Clinical trials: Cigarette Use
Tobacco Dependence
Low Nicotine Cigarettes Plus Electronic Cigarettes
This study aims to determine the health effects of very low nicotine content in cigarettes, in conjunction with the availability of nicotine-containing electronic cigarettes (e-cigs) among smokers with mental health conditions…
- Trial name
- NCT04058717
- Testing
- Normal Nicotine Content research cigarettes, High Nicotine e-cigarette, Very Low Nicotine Content research cigarettes
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Nicotine Dependence, Cigarettes
Epidemiology and Acute Oral Effects Electronic Cigarette
Electronic cigarettes are battery-powered vaporizers which have a similar feel to tobacco smoking. They do not produce cigarette smoke but rather an aerosol, which is frequently referred to as vapor.
- Trial name
- NCT03011710
- Testing
- ProVari v2.5 (E-cigarette), Marlboro Gold (Conventional cigarette), Cigarette tip
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Tobacco Use Disorder
Menthol Flavored E-cigarette Use During a Simulated Ban of Menthol Cigarettes
The purpose of this formative study is to provide preliminary data regarding how the availability of menthol flavored e-cigarettes affects tobacco use behavior in the context of a ban on menthol flavored cigarettes
- Trial name
- NCT03164668
- Testing
- menthol flavored e-cigarette, tobacco flavored e-cigarette
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking
Nicotine Pharmacokinetic Profile of the CHTP 1.1 M
The primary objective of this clinical study is to evaluate the pharmacokinetic (PK) profile of nicotine (rate and amount of nicotine absorbed) after single use of the Carbon Heated Tobacco Product 1.1 Menthol (CHTP 1.1 M), a…
- Trial name
- NCT02466412
- Testing
- CHTP 1.1 M, mCC
- Where
- Japan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Obesity, Overweight
Semaglutide for Post-Smoking Cessation Weight Management
This trial will examine the effect of semaglutide 2.4mg on changes in body weight, body composition, and peripheral and central mechanisms that control appetite, satiety, and food intake in the context of smoking cessation.
- Conditions
- Obesity, Overweight, Cigarette Smoking
- Trial name
- NCT06173778
- Testing
- semaglutide 2.4mg, Nicotine Replacement Therapy (NRT, nicotine patch), Brief Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cigarette Smoking, Tobacco Use Disorder
Intervention Trial of Culturally-Appropriate Decision Aids for Smoking Cessation
Despite the establishment of various smoking cessation methods, including pharmacological intervention, only a small proportion of smokers who visit doctors choose to receive such assistance.
- Conditions
- Cigarette Smoking, Tobacco Use Disorder, Nicotine Dependence, Smoking Cessation
- Trial name
- NCT01566097
- Testing
- Smoking Cessation Decision Aids
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Electronic Cigarette Use, Retina; Change
Nicotine Influence on the Retina Following the Use of Electronic Cigarette
The marketing of electronic cigarettes (e-cigarettes) in 2003 was initially intended to present a healthier alternative to smokers.
- Trial name
- NCT05801419
- Testing
- RETI-port/scan 21, Zilia Ocular, OCT-A
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Christian Casanova
Tobacco Use, Cigarette Smoking
Assessing Tobacco Product Choice When the Cost of Menthol Cigarettes Increases
In this study, participants will complete a behavioral economics laboratory task and validation field assessments to understand how menthol cigarette policy restrictions may affect tobacco product purchasing and use.
- Trial name
- NCT03612349
- Testing
- Experimental Tobacco Marketplace Task
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University
E-cigarette Use
An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults
The goal of this intervention development and pilot clinical trial is to determine whether receiving the brief online intervention results in greater reductions in past 7-day e-cigarette use frequency and smoking susceptibility…
- Trial name
- NCT06129123
- Testing
- Live Free From E-cigarettes
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Nicotine Dependence
Multiple Cigarette Induced Changes in Hormone Function, Mood States and Behavior
The proposed clinical studies will analyze the interactions between nicotine, alterations in endocrine hormones, mood and cardiovascular measures. They also intend to examine the contribution of gender and menstrual cycle phase.
- Trial name
- NCT01636310
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Nicotine Administration & Dosage, E-cigarettes
Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes
This is an observational, crossover design that will examine the pharmacokinetics and pharmacodynamics of impact of smoking tobacco cigarettes or vaping the JUUL electronic cigarette.
- Conditions
- Nicotine Administration & Dosage, E-cigarettes, Vaping, E-Liquid
- Trial name
- NCT04053868
- Testing
- JUUL, Tobacco
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation, Smoking
Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention
The objective of this R01 application is to conduct a randomized controlled trial to test the efficacy of the Be Smoke Free, telephone-based, guided imagery (GI) intervention (IC) for smoking cessation compared to active…
- Conditions
- Smoking Cessation, Smoking, Smoking Reduction, Smoking, Cigarette
- Trial name
- NCT05277831
- Testing
- Guided Imagery Intervention, Standard Behavioral Control
- Where
- United States
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Smoking Behaviors, Periodontal Health
Effects of E-Cigarette Use on Oxidative Stress and Matrix Degradation
This cross-sectional observational study aims to investigate the effects of e-cigarette use on oxidative and matrix-degrading pathways in periodontally healthy individuals.
- Trial name
- ECIG-FOXO (NCT07338318)
- Testing
- E-Cigarette Use
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Electronic Cigarette Use
Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)
This study aims to better understand how e-cigarettes (ECIG) nicotine flux impacts several behavioral economic measures of abuse liability.
- Trial name
- NCT04332926
- Testing
- Tobacco product administration and assessment, own brand cigarettes, Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Passive Exposure to Electronic Cigarette Aerosols
Exposure to E-cigarette Aerosols in Real-life Conditions
Objective: To investigate in real-life conditions passive exposure to aerosols from the use of e-cigarettes among people who cohabit with e-cigarette users.
- Trial name
- NCT04140630
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Cigarette Smoking, Nicotine Dependence
Smokers' Response to Nicotine Dependence Genotyping
Innovative strategies to reduce adult smoking prevalence include using genetic information to motivate cessation and, ultimately, to tailor cessation pharmacotherapy.
- Trial name
- NCT01780038
- Testing
- Receipt of Genetic Results, No results given
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Smoking Cessation, Cigarette Smoking
Treating Smokers With Mental Illness
This is a smoking cessation study that will enroll smokers who have been diagnosed with a severe mental illness. The study will use a combination of intensive tobacco treatment counseling and nicotine replacement therapy to…
- Conditions
- Smoking Cessation, Cigarette Smoking, Schizophrenia, Psychotic Disorders
- Trial name
- NCT03822416
- Testing
- Nicotine patch, Nicotine lozenge, Therapy
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiovascular Risk Factor, Nicotine Dependence
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power
This study will examine the short-term cardiovascular (CV) effects of e-cigarette device power in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21).
- Trial name
- TCORS-1 (NCT03839745)
- Testing
- Electronic Cigarette
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cigarette Smoking
Comparison of Low Yield Cigarettes in African Americans vs. Whites
The investigators' general hypothesis is that African-Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater…
- Trial name
- 6162-AAPK2 (NCT01058876)
- Testing
- Deuterated nicotine and cotinine
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cigarette Smoking, Tobacco Smoking
Working Inside for Smoking Elimination
The purpose of this study is to determine the extent to which an Intentional Behavioral Intervention will increase tobacco quit rates post release among incarcerated men and women.
- Trial name
- WISE (NCT01122589)
- Testing
- Motivational Interviewing/CBT, CONcise Tapes Reviewing Obstacles to healthy Living (CONTROL)
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island