Clinical trials: Cigarette Smoker
Tobacco Use, Smoking
A Facebook Intervention for Young Sexual and Gender Minority Smokers
The 2-year research plan will test the Put It Out Project (POP) in a pilot randomized trial (N=120) compared to TSP and two historical control conditions.
- Conditions
- Tobacco Use, Smoking, Tobacco Dependence, Tobacco Use Disorder
- Trial name
- POP (NCT03259360)
- Testing
- POP:, TSP:
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Disorder
Comparative Acceptability of Tobacco and Menthol Flavored E-cigarettes
The study is a randomized crossover trial. Current menthol smokers will complete a session with each flavor of an electronic cigarette: menthol and tobacco. The objective of this survey is to assess for flavor preference.
- Trial name
- NCT04996940
- Testing
- E-cigarette product
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Nicotine Dependence, Tobacco Use Disorder
Effectiveness of Using Reduced Nicotine Cigarettes in Men and Women Smokers to Combat Nicotine Addiction
This is a 2-year study involving the progressive reduction in the nicotine content of cigarettes. The investigators believe that at the end of the study smokers of cigarettes with progressively reduced nicotine content will be…
- Trial name
- NCT00264342
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Electronic Cigarettes
Assessment of Two New Electronic Cigarettes in Cigarette Smokers
The purpose of this study is to determine differences in nicotine delivery, user behavior, subjective effects, and physiological effects, when cigarette smokers use an two new electronic cigarette devices (JUUL and IQOS) relative…
- Trial name
- NCT03435562
- Testing
- JUUL electronic cigarette, IQOS electronic cigarette, Own Brand cigarette
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
COPD, Smoking
Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke
Cigarette smoking is the major risk factor for developing chronic obstructive pulmonary disease (COPD). Patients with COPD have difficulty clearing mucus and debris from their airways.
- Trial name
- NCT02168673
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Nicotine Dependence
Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers
Background: Smoking is a major public health problem in the U.S. Almost a half a million Americans die from it in a year. One thing that contributes to why people smoke is the marketing of cigarettes.
- Trial name
- NCT02974582
- Testing
- Exposure to smoking advertising with coupon, Exposure to smoking advertising without coupons, Exposure to non health related images
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Minority Health and Health Disparities (NIMHD)
Nicotine Dependence, Other Tobacco Product
Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1
This study is to examine if inhaled doses of menthol that produce low and high cooling effects change the appeal of e-cigarettes containing low and high doses of nicotine in adolescent smokers.
- Trial name
- NCT02179034
- Testing
- Nicotine, Low Dose Menthol, High Dose Menthol
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy, Cigarette Smoking
A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who Are Current Cigarette Smokers
The purpose of this Phase 1 research study is to identify a dose of inhaled endotoxin that is safe (does not cause prolonged cough, shortness of breath or other problems), but causes changes in sputum cell samples that the…
- Trial name
- IRB 09-0259 (NCT00924768)
- Testing
- 20K EU CCRE
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tobacco Use, Tobacco Smoking
Connecting Alaska Native People to Quit Smoking
The prevalence of smoking among US adults is highest among American Indians and Alaska Native (AI/AN) persons; however, there are a lack of tobacco cessation interventions developed specific to this disparity group.
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking Cessation
- Trial name
- CAN Quit (NCT03645941)
- Testing
- Facebook Group
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cigarette Smoking
Contingency Management for Smoking Abstinence With Adolescent Smokers
The primary objective of this research is to evaluate the effectiveness of this type of smoking cessation program by comparing a treatment group with a control group.
- Trial name
- CM (NCT01056588)
- Testing
- CO-Contingent, Control condition
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Smoker
Methods Project 4: Clinical Trial
Cigarette smokers who are eligible will enter a Camel Snus sampling phase. Smokers interested in continuing with the study after the sampling phase will undergo a 2 week baseline assessment phase and will then be randomized to…
- Trial name
- NCT01867242
- Testing
- Cigarettes, Snus
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence, Cigarettes
Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit
This study aims to pilot a method of collecting the post-discharge follow-up data required by the Joint Commission Tobacco Measure Set, using text messages sent to and received from patients' cellular-telephones.
- Trial name
- NCT02986711
- Testing
- Motivational Text Messages, Control
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Smoking, Tobacco Smoking
Reduced Exposure to HPHC in Smokers Switching From Cigarettes to Different Versions of THS
This was a randomized, controlled, open-label, 4 parallel arm study with a stratified randomization by sex (a quota for each sex [females and males] of at least 40% overall).
- Conditions
- Smoking, Tobacco Smoking, Tobacco Use
- Trial name
- NCT05599451
- Testing
- THS Blade device, THS Induction Mono device, THS Induction Mid device
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Tobacco, Smoking
GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments
The purpose of the study is to learn more about the relationships between the brain, behavior, and natural daily exposure to particular environments, including the places where smokers regularly spend time and specific retail…
- Conditions
- Smoking, Tobacco, Smoking, Smoking, Cigarette
- Trial name
- NCT04279483
- Testing
- Tobacco retailer, Non-tobacco retailer
- Where
- United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Smoking
European Exposure Study
The current study was designed to determine the exposure of adult smokers and non-smokers to cigarette smoke constituents through evaluation of selected biomarkers of exposure.
- Trial name
- NCT01237912
- Where
- United Kingdom
- Volunteers
- 1,667 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Schizophrenia, Schizoaffective Disorder
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
Smokers with schizophrenia have more difficulties quitting smoking than smokers without a mental disorder. Varenicline (Champix) is a new stop smoking medication with a unique mechanism of action.
- Trial name
- NCT01093365
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Electronic Cigarette Use, Tobacco Smoking
Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems
The purpose of this study is to estimate nicotine uptake and assess subjective effects during ad libitum use sessions of 4 flavors of JUUL ENDS (also referred to as nicotine salt pod system; NSPS) products (i.e., Virginia…
- Trial name
- NCT04123041
- Testing
- JUUL ENDS, Combustible cigarette, comparator e-cigarette, Nicorette gum
- Where
- 2 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Field Cancerization for Cannabis Smokers
Effect of Cannabis and Cigarette Smoking on Oral Mucosa
The aim of this study is to detect P53 expression in clinically normal oral mucosa of cigarette smokers, simultaneous cigarette and cannabis smokers and non-smokers as a surrogate marker for field cancerization.
- Trial name
- NCT03334279
- Testing
- Cigarette smokers, Simultaneous cigarette and cannabis smokers
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Biology of the Oral Epithelium of E-Cigarette Smokers
Electronic cigarettes (EC) are battery powered nicotine delivery devices that aerosolize nicotine and other flavor constituents.
- Trial name
- NCT03028558
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cigarette Smoker, Current Smoker
Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers
This randomized pilot clinical trial studies nicotine delivery from novel non-tobacco electronic system (ENDS) in smokers. Studying the levels of nicotine delivered by various types and brands of ENDS to the bloodstream, and…
- Conditions
- Cigarette Smoker, Current Smoker, Healthy Subject
- Trial name
- ENDS (NCT02575885)
- Testing
- Electronic Cigarette, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute