Clinical trials: Cigarette Smoking Behavior
Cigarette Smoking
Text Messaging-Based Smoking Cessation Program for Homeless Youth
Unaccompanied homeless youth smoke at much higher rates than non-homeless adolescents and young adults. Many homeless youth smokers are motivated to quit; yet, strategies specifically developed for this vulnerable population are…
- Trial name
- NCT03874585
- Testing
- Group counseling and nicotine replacement, Group counseling, nicotine replacement, and text messaging support
- Where
- 3 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- RAND
Cigarette Smoking
Smoking, Stress, HIV and Mobile Technology
The present investigation aims to address disparities in cigarette use outcomes among Black/African American adults with HIV. The specific aims of this study are: (1) To modify a recently developed, culturally adapted, mobile…
- Trial name
- NCT05709002
- Testing
- MASP+, Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Houston
Nicotine Dependence, Tobacco Toxicity
Cigarette Harm Reduction With Electronic Cigarette Use
This is an observational, crossover study that will be examine use behaviors, chemical exposures, and biological effects of SREC compared to TC use in subjects confined to a research ward setting.
- Conditions
- Nicotine Dependence, Tobacco Toxicity, Nicotine Dependence, Cigarettes, Cardiovascular Risk Factor
- Trial name
- NIDA-SREC (NCT03473483)
- Testing
- SREC
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking, Tobacco Use
BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects
This is a randomized, controlled, multi-center, open-label, 8-cohort parallel group study to assess changes in select biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH) in generally healthy smokers switching to…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05142436
- Testing
- Product A: Non-Combusted Cigarette Variant 42001402 and product use Mode B, Product B: Non-Combusted Cigarette Variant 42001399 and product use Mode B, Product C: Non-Combusted Cigarette Variant 42001401 and product use Mode B
- Where
- 18 sites in United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Lung Cancer
Metabolism of NNK Among African Americans
Metabolism and DNA adduct formation are critical in cancer induction by NNK. The investigators goal is to understand whether the observed ethnic/racial differences in lung cancer incidence are due to variations in NNK metabolism.
- Trial name
- Project 5 (NCT01158456)
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Nicotine Dependence, Nicotine Dependence, Cigarettes
Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods.
A Randomized Study Comparing Nicotine Pharmacokinetics of Seven Electronic Cigarette Products and One Traditional Cigarette Across Two Delivery (10 puff and ad- libitum) Conditions, in Healthy Adult Smokers
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Trial name
- NCT03700112
- Testing
- JUUL Virginia Tobacco flavored 5.0% ENDS, PMI iQOS Heat sticks, Reynolds VUSE Solo ENDS - Original
- Where
- New Zealand
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Smoking ( Cigarette), Breastfeeding
Prevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding Promotion
The objective of this randomized controlled trial is to examine the efficacy of a new intervention to prevent postpartum smoking relapse and related health consequences through breastfeeding promotion.
- Trial name
- NCT07661550
- Testing
- Breastfeeding promotion
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Tobacco Smoking, Nicotine Dependence
Neurophysiological and Immunological Effects of the Transition From Combustible to Electronic Cigarettes
The objective of this study is to examine the cognitive, immunological, and neurophysiological effects of transitioning from tobacco cigarettes to electronic cigarettes.
- Trial name
- ECIG (NCT02433015)
- Testing
- Electronic Cigarette, Tobacco Cigarette
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Vaping, Nicotine Absorption
Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants
This is a single-center, open-label, concentration-ranging study to evaluate the nicotine PK profile and PD effects in healthy adult experienced users of closed tank/cartridge e-cigarettes using four different variants of P4M3…
- Trial name
- NCT03379740
- Testing
- E-cigarette, P4M3-1.7%, P4M3-1.7%LA
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Electronic Cigarette Use
Effects of E-cigarette Use on Health
Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown.
- Trial name
- VAPECHECK (NCT06610838)
- Testing
- Health Assessments
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vaping
Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents
The aim of this study is to determine if graphic messages prevent future vaping use among African American and Latino adolescents.
- Trial name
- NCT04899999
- Testing
- Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Anxiety Disorders, Anxiety
Personalized Feedback for Smokers With Elevated Anxiety Sensitivity
This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and anxiety sensitivity (AS).
- Conditions
- Anxiety Disorders, Anxiety, Tobacco Dependence, Smoking, Cigarette
- Trial name
- NCT03382093
- Testing
- Personalized Feedback Intervention, Smoking Information Control
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Houston
Tobacco Use Disorder
Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes
Cigarette smoking remains the leading cause of preventable morbidity and mortality in the US. Use of multiple tobacco products is becoming increasingly prevalent, with dual use of e-cigarettes and cigarettes representing the most…
- Trial name
- RDEC (NCT06614504)
- Testing
- Varying the nicotine content of cigarettes, Varying the nicotine content of e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Cigarette Smoking, Smoking Behavior
Smoking Topography Study 2018
Rationale: The World Health Organization Framework Convention on Tobacco Control (WHO FCTC) aims for a regulatory strategy including the regulation of the contents of tobacco products (Article 9).
- Conditions
- Cigarette Smoking, Smoking Behavior, Cigarette Smoking Toxicity
- Trial name
- NCT03498053
- Testing
- Marlboro, Marlboro Prime, Marlboro Prime (ventilation holes taped)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Smoking
Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking
Smoking is the leading cause of preventable death in the United States. An FDA-mandated reduction in the nicotine content of cigarettes might reduce the health burden of tobacco by reducing the prevalence of smoking.
- Trial name
- NCT03311646
- Testing
- Normal nicotine content cigarettes (NNC, Baseline), Very low nicotine content (VLNC)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use
Telehealth-Filter Ventilation ( COMET2P1 )
The goals of this project are to determine the effects of varying degrees of cigarette filter ventilation on biomarkers of toxicant exposure and smoking behavior and on subjective responses to the cigarette.
- Trial name
- NCT04969783
- Testing
- Ventilated Cigarette Filter, Unventilated Cigarette Filter
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Smoking, Tobacco, Smoking Behaviors
Post-Market Surveillance of Tobacco Products
This is a multicenter, post market surveillance study designed to evaluate biomarkers of tobacco exposure and effect, health status measurements, and tobacco product usage patterns in subjects who are natural adopters of…
- Trial name
- NCT04255459
- Testing
- Moist Snuff, Camel Snus, Cigarettes
- Where
- 6 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Cigarette Smoking, Tobacco Use
Gabapentin for Smoking Cessation
Gabapentin is an anti-epileptic agent that has shown preliminary evidence of efficacy for improving symptoms of cocaine and alcohol withdrawal in pilot studies.
- Trial name
- NCT00578552
- Testing
- Gabapentin - 1800 mg/day, Gabapentin - 2700 mg/day
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Electronic Cigarette Use, Pulmonary Disease
Factors That Impact the Relationship Between Pulmonary Status and Susceptibility to Electronic Cigarette Use
The purpose of the study is to explores various psycho-social, physiological, cognitive, behavioral, and environmental factors that may affect the association between pulmonary status and Susceptibility to Electronic Cigarette Use
- Trial name
- NCT04151784
- Testing
- Pulmonary Group, Healthy Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Vascular Reactivity, Serum Biomarkers
MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers
To examine vascular reactivity and inflammatory biomarkers via quantitative magnetic resonance imaging (MRI) and blood serum, respectively, in a crossover study where active vapers (electronic cigarette users) and smokers will…
- Trial name
- AeCE (NCT05271578)
- Testing
- Standardized Electronic Research Cigarette, Nicotine Research Cigarette
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania