Clinical trials: Cigarette Use
Nicotine Use Disorder, Tobacco Use Disorder
Evaluation of the Addictive Potential of E-Cigarettes
This study will examine the subject matter from a neurobiological and a neuropsychological vantage point to ascertain whether the e-cigarette is potentially as addictive as the traditional tobacco cigarette.
- Trial name
- EVAPE (NCT04772014)
- Where
- Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Smoking, Tobacco
The Cardiovascular Impacts of Electronic Cigarettes in Comparison to the Use of Nicotine Replacement Patches
In Scotland tobacco-related illnesses account for in excess of 56,000 hospital admissions and a quarter of deaths each year. The resultant financial impact on NHS Scotland is over £300 million per annum.
- Trial name
- VAPOUR (NCT03358953)
- Testing
- Electron Cigarette, Nicotine Replacement Patch
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases
The Efficacy and Safety of Electronic Cigarettes: a 5-year Follow-up Study
The main aim of this multicentric 5-year follow-up study is to evaluate for the first time the long-term efficacy and safety (in terms of smoking-related serious diseases requiring hospitalization) of e-cigarette smoking…
- Conditions
- Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases, Cancer of the Lung, Cancer of the Bladder
- Trial name
- NCT01785537
- Where
- Italy
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Tobacco Use
Expanding the Click City Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products
The goal of this study is to modify a smoking prevention program for 5th and 6th grade students to also target vaping e-cigarettes.
- Trial name
- NCT03682900
- Testing
- Click City®: Tobacco, Usual Tobacco Curriculum
- Where
- United States
- Volunteers
- 2,673 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Smoking Cessation, Electronic Cigarette Use
Comparison of Nicotine Replacement Therapy and Electronic Cigarettes for Smoking Cessation in Pakistan
Smoking is prevalent in Pakistan, and a large proportion of the adult population smokes cigarettes or uses other forms of tobacco.
- Trial name
- NCT06063421
- Testing
- Electronic Cigarette (EC), Nicotine Replacement Therapy
- Where
- Pakistan
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Strategic Health Research Limited
Smoking Cessation, Cigarette Smoking
Treating Smokers With Mental Illness
This is a smoking cessation study that will enroll smokers who have been diagnosed with a severe mental illness. The study will use a combination of intensive tobacco treatment counseling and nicotine replacement therapy to…
- Conditions
- Smoking Cessation, Cigarette Smoking, Schizophrenia, Psychotic Disorders
- Trial name
- NCT03822416
- Testing
- Nicotine patch, Nicotine lozenge, Therapy
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Smoking, Nicotine Dependence
Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace
This project will examine the impact of very low nicotine content (VLNC) cigarettes in a complex tobacco and nicotine product marketplace.
- Trial name
- NCT03272685
- Testing
- Very Low Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
- Where
- 6 sites in United States
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
E-Cig Use
Psychometric Properties of the Chinese Version of Penn State [Electronic] Cigarette Dependence Index
The purpose of this study is to realize the first evaluation of the psychometric characteristics of the Chinese version of the the Penn State University Electronic Cigarette Dependence Index Scale.
- Trial name
- NCT05477888
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cigarette Smoking, Smoking Cessation
Benefits of Tobacco Free Cigarette
Background. Smoking is considered a global public health problem. For this reason, the smoking dependence was called by experts as a global epidemic.
- Trial name
- BETOFREE (NCT02422914)
- Testing
- Smoking cessation program TFC and activity tracker, Smoking cessation program TFC-free and activity tracker, Smoking cessation program and activity tracker
- Where
- Italy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Milan
Electronic Cigarette Use
Effects of Nicotine Salt Aerosol on Cigarette Smokers
This grant compares the effects of cigarette smoking, protonated nicotine ("salt") aerosol through an Electronic Nicotine Delivery System (ENDS), and unprotonated nicotine aerosol through an ENDS on nicotine delivery, nicotine…
- Trial name
- NCT03974152
- Testing
- Subox Mini C with Avail 18 mg nicotine salt (protonated), Subox Mini C with Avail 18 mg nicotine (unprotonated), Own brand cigarette
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Smoking, Cigarette
Dyadic Financial Incentive Treatments for Dual Smoker Couples
Smokers partnered with other smokers (i.e., dual-smoker couples) represent ~2/3 of all smokers. Dual-smoker couples (DSCs) are less likely to try to quit smoking and more likely to relapse during a quit attempt, reducing overall…
- Trial name
- NCT06296849
- Testing
- Financial Incentive Treatment (FIT)
- Where
- 2 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cigarette Smoking, Tobacco Smoking
Working Inside for Smoking Elimination
The purpose of this study is to determine the extent to which an Intentional Behavioral Intervention will increase tobacco quit rates post release among incarcerated men and women.
- Trial name
- WISE (NCT01122589)
- Testing
- Motivational Interviewing/CBT, CONcise Tapes Reviewing Obstacles to healthy Living (CONTROL)
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Nicotine Dependence, Cigarettes
Epidemiology and Acute Oral Effects Electronic Cigarette
Electronic cigarettes are battery-powered vaporizers which have a similar feel to tobacco smoking. They do not produce cigarette smoke but rather an aerosol, which is frequently referred to as vapor.
- Trial name
- NCT03011710
- Testing
- ProVari v2.5 (E-cigarette), Marlboro Gold (Conventional cigarette), Cigarette tip
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
E-Cig Use
The Impact of Policies Regarding E-cigarette on Adolescents and Young Adults' Cognition and Behavior for E-cigarette
Based on the Knowledge，Attitude，Belief and Practice model(KABP model), this study intends to use a mixed method to explore the influencing mechanism of youth and adolescents' cognition and behavior for e-cigarette before and…
- Trial name
- NCT05482581
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Alcohol Use, E-cigarette Use
Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use
A high priority research area for the Food and Drug Administration Center for Tobacco Products (FDA CTP) is determining who will start using tobacco products and who will stop using tobacco products.
- Conditions
- Alcohol Use, E-cigarette Use, Cigarette Use
- Trial name
- NCT07010601
- Testing
- Experimental Tobacco Marketplace, Hypothetical Novel Nicotine Product Purchase Tasks
- Where
- United States
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- Mark J Rzeszutek, PhD
Smoking
Monitoring the Transition From Smoking to E-cigarettes
Electronic cigarettes (e-cigarettes) have proved very popular and a meteoric rise in their usage is currently under way. People purchase them as an aid to giving up smoking, to reduce cigarette consumption, to minimise withdrawal…
- Trial name
- NCT02752022
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Smoking, Tobacco Smoking
CSD1601: A Study to Evaluate the Exposure to Tar and Nicotine From Two Cigarette Products That Contain a Menthol Capsule in the Filter
This study will evaluate exposure to tar and nicotine from two cigarette products that contain a menthol capsule in the filter, and provide a basis for comparing mouth-level exposure when smokers smoke the two cigarette products.
- Conditions
- Smoking, Tobacco Smoking, Tobacco Use
- Trial name
- NCT04529551
- Testing
- 1601A, 1601B
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Tobacco Use Disorder
Switching to Very Low Nicotine Content Cigarettes vs Reducing Cigarettes Per Day
The FDA recently gained the authority to regulate the nicotine content of cigarettes. Prior research suggests that smokers who switch to very low nicotine content (VLNC) cigarettes experience reduced addiction to nicotine and are…
- Trial name
- NCT03060083
- Testing
- Very low nicotine content (VLNC) cigarettes and nicotine replacement therapy (NRT), Reduce cigarettes per day (CPD) with nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Cigarette Smoking
Effects of Smoking Environments on Brain Reactivity
The goal of this study is to evaluate correlations between brain reactivity (as assessed via functional magnetic resonance imaging (fMRI) following 24-h abstinence) and the amount of smoking in a specific location.
- Trial name
- CameraCue3 (NCT03421210)
- Testing
- Nicotine patch
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Duke University
Tobacco Dependence
Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status
The overall goal of this study is to address the question of whether progressively lowering nicotine content in cigarettes can reduce or eliminate nicotine dependence in smokers of low socioeconomic status
- Trial name
- NCT01928719
- Testing
- Reduced Nicotine Content Cigarettes, Same Nicotine Content Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center