Clinical trials: Chronic Wounds
Mild Traumatic Brain Injury, Chronic Pain
Neuromodulation and Yoga for Mild Traumatic Brain Injury and Chronic Pain
The objectives of this VA SPiRE application are to develop a combined neuromodulation and yoga (iTBS+yoga) intervention for Veterans with mild traumatic brain injury (mTBI) and chronic pain, assess the intervention's feasibility…
- Trial name
- NCT04517604
- Testing
- Magventure MagProx100 with MagOption
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
TENS Trial to Prevent Neuropathic Pain in SCI
The purpose of this research study is to: 1) test whether transcutaneous electrical nerve stimulation (TENS) after spinal cord injury can reduce the onset of post-injury neuropathic pain; and 2) to learn more about this kind of…
- Trial name
- TENS (NCT03267810)
- Testing
- TENS
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Spinal Cord Injury, Sleep Apnea, Obstructive
Sleep-Disordered Breathing in Chronic SCI
The purpose of this study is to examine impact of Sleep Disordered Breathing (SDB) treatment in persons with chronic Spinal Cord Injury (SCI).
- Trial name
- NCT02176928
- Testing
- AutoPAP
- Where
- 4 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Miami
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
The overarching goal of this UH2-UH3 proposal is to work with the NIH Health Care Systems Research Collaboratory to develop and implement a large scale, cluster randomized pragmatic clinical trial demonstration project that…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02655354)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management
- Where
- 24 sites in United States
- Volunteers
- 635 people
- Sponsor
- University of Washington
Leg Ulcer, Varicose Ulcer
Evaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers
This pilot study was designed to test the safety of Celaderm(TM) in treating venous leg ulcers and to give preliminary information about the efficacy of two different Celaderm(TM) dosing regimens.
- Trial name
- NCT00399308
- Testing
- Celaderm (Frozen Cultured Epidermal Allograft), Control (compression bandaging)
- Where
- 9 sites in United States
- Volunteers
- 40 people
- Sponsor
- Shire
Spinal Cord Injuries, Tetraplegia
Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia
This study is for people who have a paralyzed arm and hand from a spinal cord injury, who have also received a recording electrode array in the brain as part of the BrainGate study.
- Conditions
- Spinal Cord Injuries, Tetraplegia, Quadriplegia
- Trial name
- NCT03482310
- Testing
- Using the Neuroport cortical recording array to determine the desired grasp pattern for a functional electrical stimulation (FES) system
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Office of Research and Development
Hematoma, Subdural, Chronic
Role of Dexamethasone in the Conservative Treatment of Chronic Subdural Hematoma
Current opinion regarding the use of steroids in the treatment of chronic subdural hematomas are mostly based on observational studies.
- Trial name
- NCT02362321
- Testing
- Dexamethasone
- Volunteers
- 20 people
- Sponsor
- CHU de Quebec-Universite Laval
Cognition Disorder, Attention Deficit Disorder
Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI
Deficits in memory, attention, cognitive, and executive functions are the most common disabilities after traumatic brain injury (TBI).
- Conditions
- Cognition Disorder, Attention Deficit Disorder, Traumatic Brain Injury
- Trial name
- DAPET-TBI (NCT02225106)
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Pennsylvania
Chronic Pain
rTMS for the Treatment of Chronic Pain in GW1 Veterans
This study was designed to evaluate the effect of repetitive Transcranial Magnetic Stimulation (rTMS) in the resolution of Chronic Pain.
- Trial name
- rTMS (NCT01608321)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Neuralgia, Spinal Cord Injuries
A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury
The purpose of this study is to evaluate if pregabalin relieves nerve pain associated with spinal cord injury compared to placebo (pill that contains no active medicine).
- Trial name
- NCT00407745
- Testing
- pregabalin
- Where
- 67 sites in United States, Chile and 8 more
- Volunteers
- 220 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Traumatic Brain Injury
Amantadine + rTMS as a Neurotherapeutic for Disordered Consciousness
The purpose of this study is to examine the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with Amantadine relative to rTMS Alone and Amantadine Alone for persons in chronic states of…
- Trial name
- NCT02025439
- Testing
- rTMS, Amantadine
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Edward Hines Jr. VA Hospital
Lower Leg Wound
A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention
A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention
- Trial name
- WoundWand (NCT01924806)
- Testing
- WoundWand™ Debridement Device, Standard of Care sharp debridement
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 11 people
- Sponsor
- Smith & Nephew, Inc.
Spinal Cord Injuries, Tetraplegia
Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)
This study will evaluate if Ursolic Acid supplementation may be effective in reducing muscle loss and improving blood sugar control in the SCI community.
- Conditions
- Spinal Cord Injuries, Tetraplegia, Paraplegia, Muscle Loss
- Trial name
- NCT05776862
- Testing
- Ursolic Acid, Strength Training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Spinal Cord Injuries, Heart Diseases
Coronary Heart Disease as Measured by Coronary Calcium Score Among Individuals With Chronic Traumatic Spinal Cord Injury
This study includes male subjects age 45 to 70, who have sustained a traumatic Spinal Cord Injury (SCI) at least 10 years prior. Subjects will be interviewed for demographic data, including heart disease risk factors.
- Trial name
- NCT00628446
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Wake Forest University Health Sciences