Clinical trials: Cicatrix, Hypertrophic
Burn, Hypertrophic Scars
Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn Scars
Burn scars can sometimes heal in a way that causes them to become thick, raised, and stiff. These scars may itch, feel uncomfortable, limit movement, and affect how the skin looks.
- Conditions
- Burn, Hypertrophic Scars, Scar Improvement by Laser, CO2 Laser in Scars
- Trial name
- NCT07660120
- Testing
- Fractional Ablative CO₂ Laser, Triamcinolone Acetonide, Fluorouracil (5-FU)
- Volunteers
- 65 people
- Sponsor
- University of California, Davis
Skin Fold, Skin Laxity
A Safety and Effectiveness Study of CELLBOOSTER® Lift (Stabilized Booster Complex Using CHAC Technology)
The current post-market clinical investigation has been designed to evaluate the efficacy and safety of CELLBOOSTER® Lift, a HA-based product marketed by SUISSELLE SA.
- Conditions
- Skin Fold, Skin Laxity, Skin Texture Disorder, Skin Depression
- Trial name
- NCT06000839
- Testing
- (D0) Intradermal injection - micropapula technique, (D14) Intradermal injection - micropapula technique, (D28) Intradermal injection - micropapula technique
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Suisselle
Hypertrophic Scar, Burn Scar
Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser
Hypertrophic Burn Scars (HTBS) are often treated with Fractional CO2 laser therapy to improve cosmetic appearance. It has been noted that this leads to a reduction in the pain and itch associated with this type of scars.
- Trial name
- NCT04364217
- Testing
- Luminis ultrapulse fractional ablative carbon dioxide laser
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Keloid Scar Following Surgery, Scars, Hypertrophic
Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including Volumetry
Measuring the volumes of hypertrophic scars and keloids, two specific kind of scars, over different points in time in patients who have undergone surgery and evaluate 3D-cameras as a possible measuring and documenting tool…
- Conditions
- Keloid Scar Following Surgery, Scars, Hypertrophic, Scar Keloid
- Trial name
- NCT06806735
- Testing
- 3D-Pictures
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Keloid, Hypertrophic Scar
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids and hypertrophic Scars)
- Conditions
- Keloid, Hypertrophic Scar, Scars, Scarring
- Trial name
- NCT04593706
- Testing
- Betamethasone acetate + Betamethasone sodium phosphate, Dexamethasone sodium phosphate, Methylprednisolone acetate
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acne Scars - Mixed Atrophic and Hypertrophic
enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm Nd:YAG picosecond pulse duration laser and an investigational micro-lens array (MLA)…
- Trial name
- NCT03284333
- Testing
- other
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Scar, Keloid
"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"
A Phase II prospective, randomized, double-blind, placebo controlled and comparative clinical study evaluating hydrogel scar-management modalities for effective management of hyperproliferative scars and keloids.
- Conditions
- Scar, Keloid, Hypertrophic Scar, Cicatrix
- Trial name
- NCT04169490
- Testing
- FS2 Emulsion Moisturizer, Active Comparator Onion Skin Extract Gel (Mederma), Active Comparator Silicone Gel (Kelo-Cote)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Center for Clinical and Cosmetic Research
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy Investigation on the Effects of ClearSkin Non-ablative ER:Glass 1540nm Laser Module in the Treatment of Acne Scars.
The ClearSkin module, Er: Glass 1540nm, is largely used in the treatment of acne vulgaris and acne scars. The non-ablative ER:Glass 1540 nm laser deeply penetrates the skin, causing thermal damage to the sebaceous glands…
- Trial name
- NCT06102343
- Testing
- Alma Harmony
- Where
- Portugal
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Scars, Hypertrophic, Burn Scar
Microneedling Therapy With or Without Amnion Bilayer Sheeting on Scar Tissue
The aim of this study is to compare the outcome of microneedling therapy with or without amnion bilayer sheeting on post-burn hypertrophic scar tissue.
- Trial name
- NCT04995302
- Testing
- Microoneedling and Amnion Bilayer, Microoneedling
- Where
- Indonesia
- Volunteers
- 17 people
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Scar
Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection
Linear hypertrophic scar is a common surgical problem that can be difficult to manage, especially for the median sternotomy scar.
- Trial name
- NCT02886988
- Testing
- Botulinum toxin type A, normal saline
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Xijing Hospital
Keloid Scars, Hypertrophic Scar
Microneedling vs. 5-Fluorouracil or Steroid Injections for Hypertrophic Scars and Keloids
The goal of this clinical trial is to learn about the efficacy and safety of microneedling-assisted 5-fluorouracil delivery in comparison with intralesional 5-fluorouracil, intralesional corticosteroid, and microneedling with…
- Trial name
- MIST (NCT07718269)
- Testing
- Microneedling with 5-Fluorouracil, Intralesional 5-fluorouracil, Intralesional Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Hypertension, Hypertrophy, Left Ventricular
Does Allopurinol Reduce Thickening of the Left Ventricle of the Heart in Patient With Treated Hypertension?
The presence of Left ventricular hypertrophy (LVH) confers high cardiovascular risk in hypertensive patients. LVH remains highly prevalent even when blood pressure (BP) is controlled.
- Trial name
- ALLAY (NCT02237339)
- Testing
- Allopurinol
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University of Dundee