Clinical trials: Chylothorax
Chylothorax
Dietary Treatment of Infants With Chylothorax
Chylothorax occurs in ~3 to 5 % of infants undergoing cardiac surgery. Standard treatment requires discontinuation of breast milk feeding, due to the abundance of long chain triglycerides, and transition to a medium chain…
- Trial name
- NCT02143557
- Testing
- Fat-Modified Breast Milk, MCT formula
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- The Hospital for Sick Children
Chylothorax
Chylothorax Following Heart Surgery
The purpose of this study is to determine at risk populations for certain congenital heart defects or certain operative procedures and to define the associated morbidity secondary to chylothorax - prolonged chest tube drainage…
- Trial name
- NCT00215098
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Children's Healthcare of Atlanta
Chylous Pleural Effusion Following Cardiothoracic Surgery
Fortified Skimmed Mother's Milk in the Management of Chylothorax
The purpose of this study is to determine if the use of fortified skimmed mother's milk is a safe alternative to specialized formula in the treatment of chylothorax following cardiothoracic surgery.
- Trial name
- NCT01673165
- Testing
- Skimmed mother's milk, Specialized Formula
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Oregon Health and Science University
Postoperative Chylothorax, Congenital Heart Disease
Propranolol Treatment for Postoperative Chylothorax
Postoperative chylothorax is a serious complication after open heart surgery for pediatric patients with congenital heart disease (CHD).
- Conditions
- Postoperative Chylothorax, Congenital Heart Disease, Open Heart Surgery, Chylothorax
- Trial name
- NCT06833320
- Testing
- Propranolol Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- June Wu
Chylothorax
Optimizing Growth in Infants Receiving Modified Fat Breast Milk for the Treatment of Chylothorax
Breast milk is the reference normative standard for infant feeding. When an infant is diagnosed with chylothorax, provision of breast milk must be temporarily discontinued due to the presence of long chain triglycerides (LCT)…
- Trial name
- NCT02577419
- Testing
- Target Fortification, Higher Initial Concentration, Portagen Formula
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
Lymphatic Diseases, Chylothorax
Octreotide Improves Human Lymphatic Fluid Transport a Translational Trial
This study aims to investigate whether octreotide, a medication used off-label to treat chylothorax, has a direct effect on human lymphatic drainage.
- Trial name
- NCT05683444
- Testing
- Octreotide infusion, Saline infusion
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lymphatic Disorders, Plastic Bronchitis
European Registry Study on Lymphatic Interventions
This European multicenter observational study aims to evaluate the real-world use, timing, and outcomes of lymphatic interventions in patients with congenital heart disease and/or primary lymphatic disorders.
- Conditions
- Lymphatic Disorders, Plastic Bronchitis, Protein Losing Enteropathy, Chylothorax
- Trial name
- EURO-LYMPH (NCT07131293)
- Testing
- Lymphatic intervention
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pleural Effusion, Pneumothorax
Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube Drain
The study will be carried out by the principal investigator and his team at the Division of Cardiovascular and Thoracic Surgery of the Department of Surgery, College of Medicine, University of Ibadan and the University College…
- Conditions
- Pleural Effusion, Pneumothorax, Chest Trauma, Video-assisted Thoracoscopic Surgery
- Trial name
- SUTURE (NCT04193241)
- Testing
- Closure of chest tube wound
- Where
- Nigeria
- Volunteers
- 142 people
- Sponsor
- University of Ibadan
Pneumothorax, Hydrothorax
KatGuide Method Versus Conventional Method at Insertion of Chest Tube
The purpose of this study is to investigate whether if KatGuide (a new developed medical device) improves the placing of a large bore chest tube in the pleural cavity compared to the conventional method.
- Conditions
- Pneumothorax, Hydrothorax, Hemothorax, Empyema
- Trial name
- KatGuide (NCT01522885)
- Testing
- KatGuide versus conventional method (forceps), Chest tube insertion
- Where
- 4 sites in Denmark
- Volunteers
- 109 people
- Sponsor
- Niels Katballe
Lung Cancer, Chylothorax
Olive Oil Before Lung Cancer Surgery to Prevent Chylothorax
Chylothorax is a rare but serious complication after lung cancer surgery and mediastinal lymph node dissection. This multicenter randomized trial will evaluate whether drinking 40 mL of extra-virgin olive oil 4 hours before…
- Trial name
- ECTOP-1031 (NCT07807696)
- Testing
- Extra-Virgin Olive Oil
- Where
- China
- Volunteers
- 1,036 people
- Sponsor
- Fudan University
Congenital Chylothorax
Measurement of Hormonal Concentration in Chylothorax Fluid in Infants With Congenital Chylothorax
Late onset Hypothyroidism was found in infant with congenital hypothyroidism. The hypothesis is that infants with congenital hypothyroidism may lose thyroxin and other hormones via the chylothorax fluid causing transient…
- Trial name
- NCT00267345
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Sheba Medical Center
Chylothorax, Esophageal Cancer
FLOTOR Pilot Study
This is a non-randomised study assessing the technique of using indocyanine green as a fluorescent dye to highlight the thoracic duct during oesophectomy.
- Conditions
- Chylothorax, Esophageal Cancer, Thoracic Duct Intra-Operative Injury
- Trial name
- FLOTOR (NCT03292757)
- Testing
- Indocyanine Green
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Lymphangioleiomyomatosis, Lymphangiomyomas
Treatment With Octreotide in Patients With Lymphangioleiomyomatosis
Lymphangioleiomyomatosis (LAM), a disease primarily of women of child-bearing age, is characterized by cystic lung disease and abdominal tumors (e.g., angiomyolipomas).
- Conditions
- Lymphangioleiomyomatosis, Lymphangiomyomas, Pleural Effusions, Ascites
- Trial name
- NCT00005906
- Testing
- Octreotide
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)