acid vs Normal Saline Dressing inManagement of Diabetic Foot
Chronic diabetic wounds are those wounds that are persistent and do not respond to any sort of treatment. The concept of using topical antiseptics on open wounds is to prevent and treat infections.
- Trial name
- NCT06356480
- Testing
- 1% Acetic acid dressing
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- Dr. Muhammad Naeem
Spina Bifida, Cerebral Palsy
Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
Transition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Spastic Paraplegia
- Trial name
- NCT07706517
- Testing
- Chart review, Semi-structured interview
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spinal Cord Injury, Chronic
taVNS During Exercise and Recovery in Chronic Spinal Cord Injury
This study investigates the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on autonomic cardiovascular regulation during exercise and recovery in individuals with chronic spinal cord injury (SCI).
- Trial name
- taVNS-HRV-SCI (NCT07524491)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- University of the Balearic Islands
Mild Traumatic Brain Injury, Concussion Post Syndrome
Treatment for Patients With Chronic Post-Concussion Symptoms
The current project will examine the effect of a brief psychological intervention on post-concussion symptoms, neurocognitive function, cerebral blood flow (CBF), and psychophysiological and salivary cortisol markers of autonomic…
- Trial name
- NCT03759808
- Testing
- Psychological Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Ankle Sprains
Development of Chronic Ankle Instability After Acute Ankle Sprain
The goal of this observational prospective cohort study is to determine key clinical predictors for chronic ankle instability and return to sports in patients who suffered an acute ankle sprain.
- Trial name
- NCT05637008
- Where
- Belgium
- Volunteers
- 265 people
- Sponsor
- Universiteit Antwerpen