Clinical trials: Cigarette Use
Oxidative Stress, Inflammation
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
The goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and…
- Conditions
- Oxidative Stress, Inflammation, Cigarette Smoking
- Trial name
- PSPGL (NCT07316400)
- Testing
- PsP
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Schizophrenia, Nicotine Addiction
Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia
Cigarette smoking rates are extremely high in persons with schizophrenia and this increases the risk of disease and death due to tobacco-related disorders.
- Trial name
- rTMSsmokelab (NCT01523730)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Cigarette Smoking
Effects of Deep Breathing Exercise on Pulmonary Function, Perceived Stress and Physical Fitness Among Healthy Smokers
Effects of deep breathing exercise on pulmonary function, perceived stress and physical fitness among healthy smokers.
- Trial name
- NCT06032793
- Testing
- Breathing exercises
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Smoking
Cue Reactivity in Virtual Reality: The Role of Context
The objectives of this proposal are to examine the role of context in a virtual reality (VR) environment and to explore the extent to which cues (i.e., contextual cues or explicit smoking cues) influence craving and physiological…
- Trial name
- NCT00862927
- Testing
- Breath Sample, Saliva Sample, Questionnaire
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pregnancy
Prenatal Exposure Effects Psychophysiology Study
The purpose of the study is to understand the biology and behavior of early mother-infant attachment, and to investigate how it may be affected by prenatal substance exposures.
- Trial name
- PEEPS (NCT01134770)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Nicotine Dependence
Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use
Oral nicotine pouches (ONPs) are non-combustible nicotine products that may reduce cigarette craving and smoking cue-induced brain activity, supporting their potential as harm-reduction tools for adults who smoke cigarettes.
- Trial name
- NCT07698470
- Testing
- Oral Nicotine Pouch, Smoking Cue Reactivity Task
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
E-Cig Use
Responses to E-Cigarette Advertising
While conventional cigarette use continues to decline among youth and young adults, e-cigarette (EC) use is on the rise. The use of ECs during young adulthood, particularly 18 years of age, is especially alarming because it is…
- Trial name
- NCT04249219
- Testing
- Viewing e-cigarette ads
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Second Hand Tobacco Smoke
Study to Evaluate Constituents in Exhaled Breath and Room Air From Use of E-vapor Products and Conventional Cigarettes
An open-label, single center, three-arm observational study to examine emissions from e-cigarettes versus conventional cigarettes under three environmental settings of typical residential, office and hospitality facilities.
- Trial name
- NCT03605641
- Testing
- JUUL, VUSE Solo, Conventional Cigarette
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Nicotine Dependence, Cigarette Smoking
Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smokers
The goal of this clinical trial is to learn whether lemongrass (Cymbopogon citratus) inhaler and liquid vapor interventions affect nicotine dependence and related biological and behavioral outcomes in adult smokers.
- Conditions
- Nicotine Dependence, Cigarette Smoking, Tobacco Use Disorder, Psychological Stress
- Trial name
- CCIVS (NCT07366294)
- Testing
- Lemongrass Inhaler, Lemongrass Liquid Vapor, Lemongrass Inhaler and Liquid Vapor
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Titin Andri Wihastuti
Smoking ( Cigarette), Cardiovascular Disease
SMOKING AND PRESENCE OF FRANK'S SIGN
In this study, the effect of cigarette smoking-one of the major risk factors for cardiovascular diseases-on the development of Frank's sign (DELC) was investigated.
- Trial name
- NCT07427745
- Testing
- To obtain bilateral ear photographs, To take a medical history
- Where
- Turkey (Türkiye)
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Samsun University
Airway Morbidity, Smoking Cessation
Adverse Airway Effects From Tobacco and E-Cigarettes
The purpose of the study conducted at VA Medical Center in Miami is to determine if smoking electronic cigarettes (known as e-cigarettes) that contain nicotine have less negative effects than regular cigarettes on the person's…
- Conditions
- Airway Morbidity, Smoking Cessation, Nicotine Adverse Reaction, Smoking, Tobacco
- Trial name
- NCT03251053
- Testing
- Electronic cigarette use, Control regular cigarette smokers
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Miami VA Healthcare System
Smoking
E-cigarettes as a Harm Reduction Strategy
E-cigarettes have emerged as an effective strategy for replacing cigarettes among smokers from the general population, but there is a dearth of studies investigating their utility in replacing cigarettes among smokers with opioid…
- Trial name
- NCT06277271
- Testing
- E-cigarette
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Tobacco Use Disorder
Project 2, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Opioid Abusers
This study will examine extended exposure to cigarettes varying in nicotine content among adults with opioid use disorder. Those with opioid use disorder are at increased risk for smoking, nicotine dependence, and using high…
- Trial name
- P2S2 (NCT02250664)
- Testing
- Very low nicotine content cigarettes
- Where
- 2 sites in United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Nicotine Dependence
The Impact of Real-time Functional Magnetic Resonance Imaging (fMRI) Feedback on Response to Nicotine Cues
The purpose of this study is to develop a technique to provide feedback of brain activity and to use this technique to reduce levels of craving in nicotine dependent smokers.
- Trial name
- RTSmoking (NCT01411007)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use
A Study to Evaluate Changes in Smokers Using An Oral Tobacco-Derived Nicotine Product
The purpose of this study was to estimate changes in biomarkers of exposure (BOE) in adult cigarette smokers using an oral tobacco-derived nicotine (OTDN) product relative to adult smokers who continue smoking exclusively.
- Trial name
- NCT04079933
- Testing
- Oral tobacco-derived nicotine product (OTDN)
- Where
- 3 sites in United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Altria Client Services LLC
Smoking Prevention and Control
Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes
In a 2x2 design, current menthol smokers (N=240) will complete a baseline period before being assigned to a cigarette (menthol or non-menthol) and e-cigarette condition (menthol or tobacco-flavored e-liquid) and receiving a…
- Trial name
- NCT05896033
- Testing
- Non-Menthol Cigarettes, Tobacco Flavored E-cigarettes, Menthol Cigarettes
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking
Impact of Graphic Cigarette Warnings
The purpose of this randomized controlled trial is to determine whether graphic health warnings on cigarette packs are more effective than the existing Surgeon General's warning on cigarette packs at encouraging quit attempts.
- Trial name
- NCT02247908
- Testing
- Surgeon General's Warning, Graphic Warning
- Where
- 2 sites in United States
- Volunteers
- 2,149 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cigarette Smoking, Tobacco Use
Gabapentin for Smoking Cessation
Gabapentin is an anti-epileptic agent that has shown preliminary evidence of efficacy for improving symptoms of cocaine and alcohol withdrawal in pilot studies.
- Trial name
- NCT00578552
- Testing
- Gabapentin - 1800 mg/day, Gabapentin - 2700 mg/day
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cigarette Smoking
Tailored Web and Peer Email Cessation Counseling for College Smokers
The RealU2 is a randomized controlled trial to determine the efficacy of an online health and wellness program for young adults with the addition of individualized peer health coaching.
- Trial name
- RealU (NCT01604525)
- Testing
- Tailored Web, Peer Coaching, Untailored Web
- Volunteers
- 1,699 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Smoking
Internet Stop Smoking Study - Phase VI
The purpose of this study is to determine the percentage of English- and Spanish-speaking smokers worldwide who can stop smoking using an Internet stop smoking site. Latinos and non-Latinos are welcome to participate.
- Trial name
- TC4 (NCT00721786)
- Testing
- UCSF/SFGH Internet Stop Smoking Study site
- Where
- United States
- Volunteers
- 18,154 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco